Results 251 to 260 of about 1,663,252 (327)

ICG clearance as an indicator of augmented hepatic clearance and subtherapeutic drug concentrations in septic patients. [PDF]

BMC Anesthesiol
Xu Y, Wu X, Yan M, Yu W, Dong D, Qu C, Liu N.   +6 more
europepmc   +1 more source

ATG4B is required for mTORC1‐mediated anabolic activity and is associated with clinical outcomes in non‐small cell lung cancer

FEBS Open Bio, EarlyView.
The relationship between anabolic and catabolic processes governing lung cancer cell growth is nuanced. We show that ATG4B, an autophagy regulator, is elevated in lung cancer and that high ATG4B is associated with worse patient outcomes. Targeting ATG4B in cells reduces growth, protein synthesis, and mTORC1 activity, demonstrating a new relationship ...
Patrick J. Ryan, Bethany C. Guerra, Selina Uranga, Jessica M. Cardin, Steven E. Riechman, Mariana Janini Gomes, James D. Fluckey   +6 more
wiley   +1 more source

Blast Clearance Dynamics and Time to Response Across <i>IDH1-</i> and <i>IDH2</i>-Mutated AML. [PDF]

EJHaem
Najeeb MS, Alkabbani O, He R, Jevremovic D, Greipp PT, Matin A, Hefazi M, Mangaonkar A, Patnaik M, Gangat N, Hogan WJ, Litzow MR, Yi CYA, Foran JM, Alkhateeb HB, Shah M, Begna K, Kewan T, Saliba AN, Al-Kali A.   +19 more
europepmc   +1 more source

Fibrin Deposition and Clearance in Chronic Granulomatous Inflammation: Correlation with T-Cell Function and Proteinase Inhibitor Activity in Tissue

, 1979
Seiichi Izaki, Sanford Goldstein, Kimie Fukuyama, William L. Epstein   +3 more
openalex   +1 more source

Dietary nitrate and nitrite protect against doxorubicin‐induced cardiac fibrosis and oxidative protein damage in tumor‐bearing mice

FEBS Open Bio, EarlyView.
Chemotherapies such as doxorubicin can have toxic effects on healthy cardiovascular/heart tissue. Following up on a doxorubicin toxicity study in mice without tumors where nitrate water was cardioprotective (lessened toxicity), this study with tumor‐bearing mice undergoing doxorubicin treatment showed no negative effect of nitrate and nitrite on drug ...
Rama D. Yammani, Xiaofei Chen, Nildris Cruz‐Diaz, Xuewei Zhu, Swati Basu, Daniel B. Kim‐Shapiro, David R. Soto‐Pantoja, Leslie B. Poole   +7 more
wiley   +1 more source

Functions of the basal lamina and ApoE in cerebral amyloid angiopathy. [PDF]

Fluids Barriers CNS
Juan-Palencia A, Yao Y.
europepmc   +1 more source

Diabetes‐induced vascular calcification is associated with low pyrophosphate and its oral supplementation prevents calcification in diabetic mice

FEBS Open Bio, EarlyView.
Induction of diabetes in three different mouse strains uniformly resulted in an increase in TNAP activity and a reduction in pyrophosphate (PPi) in the circulation. Inhibition of TNAP restored plasma PPi. Diabetes‐induced calcification in the media layer of the aorta was detected only in the Abcc6−/− strain, which is predisposed to ectopic ...
Krisztina Fülöp, Eszter Kozák, Natália Tőkési, Lilian Kocsis, Anikó Kelemen, Zsuzsanna Geszti, Adriána Kutás, Mariann Harangi, Ágnes Diószegi, Zsolt Rapi, József Balla, Olivier Le Saux, András Váradi, Viola Pomozi   +13 more
wiley   +1 more source