Results 61 to 70 of about 337,050 (372)

Metastatic renal cell carcinoma initially presenting with hematochezia and subsequently with vaginal bleeding: a case report

BMC Urology, 2018
Background We report an unusual case of a synchronous rectal and metachronous vaginal metastatic renal cell carcinoma. Case presentation A 78-year-old woman presented with hematochezia and a colonoscopy revealed a metastatic clear-cell renal cell ...
Simon Ouellet, Audrey Binette, Alexander Nguyen, Perrine Garde-Granger, Robert Sabbagh   +4 more
doaj   +1 more source

Downregulation of CIP2A inhibits cancer cell proliferation and vascularization in renal clear cell carcinoma

Biomedical Papers, 2020
Background: CIP2A has been proved to play a role as an oncogene in various types of malignancies while its functionality in renal clear cell carcinoma has not been investigated.
Hui Gao, Yuqiao Li, Tao Lin, Yan Cheng, Yunbo Ma   +4 more
doaj   +1 more source

Single-cell multiomics analysis reveals regulatory programs in clear cell renal cell carcinoma

Cell Discovery, 2022
The clear cell renal cell carcinoma (ccRCC) microenvironment consists of many different cell types and structural components that play critical roles in cancer progression and drug resistance, but the cellular architecture and underlying gene regulatory ...
Zhilin Long, Chengfang Sun, Min Tang, Yin Wang, Jiayan Ma, Jichuan Yu, Jingchao Wei, Jianzhu Ma, Bohan Wang, Q. Xie, J. Wen   +10 more
semanticscholar   +1 more source

Secreted miR-210-3p as non-invasive biomarker in clear cell renal cell carcinoma [PDF]

, 2017
The most common subtype of renal cell carcinoma (RCC) is clear cell RCC (ccRCC). It accounts for 70-80% of all renal malignancies representing the third most common urological cancer after prostate and bladder cancer.
Carbone, Antonio, Costantini, Manuela, DI CARLO, Angelina, Fazi, Francesco, Gallucci, Michele, Marigliano, Chiara, Palleschi, Giovanni, Pastore, ANTONIO LUIGI, Petrozza, Vincenzo, Porta, Natale, Ricci, Serena, Simone, Giuseppe, Tito, Claudia   +12 more
core   +2 more sources

Histological Tracking into the Third Dimension: Evolution of Early Tumorigenesis in VHL Kidney

Journal of Kidney Cancer and VHL, 2021
Using a novel three-dimensional (3D) approach, we tracked histological changes to elucidate the earliest stages of renal clear cell neoplasia in normal kidney tissue of patients with von Hippel-Lindau (VHL) disease.
Mayyan Mubarak, Nayef Al-Gharaibeh, Samuel Sommaruga, Jie Li, Alexander Oliver Vortmeyer   +4 more
doaj   +3 more sources

Characterization of renal artery variation in patients with clear cell renal cell carcinoma and the predictive value of accessory renal artery in pathological grading of renal cell carcinoma: a retrospective and observational study

BMC Cancer, 2023
Objective To explore the characteristics of renal artery variation in patients with renal cell carcinoma and to evaluate the predicting value of accessory renal artery in the pathological grading of renal cell carcinoma.
Dingyang Lv, Huiyu Zhou, Fan Cui, Jie Wen, Weibing Shuang   +4 more
doaj   +1 more source

Evaluation of the Relative Enhancement Ratio and Morphologic Findings on Biphasic CT to Differentiate Clear Cell and Non-Clear Cell Renal Cell Carcinoma

Siriraj Medical Journal, 2016
Objective: To differentiate clear cell and non-clear cell renal cell carcinoma (RCC) using enhancement pattern, relative enhancement ratio and associated findings on CT scan.
Nithida Na Songkhla
doaj   +2 more sources

Clear Cell Papillary Renal Cell Carcinoma in the Bilateral Native Kidneys after 2 Years of Renal Transplantation: Report of a Case and Review of the Literature

Case Reports in Transplantation, 2011
Renal transplantation increases the probability of malignant tumors by about 2–4-fold overall with a much higher rate for renal epithelial malignancy.
Zhanyong Bing, John E. Tomaszewski
doaj   +1 more source

HIF-1α and HIF-2α differently regulate tumour development and inflammation of clear cell renal cell carcinoma in mice

Nature Communications, 2020
Mutational inactivation of VHL is the earliest genetic event in the majority of clear cell renal cell carcinomas (ccRCC), leading to accumulation of the HIF-1α and HIF-2α transcription factors.
Rouven Hoefflin, Sabine Harlander, Silvia Schäfer, Patrick Metzger, F. Kuo, Désirée Schönenberger, Mojca Adlesic, Asin Peighambari, Philipp Seidel, Chia-yi Chen, Miguel Consenza-Contreras, A. Jud, B. Lahrmann, N. Grabe, D. Heide, F. Uhl, T. Chan, J. Duyster, R. Zeiser, C. Schell, M. Heikenwalder, O. Schilling, O. Schilling, A. Hakimi, M. Boerries, M. Boerries, I. Frew   +26 more
semanticscholar   +1 more source

Decoding the multicellular ecosystem of vena caval tumor thrombus in clear cell renal cell carcinoma by single-cell RNA sequencing

Genome Biology, 2022
Background Vascular invasion with tumor thrombus frequently occurs in advanced renal cell carcinoma (RCC). Thrombectomy is one of the most challenging surgeries with high rate of perioperative morbidity and mortality.
Yue Shi, Qi Zhang, H. Bi, Minqiang Lu, Ye-Hui Tan, D. Zou, L. Ge, Zhigang Chen, Cheng Liu, W. Ci, Lulin Ma   +10 more
semanticscholar   +1 more source