Anti-Inflammatory and Cytotoxic Activities of Clerodane-Type Diterpenes [PDF]
Molecules, 2023 The secondary metabolites of clerodane diterpenoids have been found in several plant species from various families and in other organisms. In this review, we included articles on clerodanes and neo-clerodanes with cytotoxic or anti-inflammatory activity ...
Rubria Marlen Martínez-Casares +5 more
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Flavonoids and Acid-Hydrolysis derivatives of Neo-Clerodane diterpenes from Teucrium flavum subsp. glaucum as inhibitors of the HIV-1 reverse transcriptase–associated RNase H function [PDF]
Journal of Enzyme Inhibition and Medicinal Chemistry, 2021 Bioassay-guided fractionation of the ethyl acetate extract from Teucrium flavum subsp. glaucum, endowed with inhibitory activity towards the HIV-1 reverse transcriptase–associated RNase H function, led to the isolation of salvigenin (1), cirsimaritin (2)
Benedetta Fois +8 more
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Modular total syntheses of trans-clerodanes and sesquiterpene (hydro)quinones via tail-to-head cyclization and reductive coupling strategies [PDF]
Nature Communications, 2022 trans-Clerodanes and sesquiterpene (hydro)quinones are different types of natural products featuring the same trans-decalin core. Here, the authors report a modular synthetic route to this family by tail-to-head cyclization and reductive coupling ...
Wenming Zhu +3 more
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A Review on the Ethnopharmacology and Phytochemistry of the Neotropical Sages (Salvia Subgenus Calosphace; Lamiaceae) Emphasizing Mexican Species [PDF]
Frontiers in Pharmacology, 2022 Salvia is the most diverse genus within the mint family (Lamiaceae), many of its species are well-known due to their medicinal and culinary uses. Most of the ethnopharmacological and phytochemical studies on Salvia are centred on species from the ...
Nancy Ortiz-Mendoza +5 more
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Microbial Transformation of neo-Clerodane Diterpenoid, Scutebarbatine F, by Streptomyces sp. CPCC 205437 [PDF]
Frontiers in Microbiology, 2021 Biotransformation of the neo-clerodane diterpene, scutebarbatine F (1), by Streptomyces sp. CPCC 205437 was investigated for the first time, which led to the isolation of nine new metabolites, scutebarbatine F1–F9 (2–10). Their structures were determined
Dewu Zhang +8 more
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Diterpenes with Abietane and Clerodane Skeletons from the Mexican Salvia Species as Potential Bioactive Compounds [PDF]
MoleculesSalvia (Lamiaceae) is Mexico’s most diverse and widely distributed genus. It represents an important natural resource for the country, with approximately 310 species belonging to the subgenera Calosphace, Audibertia, and Heterosphace.
Nancy Ortiz-Mendoza +9 more
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Activity of Ajuga iva Extracts Against the African Cotton Leafworm Spodoptera littoralis [PDF]
Insects, 2020 Control of the crop pest African cotton leafworm, Spodoptera littoralis (Boisduval), by chemical insecticides has led to serious resistance problems. Ajuga plants contain phytoecdysteroids (arthropod steroid hormone analogs regulating metamorphosis) and ...
Leena Taha-Salaime +6 more
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Chemical Fractionation Joint to In-Mixture NMR Analysis for Avoiding the Hepatotoxicity of Teucrium chamaedrys L. subsp. chamaedrys [PDF]
Biomolecules, 2021 Dietary supplements based on Teucrium chamaedrys L. subsp. chamaedrys aerial parts were banned, due to the hepatotoxicity of furan-containing neo-clerodane constituents.
Simona Piccolella +5 more
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Ent–Clerodane Diterpenoid Inhibitors of Glucose-6-phosphatase from Croton guatemalensis Lotsy [PDF]
PlantsThe Croton genus includes a diverse group of plants with remarkable potential in natural products research, particularly due to their bioactive compounds with hypoglycemic and phytochemical significance.
Sonia Marlen Escandón-Rivera +4 more
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Modified Clerodanes from the Essential Oil of Dodonea viscosa Leaves [PDF]
Molecules, 2020 Dodonea viscosa (L.) Jacq from Reunion Island (Indian Ocean) was investigated for its leaf essential oil composition. The plant was extracted by hydrodistillation and its essential oil analysed by gas chromatography coupled to mass spectrometry.
Arnaud Marvilliers +7 more
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