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Journal of Veterinary Pharmacology and Therapeutics, 2004
Plasma (total, systemic…) clearance is determined by all the individual metabolizing/eliminating organ clearances and involves mainly liver and kidney clearances. Plasma clearance (a volume per time, i.e. a flow) expresses the overall ability of the body to eliminate a drug by scaling the drug elimination rate (amount per time) by the corresponding ...
Toutain, Pierre-Louis +1 more
openaire +4 more sources
Plasma (total, systemic…) clearance is determined by all the individual metabolizing/eliminating organ clearances and involves mainly liver and kidney clearances. Plasma clearance (a volume per time, i.e. a flow) expresses the overall ability of the body to eliminate a drug by scaling the drug elimination rate (amount per time) by the corresponding ...
Toutain, Pierre-Louis +1 more
openaire +4 more sources
Respiration, 1991
The lungs possess several mechanisms for cleansing themselves from locally produced biological debris and inhaled, deposited soluble and insoluble materials. Insoluble particles deposited on the conducting, ciliated airways will be primarily removed by mucociliary clearance, over a period of several hours, with cough acting as a back-up clearance ...
openaire +2 more sources
The lungs possess several mechanisms for cleansing themselves from locally produced biological debris and inhaled, deposited soluble and insoluble materials. Insoluble particles deposited on the conducting, ciliated airways will be primarily removed by mucociliary clearance, over a period of several hours, with cough acting as a back-up clearance ...
openaire +2 more sources
European Journal of Nuclear Medicine, 1994
The aim of this study was to establish reference values for mucociliary clearance and mucociliary clearance reserve capacity as determined by beta 2-adrenergic agonist-induced increase in mucociliary clearance. We studied 62 healthy females (n = 33) and males (n = 29). Their ages ranged evenly between 18 and 84 years.
J, Mortensen +3 more
openaire +2 more sources
The aim of this study was to establish reference values for mucociliary clearance and mucociliary clearance reserve capacity as determined by beta 2-adrenergic agonist-induced increase in mucociliary clearance. We studied 62 healthy females (n = 33) and males (n = 29). Their ages ranged evenly between 18 and 84 years.
J, Mortensen +3 more
openaire +2 more sources