Results 231 to 240 of about 1,284,621 (297)

PDCoV NSP5 cleaves the selective autophagy receptor CCDC50 to disrupt autophagic degradation of the viral envelope protein. [PDF]

mBio
Li K, Wei H, Zhao K, Chen D, Sun Y, Zhou P, Jin H, Jongkaewwattana A, Suolang S, Wang D, Zhou H, Luo R.   +11 more
europepmc   +1 more source

Dual‐Peptide Nanoplatform: Mesoporous Silica Nanoparticles Functionalized With a Cell‐Penetrating Peptide and Loaded With Rationally Designed Antimicrobial Peptides for Tuberculosis Therapy

Advanced Healthcare Materials, EarlyView.
Machine learning–guided engineering of a plectasin‐derived peptide yields DC05, a potent antimycobacterial candidate. Encapsulation into tuftsin‐functionalized mesoporous silica nanoparticles enhances intracellular delivery, stability, and activity against Mycobacterium tuberculosis while maintaining low cytotoxicity and minimal hemolysis. The combined
Christian S. Carnero Canales, Cesar Augusto Roque‐Borda, Ana Carolina Cerqueira Negri, Oswaldo Ramirez Delgado, Letícia Oliveira Catarin Nunes, Flávia Aparecida Resende, Hernane Barud, Norival Alves Santos‐Filho, Saulo Santesso Garrido, Karen Cristina Oliveira, Alexandra Ivo de Medeiros, Rafael Miguel Sábio, Fernando Rogério Pavan   +12 more
wiley   +1 more source

AcrVA3 Is a Double Strand DNA-Cleaving Anti-CRISPR That Indirectly Inhibits Cas12. [PDF]

FASEB J
Han JH, Kang YJ, Lee SY, Jin HB, Lee CS, Park HH.   +5 more
europepmc   +1 more source

Engineering Extracellular Vesicle Production Through Magnetic Ion Channel Activation for Bone Regeneration

Advanced Healthcare Materials, EarlyView.
Magnetic Ion Channel Activation (MICA) enables remote stimulation of mechanosensitive ion channels using functionalised magnetic nanoparticles, enhancing extracellular vesicle (EV) biogenesis is pre‐osteoblasts. MICA desrived EVs exhibit typical nano‐vesicular characteristics but display superior pro‐osteogeneic activity, promoting mesenchymal stem ...
Afeesh Rajan Unnithan, Kenny Man, Kritika, Lee A. Gethings, Christopher J. Hughes, Alicia Keenan, Liam Heaney, Sophie C. Cox, Owen G. Davies, Alicia J. El Haj   +9 more
wiley   +1 more source

Totipotency and high plasticity in an embryo with an invariant, fate-specifying cleavage program. [PDF]

Curr Biol
Rock AQ, Srivastava M.
europepmc   +1 more source

Enterovirus-induced cleavage of Mitofusin 2 generates mitophagosomes for enveloped virion release. [PDF]

Sci Adv
Jassey A, Paudel B, Wagner MA, Pollack N, Cheng IT, Godoy-Ruiz R, Weber DJ, Jackson WT.   +7 more
europepmc   +1 more source

Functional decoupling of crRNA enables customizable CRISPR diagnostics. [PDF]

Nucleic Acids Res
Park H, Yun J, Lee K, Kim JH, Park JH, Park YJ, Park JH, Lee H, Kim MG.   +8 more
europepmc   +1 more source

The effect of laser-assisted hatching on clinical outcomes of frozen-thawed embryo transfer at different embryo ages. [PDF]

Eur J Obstet Gynecol Reprod Biol X
Ou MM, Liao BY, Chen XH, Hu LL, Lu YL, Qin HM, Wang JL, Wei YX.   +7 more
europepmc   +1 more source

Caspase-mediated DDX46 cleavage unchains antiviral immunity. [PDF]

mBio
Liu Y, Liu Z, Ou X, Zhao F, Wang J, Qu Y, Qiu X, Liao Y, Tan L, Song C, Ding C, Sun Y.   +11 more
europepmc   +1 more source