Results 31 to 40 of about 8,019,599 (294)

The long noncoding RNA urothelial carcinoma-associated 1 overexpression as a poor prognostic biomarker in clear cell renal cell carcinoma

Tumor Biology, 2017
Long noncoding RNA urothelial carcinoma-associated 1 has previously played important roles in cancer. However, its role is still unknown in clear cell renal cell carcinoma.
Yang Wang, Wen Gao, Jiali Xu, Yizhi Zhu, Lingxiang Liu   +4 more
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Metabolic reprogramming of clear cell renal cell carcinoma

Frontiers in Endocrinology, 2023
Clear cell renal cell carcinoma (ccRCC) is a malignancy that exhibits metabolic reprogramming as a result of genetic mutations. This reprogramming accommodates the energy and anabolic needs of the cancer cells, leading to changes in glucose, lipid, and ...
Haiyan Zhu, Xin Wang, Shihao Lu, Kongbo Ou   +3 more
doaj   +1 more source

Antigenic targets in clear cell renal cell carcinoma

Kidney Cancer, 2023
Immune checkpoint inhibitors (ICIs) have transformed the management of advanced renal cell carcinoma (RCC), but most patients still do not receive a long-term benefit from these therapies, and many experience off-target, immune-related adverse effects ...
Nicholas R. Schindler, David A. Braun
doaj   +1 more source

Heart Metastases of Clear Cell Renal Cell Carcinoma

Diagnostics, 2023
Renal cell carcinoma (RCC) is a common genitourinary cancer. Of the several histologic types of RCC, clear cell renal cell carcinoma (ccRCC) is the most frequent.
Katarzyna Romejko, Adam Rytel, Tomasz Rozmyslowicz, Stanisław Niemczyk   +3 more
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Synchronous bilateral renal cell carcinomas with differing histologies

IJU Case Reports, 2020
Introduction Bilateral renal cell carcinomas with different histological types are rare. We report herein the first description of bilateral renal carcinomas with clear cell renal cell carcinoma and mucinous tubular and spindle cell carcinoma occurring ...
Ryu Shigehisa, Takashi Karashima, Shu Kobayashi, Kaya Atagi, Daigo Takemori, Hideo Fukuhara, Satoshi Fukata, Ichiro Murakami, Naoto Kuroda, Keiji Inoue   +9 more
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Risk Factors and Histopathological Features of Renal Cell Carcinoma Subtypes [PDF]

Translational Research in Urology, 2022
Introduction: Kidney cancer is currently the 9th most common cancer in men and the 14th most common in women. Renal cell carcinoma (RCC) is the most common type of kidney cancer, accounting for about 85% of all renal malignancies. It accounts for about 2%
Anahita Ansari Djafari, Babakak Javanmard, Seyyed Ali Hojjati, Saba Faraji, Maryam Garousi, Sanaz Bahremand, Zahra Razzaghi, Amir Hossein Rahavian, Nastaran Khalili   +8 more
doaj   +1 more source

Chemotherapy-mediated p53-dependent DNA damage response in clear cell renal cell carcinoma: role of the mTORC1/2 and hypoxia-inducible factor pathways [PDF]

, 2013
The DNA-damaging agent camptothecin (CPT) and its analogs demonstrate clinical utility for the treatment of advanced solid tumors, and CPT-based nanopharmaceuticals are currently in clinical trials for advanced kidney cancer; however, little is known ...
Ashcroft, M, Carroll, VA, Selvarajah, J, Moumen, A, Nathawat, K   +4 more
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Overexpression of TRIM2 suppresses proliferation, migration and stemness of clear cell renal cell carcinoma cells in vitro

Di-san junyi daxue xuebao, 2019
Objective To explore the effect of tripartite motif-containing protein 2 (TRIM2) on the proliferation, migration and stemness of clear cell renal clear carcinoma.
LUO Xing, LUO Jing, LIU Xin, ZHOU Tao, SUN Bishao   +4 more
doaj   +1 more source

Clinical utility of MCM2 and CD44 expression in clear cell renal cell carcinoma

Polish Journal of Pathology, 2021
Clear cell renal cell carcinoma (ccRCC) has an unpredictable clinical consequence even with the use of usual prognostic factors. To determine whether utilization of cell proliferation and cell adhesion by using MCM2 and CD44 immuno-expression could ...
Mariana F. Gayyed, Medhat M. Soliman, Maram El-Hussieny   +2 more
doaj   +1 more source

UBE2QL1 is Disrupted by a Constitutional Translocation Associated with Renal Tumor Predisposition and is a Novel Candidate Renal Tumor Suppressor Gene [PDF]

, 2013
Investigation of rare familial forms of renal cell carcinoma (RCC) has led to the identification of genes such as VHL and MET that are also implicated in the pathogenesis of sporadic RCC. In order to identify a novel candidate renal tumor suppressor gene,
Hodgson, S, Morris, Mark R., Turnell, Andrew S., Woodward, ER, Prigmore, Elena, Woodward, Emma R.; id_orcid, Wake, NC, Wake, Naomi C., Gribble, Susan M., Ricketts, Christopher J., Skytte, AB, Brown, Michael, Banks, RE, Morris, MR, Prigmore, E, Maher, ER, Woodward, Emma R., Clarke, Noel, Hodgson, Shirley, Skytte, Anne-bine, Ricketts, CJ, Turnell, AS, Brown, Michael; id_orcid, Maher, Eamonn R., Clarke, N, Banks, Rosamonde E., Gribble, SM, Brown, M, Skytte, Anne Bine, Wake, N, Clarke, Noel W, Brown, Michael D, Ricketts, C, Woodward, E, Skytte, A-B, Maher, E, Morris, M, Banks, R, Turnell, A, Gribble, S   +39 more
core   +1 more source