Results 41 to 50 of about 367,353 (219)

Clear Cell Renal Cell Carcinoma: From Biology to Treatment

Cancers, 2023
Simple Summary Over the past two decades, biological discoveries have transformed the treatment strategies for renal cell carcinoma. These advances have led to the development of agents targeting pro-angiogenic pathways and the immunogenicity of renal ...
A. Kase, D. George, Sundhar Ramalingam
semanticscholar   +1 more source

Prognostic relevance of the histological subtype of renal cell carcinoma [PDF]

, 2008
OBJECTIVE: According to several studies, when the histological subtype of renal cell carcinoma is established it is possible to attribute a different life expectancy to each patient.
ANTUNES, Alberto A., DALL'OGLIO, Marcos F., LEITE, Katia R. M., MOSCONI, Alcides, POMPEO, Antonio C., Srougi, Miguel   +5 more
core   +2 more sources

Intratumoral CXCL13+CD8+T cell infiltration determines poor clinical outcomes and immunoevasive contexture in patients with clear cell renal cell carcinoma

Journal for ImmunoTherapy of Cancer, 2021
Background Chemokine (C-X-C motif) ligand 13 (CXCL13) was known as a selective chemotaxis for B cells, a product of follicular helper CD4+T cells (TFH) and a contributor to tertiary lymphoid structures (TLS).
S. Dai, Han Zeng, Zhao-xia Liu, Kaifeng Jin, Wenbin Jiang, Zewei Wang, Zhi-Yuan Lin, Y. Xiong, Jiajun Wang, Yuan Chang, Q. Bai, Yu Xia, Li Liu, Yu Zhu, Le Xu, Yang Qu, Jianming Guo, Jiejie Xu   +17 more
semanticscholar   +1 more source

Chromosome 9p deletion in clear cell renal cell carcinoma predicts recurrence and survival following surgery [PDF]

, 2014
BACKGROUND: Wider clinical applications of 9p status in clear cell renal cell carcinoma (ccRCC) are limited owing to the lack of validation and consensus for interphase fluorescent in situ hybridisation (I-FISH) scoring technique.
Bondad, J., Cunningham, J., El-Mokadem, I., Fitzpatrick, J., Fleming, S., Nabi, G., Pratt, N., Rauchhaus, P.   +7 more
core   +4 more sources

Clear Cell Adenocarcinoma of the Ureter Similar to Clear Cell Renal Cell Carcinoma Histology

Case Reports in Urology, 2021
A 70-year-old woman was referred to our hospital with gross hematuria and diagnosed with right invasive ureteral cancer and bladder urothelial carcinoma in situ.
Kazuhiro Watanabe, Go Hasegawa, Yohei Ikeda, Noboru Hara, Tsutomu Nishiyama   +4 more
doaj   +1 more source

A deep learning framework for automated classification of histopathological kidney whole-slide images

Journal of Pathology Informatics, 2022
Background: Renal cell carcinoma is the most common type of malignant kidney tumor and is responsible for 14,830 deaths per year in the United States. Among the four most common subtypes of renal cell carcinoma, clear cell renal cell carcinoma has the ...
Hisham A. Abdeltawab, Fahmi A. Khalifa, Mohammed A. Ghazal, Liang Cheng, Ayman S. El-Baz, Dibson D. Gondim   +5 more
doaj   +1 more source

Treatment strategies for clear cell renal cell carcinoma: Past, present and future

Frontiers in Oncology, 2023
Clear cell renal cell carcinoma (ccRCC) is the most prevalent histological subtype of kidney cancer, which is prone to metastasis, recurrence, and resistance to radiotherapy and chemotherapy.
Junwei Yang, Kuansong Wang, Zhichun Yang
semanticscholar   +1 more source

An Immune Atlas of Clear Cell Renal Cell Carcinoma

Cell, 2017
Summary Immune cells in the tumor microenvironment modulate cancer progression and are attractive therapeutic targets. Macrophages and T cells are key components of the microenvironment, yet their phenotypes and relationships in this ecosystem and to ...
Stéphane Chevrier, Jacob H. Levine, V. R. Zanotelli, K. Silina, D. Schulz, M. Bacac, Carola H. Ries, L. Ailles, M. Jewett, H. Moch, M. van den Broek, C. Beisel, Michael B. Stadler, C. Gedye, Bernhard Reis, D. Pe’er, B. Bodenmiller   +16 more
semanticscholar   +1 more source

The Tumor Immune Microenvironment in Clear Cell Renal Cell Carcinoma

International Journal of Molecular Sciences, 2023
Clear cell renal cell carcinoma (ccRCC) is a type of kidney cancer that arises from the cells lining the tubes of the kidney. The tumor immune microenvironment (TIME) of ccRCC is a complex interplay of various immune cells, cytokines, and signaling ...
Cesar U. Monjaras-Avila, A. C. Lorenzo-Leal, A. C. Luque-Badillo, N. D'Costa, C. Chavez-Muñoz, H. Bach   +5 more
semanticscholar   +1 more source

Clear Cell Papillary Renal Cell Carcinoma in the Bilateral Native Kidneys after 2 Years of Renal Transplantation: Report of a Case and Review of the Literature

Case Reports in Transplantation, 2011
Renal transplantation increases the probability of malignant tumors by about 2–4-fold overall with a much higher rate for renal epithelial malignancy.
Zhanyong Bing, John E. Tomaszewski
doaj   +1 more source