Results 21 to 30 of about 8,019,599 (294)

Renal Lipid Metabolism Abnormalities in Obesity and Clear Cell Renal Cell Carcinoma

Metabolites, 2021
Clear cell renal cell carcinoma is the most common and deadly type of cancer affecting the kidney, and is characterized histologically by large intracellular lipid deposits.
Ion Alexandru Bobulescu, Laurentiu M. Pop, Chinnadurai Mani, Kala Turner, Christian Rivera, Sabiha Khatoon, Subash Kairamkonda, Raquibul Hannan, Komaraiah Palle   +8 more
doaj   +1 more source

Renal Cell Carcinoma With Clear Cell and Papillary Features [PDF]

Archives of Pathology & Laboratory Medicine, 2012
Context.—The diagnosis of primary renal cell carcinomas (RCCs) with both papillary architecture and cells with clear cytoplasm can be diagnostically challenging for practicing pathologists. The 4 main neoplasms in the differential diagnosis are clear cell RCC, papillary RCC, clear cell papillary RCC, and Xp11 translocation RCC.
ROSS H., MARTIGNONI, Guido, ARGANI P.
openaire   +2 more sources

Timing the Landmark Events in the Evolution of Clear Cell Renal Cell Cancer: TRACERx Renal.

, 2022
Clear cell renal cell carcinoma (ccRCC) is characterized by near-universal loss of the short arm of chromosome 3, deleting several tumor suppressor genes. We analyzed whole genomes from 95 biopsies across 33 patients with clear cell renal cell carcinoma.
Raine, K, Yates, LR, Teague, J, Lopez, JI, Gore, M, Rowan, A, Mitchell, TJ, Lynch, AG, Au, L, Stewart, A, Litchfield, K, Turajlic, S, Tarpey, P, Chandra, A, Csabai, I, Swanton, C, Fotiadis, N, Lynch, J, Soultati, A, Challacombe, B, Xu, H, Hazell, S, Stamp, G, Elaidi, R, Horswell, S, Campbell, PJ, Chowdhury, S, Butler, AP, Rudman, S, Wedge, DC, Futreal, PA, Nicol, D, Farmery, JHR, O'Brien, T, Maura, F, McGranahan, N, TRACERx Renal Consortium,, Spain, L, Stewart, GD, Szallasi, Z, Martincorena, I, Stares, M, Fernando, A, Larkin, J, Oudard, S, Pickering, L, Chambers, T, Angelopoulos, N   +47 more
core   +1 more source

Chromosome 9p deletion in clear cell renal cell carcinoma predicts recurrence and survival following surgery [PDF]

, 2014
Background:Wider clinical applications of 9p status in clear cell renal cell carcinoma (ccRCC) are limited owing to the lack of validation and consensus for interphase fluorescent in situ hybridisation (I-FISH) scoring technique.
Fleming, S., P Rauchhaus, J Fitzpatrick, Fitzpatrick, J., N Pratt, S Fleming, J Bondad, J Cunningham, El-Mokadem, I., Cunningham, J., Bondad, J., Nabi, G., Rauchhaus, P., G Nabi, Pratt, N., I El-Mokadem   +15 more
core   +1 more source

Differential expression of prognostic proteomic markers in primary tumour, venous tumour thrombus and metastatic renal cell cancer tissue and correlation with patient outcome [PDF]

, 2013
Renal cell carcinoma (RCC) is the most deadly of urological malignancies. Metastatic disease affects one third of patients at diagnosis with a further third developing metastatic disease after extirpative surgery.
Antony C P Riddick, Stewart Grant D., Laird Alexander, Alexander Laird, Grant D Stewart, Laird, Alexander, O'Mahony, Fiach C, Riddick, Antony C P, Riddick Antony C. P., O’Mahony Fiach C., Harrison David J., Fiach C O'Mahony, Jyoti Nanda, Harrison, David J, David J Harrison, O'Mahony, Fiach C., Riddick, Antony C. P., Nanda Jyoti, Nanda, Jyoti, Stewart, Grant D., O’Donnell Marie, O'Donnell, Marie, Stewart, Grant D, Marie O'Donnell, Harrison, David J., Harrison, David J.; id_orcid   +25 more
core   +2 more sources

The use of automated quantitative analysis to evaluate epithelial-to-mesenchymal transition associated proteins in clear cell renal cell carcinoma [PDF]

, 2012
Background: Epithelial-to-mesenchymal transition (EMT) has recently been implicated in the initiation and progression of renal cell carcinoma (RCC). Some mRNA gene expression studies have suggested a link between the EMT phenotype and poorer clinical ...
Antony C P Riddick, Stewart Grant D., Faratian Dana, Theodoulou Marianna, Grant D Stewart, Dana Faratian (171110), O'Mahony Fiach C., O'Mahony, Fiach C, James Varley (181899), David J. Harrison (171106), Jyoti Nanda (181902), Riddick, Antony C P, Varley James, Marianna Theodoulou, Dana Faratian, Varley, James, Riddick Antony C. P., Harrison David J., Fiach C O'Mahony, Antony C. P. Riddick (145315), Jyoti Nanda, Harrison, David J, David J Harrison, O'Mahony, Fiach C., Faratian, Dana, Riddick, Antony C. P., Nanda Jyoti, Marianna Theodoulou (181905), Grant D. Stewart (145312), Theodoulou, Marianna, Nanda, Jyoti, Stewart, Grant D., James Varley, Stewart, Grant D, Fiach C. O'Mahony (181892), Harrison, David J., Harrison, David J.; id_orcid   +36 more
core   +3 more sources

Ipsilateral synchronous clear and papillary renal cell carcinoma: A case report and review of the literature

Urology Case Reports, 2018
Clear cell renal cell carcinoma and papillary renal cell carcinoma are the most common types of renal tumors. However, coexistence of both tumors in the same kidney is a rare condition.We report a 56-year old male who was found to have ipsilateral ...
Muna Alhusban, Sohaib Alhamss, Bayan Alzumaili, Ali Al-Daghmin   +3 more
doaj   +1 more source

Cellular milieu in clear cell renal cell carcinoma

Frontiers in Oncology, 2022
Clear cell renal cell carcinoma (ccRCC) is globally the most prevalent renal cancer. The cells of origin in ccRCC have been identified as proximal tubular epithelial cells (PTEC); however, the transcriptomic pathways resulting in the transition from ...
Arti M. Raghubar, Arti M. Raghubar, Arti M. Raghubar, Arti M. Raghubar, Arti M. Raghubar, Matthew J. Roberts, Matthew J. Roberts, Matthew J. Roberts, Matthew J. Roberts, Simon Wood, Simon Wood, Helen G. Healy, Helen G. Healy, Helen G. Healy, Andrew J. Kassianos, Andrew J. Kassianos, Andrew J. Kassianos, Andrew J. Mallett, Andrew J. Mallett, Andrew J. Mallett, Andrew J. Mallett   +20 more
doaj   +1 more source

Role of tumor-derived exosomes in metastasis, drug resistance and diagnosis of clear cell renal cell carcinoma

Frontiers in Oncology, 2022
Renal cancer is one of the most extensively studied human tumors today, with clear cell renal cell carcinoma accounting for approximately 80% of all cases.
Tiancheng Jiang, Tiancheng Jiang, Zepeng Zhu, Zepeng Zhu, Jiawei Zhang, Jiawei Zhang, Ming Chen, Ming Chen, Shuqiu Chen, Shuqiu Chen   +9 more
doaj   +1 more source

Significance of chromosome 9p status in renal cell carcinoma:a systematic review and quality of the reported studies [PDF]

, 2014
Defining the prognosis of renal cell carcinoma (RCC) using genetic tests is an evolving area. The prognostic significance of 9p status in RCC, although described in the literature, remains underutilised in clinical practice. The study explored the causes
El-Mokadem, Ismail, Fitzpatrick, John, Cunningham, J., Nabi, Ghulam, Pratt, Norman, Fleming, Stewart, Rai, Bhavan   +6 more
core   +1 more source