Results 31 to 40 of about 7,424,540 (294)

Temsirolimus for patients with metastatic renal cell carcinoma : outcomes in patients receiving temsirolimus within a compassionate use program in a tertiary referral center [PDF]

, 2014
Aim: Temsirolimus has shown efficacy as first-line treatment of patients with metastatic renal cell carcinoma and poor prognostic features. The efficacy of temsirolimus in other clinical settings, such as second-line therapy, is unclear.
Pascoe, Jennifer, Afshar, Mehran, Porfiri, Emilio, Whitmarsh, Sue, James, Nicholas D.   +4 more
core   +1 more source

Clinical utility of MCM2 and CD44 expression in clear cell renal cell carcinoma

Polish Journal of Pathology, 2021
Clear cell renal cell carcinoma (ccRCC) has an unpredictable clinical consequence even with the use of usual prognostic factors. To determine whether utilization of cell proliferation and cell adhesion by using MCM2 and CD44 immuno-expression could ...
Mariana F. Gayyed, Medhat M. Soliman, Maram El-Hussieny   +2 more
doaj   +1 more source

Risk Factors and Histopathological Features of Renal Cell Carcinoma Subtypes [PDF]

Translational Research in Urology, 2022
Introduction: Kidney cancer is currently the 9th most common cancer in men and the 14th most common in women. Renal cell carcinoma (RCC) is the most common type of kidney cancer, accounting for about 85% of all renal malignancies. It accounts for about 2%
Anahita Ansari Djafari, Babakak Javanmard, Seyyed Ali Hojjati, Saba Faraji, Maryam Garousi, Sanaz Bahremand, Zahra Razzaghi, Amir Hossein Rahavian, Nastaran Khalili   +8 more
doaj   +1 more source

UBE2QL1 is Disrupted by a Constitutional Translocation Associated with Renal Tumor Predisposition and is a Novel Candidate Renal Tumor Suppressor Gene [PDF]

, 2013
Investigation of rare familial forms of renal cell carcinoma (RCC) has led to the identification of genes such as VHL and MET that are also implicated in the pathogenesis of sporadic RCC. In order to identify a novel candidate renal tumor suppressor gene,
Hodgson, S, Morris, Mark R., Turnell, Andrew S., Woodward, ER, Prigmore, Elena, Woodward, Emma R.; id_orcid, Wake, NC, Wake, Naomi C., Gribble, Susan M., Ricketts, Christopher J., Skytte, AB, Brown, Michael, Banks, RE, Morris, MR, Prigmore, E, Maher, ER, Woodward, Emma R., Clarke, Noel, Hodgson, Shirley, Skytte, Anne-bine, Ricketts, CJ, Turnell, AS, Brown, Michael; id_orcid, Maher, Eamonn R., Clarke, N, Banks, Rosamonde E., Gribble, SM, Brown, M, Skytte, Anne Bine, Wake, N, Clarke, Noel W, Brown, Michael D, Ricketts, C, Woodward, E, Skytte, A-B, Maher, E, Morris, M, Banks, R, Turnell, A, Gribble, S   +39 more
core   +1 more source

Enhancer of zeste homolog 2 (EZH2) expression is an independent prognostic factor in renal cell carcinoma [PDF]

, 2010
Background: The enhancer of zeste homolog 2 (EZH2) gene exerts oncogene-like activities and its (over)expression has been linked to several human malignancies. Here, we studied a possible association between EZH2 expression and prognosis in patients with
Johannes Hüsing, Wagener, Nina, Hüsing Johannes, Karin Hoppe-Seyler, Hoppe-Seyler Felix, Peter Schirmacher, Hoppe-Seyler, Karin, Pfitzenmaier, Jesco, Macher-Göppinger, Stephan, Jesco Pfitzenmaier, Hohenfellner, Markus, Hüsing, Johannes, Haferkamp, Axel, Haferkamp Axel, Stephan Macher-Goeppinger, Maria Pritsch, Wagener Nina, Pritsch Maria, Axel Haferkamp, Schirmacher Peter, Nina Wagener, Hoppe-Seyler Karin, Hohenfellner Markus, Felix Hoppe-Seyler, Hoppe-Seyler, Felix, Pfitzenmaier Jesco, Macher-Goeppinger Stephan, Markus Hohenfellner, Pritsch, Maria, Schirmacher, Peter   +29 more
core   +2 more sources

Metastatic renal cell carcinoma initially presenting with hematochezia and subsequently with vaginal bleeding: a case report

BMC Urology, 2018
Background We report an unusual case of a synchronous rectal and metachronous vaginal metastatic renal cell carcinoma. Case presentation A 78-year-old woman presented with hematochezia and a colonoscopy revealed a metastatic clear-cell renal cell ...
Simon Ouellet, Audrey Binette, Alexander Nguyen, Perrine Garde-Granger, Robert Sabbagh   +4 more
doaj   +1 more source

Clear Cell Papillary Renal Cell Carcinoma in the Bilateral Native Kidneys after 2 Years of Renal Transplantation: Report of a Case and Review of the Literature

Case Reports in Transplantation, 2011
Renal transplantation increases the probability of malignant tumors by about 2–4-fold overall with a much higher rate for renal epithelial malignancy.
Zhanyong Bing, John E. Tomaszewski
doaj   +1 more source

Immunotherapy of Clear-Cell Renal-Cell Carcinoma

Cancers
Clear-cell Renal-Cell Carcinoma (ccRCC) is the most common type of renal-cell carcinoma (RCC). In many cases, RCC patients manifest the first symptoms during the advanced stage of the disease. For this reason, immunotherapy appears to be one of the dominant treatments to achieve a resolution.
Sophie Grigolo, Luis Filgueira
openaire   +2 more sources

Clear Cell Adenocarcinoma of the Ureter Similar to Clear Cell Renal Cell Carcinoma Histology

Case Reports in Urology, 2021
A 70-year-old woman was referred to our hospital with gross hematuria and diagnosed with right invasive ureteral cancer and bladder urothelial carcinoma in situ.
Kazuhiro Watanabe, Go Hasegawa, Yohei Ikeda, Noboru Hara, Tsutomu Nishiyama   +4 more
doaj   +1 more source

Quantitative proteomics in resected renal cancer tissue for biomarker discovery and profiling [PDF]

, 2014
BACKGROUND: Proteomics-based approaches for biomarker discovery are promising strategies used in cancer research. We present state-of-art label-free quantitative proteomics method to assess proteome of renal cell carcinoma (RCC) compared with noncancer ...
J T-J Huang, Bray, S E, Fleming, S., Lamont, D J, D J Lamont, Zakikhani, P, P Zakikhani, M A V Mudaliar, Atrih, A, S Fleming, Zakikhani, P., Lamont, D. J., Barton, G.; id_orcid, G Nabi, G Barton, A Atrih, Bray, S. E., Barton, G, Huang, J. T.-J.; id_orcid, Mudaliar, M. A. V., Atrih, A., Fleming, S, Nabi, G, Nabi, G., Huang, J T-J, S E Bray, Mudaliar, M A V   +26 more
core   +1 more source