Results 1 to 10 of about 2,528 (212)

Grewiifopenes A–K, bioactive clerodane diterpenoids from Casearia grewiifolia Vent. [PDF]

Natural Products and Bioprospecting
Eleven novel clerodane-type diterpenoids, grewiifopenes A–K (1–4 and 12–18), along with nine known compounds (5–11, 19, and 20) were purified from the dichloromethane extract of the twigs and stems of Casearia grewiifolia Vent. (Salicaceae).
Phanruethai Pailee, Paratchata Batsomboon, Wiriya Yaosanit, Theerawat Thananthaisong, Chulabhorn Mahidol, Poonsakdi Ploypradith, Nanthawan Reuk-ngam, Panita Khlaychan, Supanna Techasakul, Somsak Ruchirawat, Vilailak Prachyawarakorn   +10 more
doaj   +3 more sources

Clerodane diterpenoids with anti-inflammatory activity from the tuberous root of Paratinospora sagittata (Oliv.) Wei Wang [PDF]

Frontiers in Pharmacology
Seven novel clerodane diterpenoids, designated tinotanoids I–O (1−7), were isolated from the tuberous roots of Paratinospora sagittata (Oliv.) Wei Wang [syn.: Tinospora sagittata var. yunnanensis (S.Y.Hu) H.S.Lo; Menispermaceae].
Hailin Li, Jing Liu, Chuhong Fang, Shanglei Ning   +3 more
doaj   +2 more sources

Ent–Clerodane Diterpenoid Inhibitors of Glucose-6-phosphatase from Croton guatemalensis Lotsy [PDF]

Plants
The Croton genus includes a diverse group of plants with remarkable potential in natural products research, particularly due to their bioactive compounds with hypoglycemic and phytochemical significance.
Sonia Marlen Escandón-Rivera, Adolfo Andrade-Cetto, Daniel Genaro Rosas-Ramírez, Gerardo Mata-Torres, Roberto Arreguín-Espinosa   +4 more
doaj   +2 more sources

Novel Aporphine- and Proaporphine–Clerodane Hybrids Identified from the Barks of Taiwanese Polyalthia longifolia (Sonn.) Thwaites var. pendula with Strong Anti-DENV2 Activity

Pharmaceuticals, 2022
Hybrid natural products produced via mixed biosynthetic pathways are unique and often surprise one with unexpected medicinal properties in addition to their fascinating structural complexity/diversity.
I-Wen Lo, Geng-You Liao, Jin-Ching Lee, Chi-I Chang, Yang-Chang Wu, Yen-Yu Chen, Shang-Pin Liu, Huey-Jen Su, Chih-I Liu, Chia-Yi Kuo, Zheng-Yu Lin, Tsung-Lin Li, Yun-Sheng Lin, Chia-Ching Liaw   +13 more
doaj   +1 more source

Anti-Inflammatory and Cytotoxic Activities of Clerodane-Type Diterpenes

Molecules, 2023
The secondary metabolites of clerodane diterpenoids have been found in several plant species from various families and in other organisms. In this review, we included articles on clerodanes and neo-clerodanes with cytotoxic or anti-inflammatory activity ...
Rubria Marlen Martínez-Casares, Liliana Hernández-Vázquez, Angelica Mandujano, Leonor Sánchez-Pérez, Salud Pérez-Gutiérrez, Julia Pérez-Ramos   +5 more
doaj   +1 more source

A Review on the Ethnopharmacology and Phytochemistry of the Neotropical Sages (Salvia Subgenus Calosphace; Lamiaceae) Emphasizing Mexican Species

Frontiers in Pharmacology, 2022
Salvia is the most diverse genus within the mint family (Lamiaceae), many of its species are well-known due to their medicinal and culinary uses. Most of the ethnopharmacological and phytochemical studies on Salvia are centred on species from the ...
Nancy Ortiz-Mendoza, Eva Aguirre-Hernández, Itzi Fragoso-Martínez, María Eva González-Trujano, Francisco A. Basurto-Peña, Martha J. Martínez-Gordillo   +5 more
doaj   +1 more source

Activity of Ajuga iva Extracts Against the African Cotton Leafworm Spodoptera littoralis

Insects, 2020
Control of the crop pest African cotton leafworm, Spodoptera littoralis (Boisduval), by chemical insecticides has led to serious resistance problems. Ajuga plants contain phytoecdysteroids (arthropod steroid hormone analogs regulating metamorphosis) and ...
Leena Taha-Salaime, Galina Lebedev, Jackline Abo-Nassar, Sally Marzouk, Moshe Inbar, Murad Ghanim, Radi Aly   +6 more
doaj   +1 more source

Mediterranean Propolis from the Adriatic Sea Islands as a Source of Natural Antioxidants: Comprehensive Chemical Biodiversity Determined by GC-MS, FTIR-ATR, UHPLC-DAD-QqTOF-MS, DPPH and FRAP Assay

Antioxidants, 2020
There is no systematic report about propolis chemical biodiversity from the Adriatic Sea islands affecting its antioxidant capacity. Therefore, the samples from the islands Krk, Rab, Pag, Biševo and Korčula were collected. Comprehensive methods were used
Lidija Svečnjak, Zvonimir Marijanović, Piotr Okińczyc, Piotr Marek Kuś, Igor Jerković   +4 more
doaj   +1 more source

Efficient production of clerodane and ent-kaurane diterpenes through truncated artificial pathways in Escherichia coli

Beilstein Journal of Organic Chemistry, 2022
The clerodane and ent-kaurane diterpenoids are two typical categories of diterpenoid natural products with complicated polycyclic carbon skeletons and significant pharmacological activities. Despite exciting advances in organic chemistry, access to these
Fang-Ru Li, Xiaoxu Lin, Qian Yang, Ning-Hua Tan, Liao-Bin Dong   +4 more
doaj   +1 more source

A “Green” Homogenate Extraction Coupled with UHPLC-MS for the Rapid Determination of Diterpenoids in Croton Crassifolius

Molecules, 2019
Clerodane diterpenoids are the main bioactive constituents of Croton crassifolius and are proved to have multiple biological activities. However, quality control (QC) research on the constituents are rare.
Jin-Long Tian, Chi Shu, Ye Zhang, Hui-Jun Cui, Xu Xie, Xu-Long Ran, Tian-Shun Chen, Zhi-Huan Zang, Jian-Guo Liu, Bin Li   +9 more
doaj   +1 more source