Results 91 to 100 of about 1,613,704 (299)

Increased branching and sialylation of N-linked glycans correlate with an improved pharmacokinetic profile for BAY 81–8973 compared with other full-length rFVIII products

open access: yesDrug Design, Development and Therapy, 2019
John M Teare,1 David S Kates,1 Anita Shah,2 Stephen Garger1 1Biological Development, Bayer US LLC Pharmaceuticals, Berkeley, CA, USA; 2Pharmacokinetics Pharmacodynamics Hematology, Bayer US LLC Pharmaceuticals, Whippany, NJ, USA Background: BAY 81 ...
Teare JM, Kates DS, Shah A, Garger S
doaj  

Prolonged Zika Virus RNA Detection in Semen of Immunosuppressed Patient

open access: yesEmerging Infectious Diseases, 2019
Zika virus RNA has been detected in semen samples collected 900 days, in a patient with immunosuppression.
Christina Petridou   +10 more
doaj   +1 more source

Railway freight transport and logistics: Methods for relief, algorithms for verification and proposals for the adjustment of tunnel inner surfaces [PDF]

open access: yes, 2018
In Europe, the attention to efficiency and safety of international railway freight transport has grown in recent years and this has drawn attention to the importance of verifying the clearance between vehicle and lining, mostly when different and ...
Ferraro, Ricardo   +3 more
core   +1 more source

An upstream open reading frame regulates expression of the mitochondrial protein Slm35 and mitophagy flux

open access: yesFEBS Letters, EarlyView.
This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva   +5 more
wiley   +1 more source

In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS

open access: yesFEBS Letters, EarlyView.
We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka   +11 more
wiley   +1 more source

Measured and estimated glomerular filtration rate. Numerous methods of measurements (Part I)

open access: yesRevista de Nefrología, Diálisis y Trasplante, 2017
The loss of half the renal mass does not necessarily imply half the Glomerular Filtration Rate (GFR), meaning that there is not an exact correlation between renal mass reduction and renal function loss.
Jaime Pérez Loredo   +2 more
doaj  

Cell wall target fragment discovery using a low‐cost, minimal fragment library

open access: yesFEBS Letters, EarlyView.
LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan   +5 more
wiley   +1 more source

SEED QUALITY PARAMETERS OF PURPLE HORSEMINT FOR ELABORATION OF STANDART

open access: yesОвощи России, 2016
Purple horsemint (Monarda citriodora L.) is a perennial plant belonging to Lamiaceae family and being cultivated as aromatic and ornamental crop in many countries of Europe and America. Last years this plant actively gains popularity among gardeners.
L. V. Pavlov   +4 more
doaj   +1 more source

High stiffness seals for rotor critical speed control [PDF]

open access: yes
An annular seal is analyzed in which the inlet clearance is larger than the outlet clearance; the flow path may be either stepped or tapered. This design produces radial stiffness 1.7 to 14 times that of a constant clearance seal having the same minimum ...
Fleming, D. P.
core   +1 more source

Advance, Spring 2011 [PDF]

open access: yes, 2011
News from the San Jose State University Record Clearance ...
San Jose State University, Department of Justice Studies,
core   +1 more source

Home - About - Disclaimer - Privacy