Results 11 to 20 of about 8,019,599 (294)

LTB4R Promotes the Occurrence and Progression of Clear Cell Renal Cell Carcinoma (ccRCC) by Regulating the AKT/mTOR Signaling Pathway

Cells, 2022
ccRCC is highly immunogenic, yet its underlying immune-related molecular mechanisms are unknown. Leukotriene B4 Receptor 1 (LTB4R), a novel immune-related gene associated in our previous research with the prognosis of ccRCC patients, has been found in ...
Xiao Zhang, Huahui Wu, Xin Yan, Jiajun Ma, Zhao Chen   +4 more
doaj   +2 more sources

TRIM2 downregulation in clear cell renal cell carcinoma affects cell proliferation, migration, and invasion and predicts poor patients’ survival

Cancer Management and Research, 2018
Wen Xiao, Xuegang Wang, Tao Wang, Jinchun Xing Department of Urology, The First Affiliated Hospital of Xiamen University, Xiamen 361003, China Background and aim: Tripartite motif containing (TRIM) family protein has been involved in multiple ...
Xiao W, Wang X, Wang T, Xing J
doaj   +1 more source

Overview of clear cell renal cell carcinoma: from mechanisms to clinical [PDF]

Frontiers in Medicine
Clear cell renal cell carcinoma is the most common histological subtype of kidney cancer, and its development is often related to mutations in the VHL gene. Inactivation of the VHL gene leads to accumulation of HIF-2α.
Han Yang, Xingda Zhang, Qingming Ji, Xia Sheng   +3 more
doaj   +2 more sources

Clear Cell Adenocarcinoma of the Ureter Similar to Clear Cell Renal Cell Carcinoma Histology

Case Reports in Urology, 2021
A 70-year-old woman was referred to our hospital with gross hematuria and diagnosed with right invasive ureteral cancer and bladder urothelial carcinoma in situ.
Kazuhiro Watanabe, Go Hasegawa, Yohei Ikeda, Noboru Hara, Tsutomu Nishiyama   +4 more
doaj   +2 more sources

MYC pathway is activated in clear cell renal cell carcinoma and essential for proliferation of clear cell renal cell carcinoma cells

Cancer Letters, 2009
Clear cell renal cell carcinoma (ccRCC) is the major and aggressive subtype of RCC. Previously, we identified 383 differentially expressed genes by analyzing full-length cDNA libraries of ccRCC and normal kidney tissues. In this study, we applied functional network analysis to the differentially expressed genes for identifying deregulated molecular ...
Sai-Wen, Tang, Wen-Hsin, Chang, Yih-Ching, Su, Yu-Chi, Chen, Yen-Han, Lai, Pei-Tzu, Wu, Chyong-Ing, Hsu, Wei-Chou, Lin, Ming-Kuen, Lai, Jung-Yaw, Lin   +9 more
openaire   +3 more sources

Renal Clear Cell Carcinoma and Tonsil Metastasis [PDF]

Case Reports in Otolaryngology, 2013
Renal cell carcinoma is the most common renal tumor in adults. Clear cell carcinoma represents 85% of all histological subtypes. In February 2012 a 72-year-old woman came to our department due to the appearance of massive hemoptysis and pharyngodinia ...
Dario Marcotullio, Giannicola Iannella, Gian Franco Macri, Caterina Marinelli, Melissa Zelli, Giuseppe Magliulo   +5 more
doaj   +2 more sources

Clear Cell Papillary Renal Cell Carcinoma [PDF]

Archives of Pathology & Laboratory Medicine, 2019
Clear cell papillary renal cell carcinoma (ccpRCC) is a recently recognized entity and represents the fourth most common variant of renal cell carcinoma (RCC). It has unique morphologic and immunohistochemical features and demonstrates an indolent clinical behavior.
Jianping, Zhao, Eduardo, Eyzaguirre
openaire   +2 more sources

Prognostic significance of CKAP2L expression in patients with clear cell renal cell carcinoma

Frontiers in Genetics, 2023
Background: Cytoskeleton-associated protein 2-like protein (CKAP2L) is thought to promote the progression of glioma, breast cancer, and ovarian cancer. However, the role of cytoskeleton-associated protein 2-like protein in clear cell renal cell carcinoma
Zhi Liu, Jun Zhang, Deyun Shen, Xuechun Hu, Zongpan Ke, I Nyoman Ehrich Lister, Bungaran Sihombing   +6 more
doaj   +1 more source

Determinants of anti-PD-1 response and resistance in clear cell renal cell carcinoma [PDF]

, 2021
ADAPTeR is a prospective, phase II study of nivolumab (anti-PD-1) in 15 treatment-naive patients (115 multiregion tumor samples) with metastatic clear cell renal cell carcinoma (ccRCC) aiming to understand the mechanism underpinning therapeutic response.
Schnidrig, D, Sunderland, MW, Ghorani, E, Lingard, K, Rowan, A, Jamal-Hanjani, M, Litchfield, K, Turajlic, S, Becker, PD, Swanton, C, Borg, E, PEACE Consortium, Hatipoglu, E, Mahadeva, U, Xu, H, Hazell, S, Mitchison, M, Green, A, TRACERx Renal Consortium, Reading, JL, Sarker, S, Robert de Massy, M, Nicol, D, TRACERx Renal Consortium,, Falzon, M, López, JI, Edmonds, K, Carlyle, E, Mason, R, Salgado, R, Vasquez, MD, Uddin, I, Au, L, Proctor, I, Yang, WW, Quezada, SA, Spencer, C, Fotiadis, N, Shepherd, STC, Mangwende, M, Dhillon, K, Joshi, K, Lund, T, Byrne, F, Horswell, S, Beattie, G, Moore, DA, PEACE Consortium,, Furness, AJS, Puccio, I, Akarca, A, Thompson, R, Larkin, J, Chain, B, Del Rosario, L, Fendler, A, Pickering, L, Kassiotis, G, Marafioti, T, Attig, J   +59 more
core   +1 more source

Genetics and Tumor Microenvironment of Renal Cell Carcinoma

Société Internationale d’Urologie Journal, 2022
Renal cell carcinoma is a diverse group of diseases that can be distinguished by distinct histopathologic and genomic features. In this comprehensive review, we highlight recent advancements in our understanding of the genetic and microenvironmental ...
Sari Khaleel, Christopher Ricketts, W. Marston Linehan, Mark Ball, Brandon Manley, Samra Turajilic, James Brugarolas, Ari Hakimi   +7 more
doaj   +1 more source