Results 41 to 50 of about 8,019,599 (294)

Clinical, molecular, and genetic correlates of lymphatic spread in clear cell renal cell carcinoma [PDF]

, 2012
While it is well known that clear cell renal cell carcinoma (ccRCC) that presents with lymphatic spread is associated with an extremely poor prognosis, its molecular and genetic biology is poorly ...
Zomorodian, Nazy, Seligson, David B, Rampersaud, Edward N, Klatte, Tobias, Kroeger, Nils, Birkhäuser, Frédéric D, Belldegrun, Arie S, Leppert, John T, Kabbinavar, Fairooz F, Pantuck, Allan J, Rao, P Nagesh   +10 more
core   +1 more source

Metastatic renal cell carcinoma initially presenting with hematochezia and subsequently with vaginal bleeding: a case report

BMC Urology, 2018
Background We report an unusual case of a synchronous rectal and metachronous vaginal metastatic renal cell carcinoma. Case presentation A 78-year-old woman presented with hematochezia and a colonoscopy revealed a metastatic clear-cell renal cell ...
Simon Ouellet, Audrey Binette, Alexander Nguyen, Perrine Garde-Granger, Robert Sabbagh   +4 more
doaj   +1 more source

Clear Cell Papillary Renal Cell Carcinoma in the Bilateral Native Kidneys after 2 Years of Renal Transplantation: Report of a Case and Review of the Literature

Case Reports in Transplantation, 2011
Renal transplantation increases the probability of malignant tumors by about 2–4-fold overall with a much higher rate for renal epithelial malignancy.
Zhanyong Bing, John E. Tomaszewski
doaj   +1 more source

A deep learning framework for automated classification of histopathological kidney whole-slide images

Journal of Pathology Informatics, 2022
Background: Renal cell carcinoma is the most common type of malignant kidney tumor and is responsible for 14,830 deaths per year in the United States. Among the four most common subtypes of renal cell carcinoma, clear cell renal cell carcinoma has the ...
Hisham A. Abdeltawab, Fahmi A. Khalifa, Mohammed A. Ghazal, Liang Cheng, Ayman S. El-Baz, Dibson D. Gondim   +5 more
doaj   +1 more source

Immunotherapy of Clear-Cell Renal-Cell Carcinoma

Cancers
Clear-cell Renal-Cell Carcinoma (ccRCC) is the most common type of renal-cell carcinoma (RCC). In many cases, RCC patients manifest the first symptoms during the advanced stage of the disease. For this reason, immunotherapy appears to be one of the dominant treatments to achieve a resolution.
Sophie Grigolo, Luis Filgueira
openaire   +2 more sources

Cell surface engineering of renal cell carcinoma with glycosylphosphatidylinositol-anchored TIMP-1 blocks TGF-beta 1 activation and reduces regulatory ID gene expression [PDF]

, 2012
Tissue inhibitor of metalloproteinase 1 (TIMP-1) controls matrix metalloproteinase activity through 1:1 stoichiometric binding. Human TIMP-1 fused to a glycosylphosphatidylinositol (GPI) anchor (TIMP-1-GPI) shifts the activity of TIMP-1 from the ...
Notohamiprodjo, Susan, Jaeckel, Carsten, Djafarzadeh, Roghieh, Hofstetter, Monika, Nelson, Peter J., Rieth, Nicole   +5 more
core   +1 more source

Temsirolimus for patients with metastatic renal cell carcinoma : outcomes in patients receiving temsirolimus within a compassionate use program in a tertiary referral center [PDF]

, 2014
Aim: Temsirolimus has shown efficacy as first-line treatment of patients with metastatic renal cell carcinoma and poor prognostic features. The efficacy of temsirolimus in other clinical settings, such as second-line therapy, is unclear.
Pascoe, Jennifer, Afshar, Mehran, Porfiri, Emilio, Whitmarsh, Sue, James, Nicholas D.   +4 more
core   +1 more source

Clear Cell Papillary Renal Cell Carcinoma: A Potential Mimic of Conventional Clear Cell Renal Carcinoma on Core Biopsy

Case Reports in Urology, 2015
Clear cell papillary renal cell carcinoma (CCP-RCC) is a recently described, relatively uncommon variant of renal cell carcinoma (RCC) with a reported incidence of 4.1%. Thought to only arise in those with end stage renal disease, CCP-RCC is increasingly
Heath Liddell, Anton Mare, Sean Heywood, Genevieve Bennett, Hin Fan Chan   +4 more
doaj   +1 more source

Downregulation of CIP2A inhibits cancer cell proliferation and vascularization in renal clear cell carcinoma

Biomedical Papers, 2020
Background: CIP2A has been proved to play a role as an oncogene in various types of malignancies while its functionality in renal clear cell carcinoma has not been investigated.
Hui Gao, Yuqiao Li, Tao Lin, Yan Cheng, Yunbo Ma   +4 more
doaj   +1 more source

MiR-935 Promotes Clear Cell Renal Cell Carcinoma Migration and Invasion by Targeting IREB2 [Retraction]

Cancer Management and Research, 2020
Liu F, Chen Y, Chen B, Liu C, Xing J. Cancer Manag Res. 2019;11:10891–10900. At the authors request, the Editor-in-Chief and Publisher of Cancer Management and Research wish to retract the published article.
Liu F, Chen Y, Chen B, Liu C, Xing J
doaj