Results 71 to 80 of about 9,193 (154)

cis-Clerodane type diterpenes from Cistus monspeliensis

, 2003
The aerial parts of Cistus monspeliensis yielded 11 cis-clerodane type diterpenes. Five of these, 3, 4, 8, 9, and 10, are new compounds. Their structures have been elucidated on the basis of their spectral data (FABMS, 1D and 2D NMR)
Mitakou, S., Kalpoutzakis, E., Aligiannis, N., Skaltsounis, A.-L.   +3 more
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Novel Cytotoxic Diterpenes from Casearia arborea

, 2016
Cytotoxicity-guided fractionation of the dichloromethane−methanol extract of the roots of Casearia arborea yielded five novel clerodane diterpenes, casearborins A−E (1−5), as well as cucurbitacin B.
Robert H. Shoemaker (146228), Kate L. McCall (3062049), Delbert L. Herald (2196577), John A. Beutler (7678), Tanya Johnson (3062052), Kathryn Herbert (3062046), Michael R. Boyd (2709340), George R. Pettit (1316853)   +7 more
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Chemical variability between different organs of the medicinal plant Casearia sylvestris

Revista de Ciências Farmacêuticas Básica e Aplicada, 2020
The phytochemical profile of essential oils and extracts from Casearia sylvestris leaves, flowers and fruits have been investigated here. Leaf and flower extracts were prepared by sonication and analyzed by thin-layer chromatography and high-performance ...
Flávio Alexandre Carvalho, Polyanna Pereira Aguilar, Fernando Bombarda Oda, Helena Sayuri Uchina, Aristeu Gomes Tininis, Eduardo José Crevelin, Antônio Eduardo Miller Crotti, André Gonzaga dos Santos   +7 more
doaj  

Clerodane Diterpenes from Casearia arguta That Act As Synergistic TRAIL Sensitizers

, 2016
Casearia arguta was investigated as part of the ongoing search for synergistic TRAIL (tumor necrosis factor-α-related apoptosis-inducing ligand) sensitizers.
Thomas J. Sayers (613029), Cheryl L. Thomas (30987), James B. McMahon (7677), Emily L. Whitson (1264857), Curtis J. Henrich (131182), Tawnya C. McKee (2039704)   +5 more
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Bioactive Clerodane Diterpenes from Roots of Carex distachya

, 2010
Two new clerodane diterpenes were isolated from roots of Carex distachya Desf., a perennial plant widely distributed in the coastal area of the Mediterranean basin.
A. IZZO, D'ABROSCA, Brigida, G. DANGELO, FIORENTINO, Antonio, MONACO, Pietro, PACIFICO, Severina   +5 more
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Lignans and diterpenes of three Aristolochia species

, 1988
Phytochemical examination of Aristolochia cymbifera, A. esperanzae and A. galeata led to the isolation of furofuran and dibenzylbutyrolactone type lignans, as well as of clerodane and ent-labdane type diterpenes.
Vanderlan da S. Bolzani, Bolzani, Vanderlan da Silva [UNESP], Bolzani, Vanderlan da Silva, Lopes, Lucia M.X. [UNESP], Lucia M.X. Lopes, Lopes, Lucia M.X., Lopes, LMX   +6 more
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Allosteric modulation of laeviganoid-based clerodane diterpenes derivatives in muscarinic acetylcholine M1 receptor against tinnitus: a structure-based virtual screening approach

Future Journal of Pharmaceutical Sciences
Background Chronic tinnitus is a complication that affects the central nervous system, specifically the auditory cortex, causing a phantom perception of sounds and noises without any external acoustic stimulus.
Jacilene Silva, Matheus Nunes da Rocha, Victor Moreira de Oliveira, Caio Henrique Alexandre Roberto, Francisco Nithael Melo Lúcio, Márcia Machado Marinho, Hélcio Silva dos Santos, Emmanuel Silva Marinho   +7 more
doaj   +1 more source

A New ent-Clerodane Diterpene from Hymenaea courbaril var. altissima

Journal of the Brazilian Chemical Society, 2002
A new ent-clerodane and two known ent-labdanes were isolated from the barks of Hymenaea courbaril var. altissima (Ducke). The new diterpene was identified, after esterification with diazomethane, as methyl (-)-(5R,8S,9S,10R)-clerod-3-en-15-oate and known
Nogueira Raquel T., Giacomini Rosana A., Shepherd George J., Imamura Paulo M.   +3 more
doaj  

Promising Effects of Casearins in Tumor-Bearing Mice and Antinociceptive Action against Oncologic Pain: Molecular Docking and In Vivo Findings

Pharmaceuticals
Safer analgesic drugs remain a hard challenge because of cardiovascular and/or gastrointestinal toxicity, mainly. So, this study evaluated in vivo the antiproliferative actions of a fraction with casearins (FC) from Casearia sylvestris leaves against ...
Jurandy do Nascimento Silva, José Ivo Araújo Beserra Filho, Boris Timah Acha, Fernanda Regina de Castro Almeida, Emanuelle Karine Frota Batista, Valdenizia Rodrigues Silva, Larissa Mendes Bomfim, Milena Botelho Pereira Soares, Daniel Pereira Bezerra, André Gonzaga dos Santos, Francisco das Chagas Pereira de Andrade, Anderson Nogueira Mendes, Daniel Dias Rufino Arcanjo, Paulo Michel Pinheiro Ferreira   +13 more
doaj   +1 more source

Estudo de propriedades químicas, estruturais e biológicas da espécie vegetal Croton urucurana [PDF]

, 2009
Dissertação (mestrado) - Universidade Federal de Santa Catarina, Centro de Ciências da Saúde. Programa de Pos-Graduação em QuímicaCroton urucurana é uma árvore, pertencente a família Euphorbiaceae, usada na medicina popular no tratamento de dor ...
Zuchinalli, Analice
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