Results 41 to 50 of about 463 (171)

Diterpene Lactones with Labdane, Halimane and Clerodane Frameworks [PDF]

Natural Product Communications, 2011
The labdane, halimane and clerodane type diterpenoids are compounds that have been isolated in plants of several families. These molecules and their derivatives with a lactone group on the side chain or on the decaline system, have a great interest because of their biological properties as insect antifeedant, antiviral, cytotoxic and trypanocidal.
Lúcia, Silva, Arlindo C, Gomes, Jesus M L, Rodilla   +2 more
openaire   +2 more sources

Orthoquinone, Cyclic, and Acyclic α‐Diketone Natural Products: From Food Applications to Pharmacotherapy

Phytochemicals in Food and Medicine, Volume 1, Issue 1, March 2026.
The orthoquinone metabolites from plants have antimicrobial, antioxidant, antiviral, cytotoxic, and anti‐inflammatory effects. ABSTRACT The structural diversity of natural products is vast and fascinating, and they have been recognized as an enormously diverse source of new lead compounds.
Hidayat Hussain, Daijie Wang, Satyajit D. Sarker, Lutfun Nahar, Nilufar Z. Mamadalieva, Jianbo Xiao   +5 more
wiley   +1 more source

Kerlinic Acid Preserves the Furan Moiety in Regio- and Diastereoselective Oxidations Giving Beta-Lactones and Oxirane Derivatives

Reactions
Strategic scaffolds in molecules increase the possibility of obtaining derivatives with potential uses in scientific and industrial areas. The regio- and stereoselective reactions can be considered to gain these tactical motifs.
Eva E. Soto-Guzmán, Antonio J. Oliveros-Ortiz, Armando Talavera-Alemán, Mónica A. Calderón-Oropeza, Gabriela Rodríguez-García, Brenda Y. Bedolla-García, Mario A. Gómez-Hurtado, Carlos M. Cerda-García-Rojas, Jérôme Marrot, Christine Thomassigny, Rosa E. del Río   +10 more
doaj   +1 more source

Virtual Screening of Phytochemicals From Medicinal Plants as Promising PDE5 Inhibitors Against Erectile Dysfunction

Food Science &Nutrition, Volume 14, Issue 2, February 2026.
Phytochemicals from Algerian medicinal plants were virtually screened as potential phosphodiesterase‐5 (PDE5) inhibitors for erectile dysfunction therapy. Drug‐likeness and toxicity analyses identified catechin, ellagic acid, and rosmarinic acid as safe, bioavailable candidates.
Farouk Boudou, Alaeddine Berkane, Amal Belakredar, Ahcene Keziz, Huda Alsaeedi, Brian A. Murray, Mikhael Bechelany, Ahmed Barhoum   +7 more
wiley   +1 more source

Studies towards the total synthesis of insect antifeedant clerodanes [PDF]

, 1989
An approach towards the total synthesis of insect antifeedant clerodanes is described in this thesis.In chapter 1 the structure, nomenclature, occurrence, biosynthesis and physiological activities of the clerodanes are described.
Vader, J.
core  

Diterpenoids of terrestrial origin

, 2017
This review covers the isolation and chemistry of diterpenoids from terrestrial as opposed to marine sources and includes labdanes, clerodanes, abietanes, pimaranes, kauranes, cembranes and their cyclization products.
James R. Hanson
core   +1 more source

The PI3K Inhibitor HCD Promotes Caspase Activation in Head and Neck Squamous Cells by Upregulating the Extrinsic and Intrinsic Apoptosis Pathways

Journal of Oral Pathology &Medicine, Volume 55, Issue 1, Page 61-72, January 2026.
ABSTRACT Background 16‐hydroxycleroda‐3,13‐dien‐15,16‐olide (HCD), a compound isolated from Polyalthia longifolia var. pendula, has been identified as a PI3K inhibitor. P. longifolia var. pendula is recognized for its diverse pharmacological properties, including antimicrobial, hypotensive, anti‐inflammatory, and cytotoxic activities.
Leong‐Perng Chan, Ya‐Ping Tseng, Hui‐Ching Wang, Chen‐Yu Chien, Che‐Wei Wu, Ling‐Feng Wang, Tung‐Wen Yen, Po‐Chun Wang, Chih‐Chuang Liaw, Chia‐Hua Liang   +9 more
wiley   +1 more source

Friedolabdanes and other constituents from chilean Haplopappus species [PDF]

, 1991
From the aerial parts of Haplopappus pulchellus two new labdanes and six friedolabdanes were isolated while H. arbutoides afforded in addition to known labdanes five new ones, two clerodanes and a cyperone derivative.
Zdero, C., Niemeyer, H. M., C. Zdero, F. Bohlmann, Bohlmann, F., H.M. Niemeyer   +5 more
core   +1 more source

Exploring the Antiproliferative Activity of Flavolignans From the Leaves of Casearia arborea (Salicaceae)

Chemistry &Biodiversity, Volume 22, Issue 12, December 2025.
ABSTRACT The Casearia genus (Salicaceae) is well known as a source of natural antitumor prototypes, as described for clerodane diterpenes. In this way, the dichloromethane phase from leaves of Casearia arborea was phytochemically evaluated in liquid chromatography coupled to high‐resolution mass spectrometry, furnishing flavonoid, flavolignan, and ...
Augusto L. Santos, Mariana T. Rodrigues, Ana Paula Michelli, Rodrigo E. Tamura, Ileana G. S. de Rubió, Marisi G. Soares, Marcelo J. P. Ferreira, Patricia Sartorelli   +7 more
wiley   +1 more source

Eperua oleifera Ducke (Fabaceae) Oilresin Chemical Composition and the Isolation of a Natural Diterpenic Acid Methyl Ester

Chemistry &Biodiversity, Volume 22, Issue 12, December 2025.
Eperua oleifera (Fabaceae) oilresin presents not only diterpenic acids, but also diterpenic acid methyl ester. ABSTRACT Eperua oleifera Ducke, commonly known as “copaíba‐jacaré,” produces oilresins traditionally used in folk medicine for wound healing and as antifungal and antibacterial agents, similar to those of Copaifera species.
Rayssa Ribeiro, Henrique M. G. Pereira, Alvicler Magalhães, Fernando Hallwass, Monica C. Padilha, Valdir F. Veiga‐Junior   +5 more
wiley   +1 more source