Results 41 to 50 of about 2,528 (212)

Inhibitors of HIV-1 integrase from Dioscorea bulbifera [PDF]

Songklanakarin Journal of Science and Technology (SJST), 2016
A search for HIV-1 integrase (IN) inhibitors from natural sources has led to the isolation of compounds from Dioscorea bulbifera bulbils. From the bioassay-guided isolation, the chloroform fraction was then fractionated to obtain one new clerodane ...
Prapaporn Chaniad, Chatchai Wattanapiromsakul, Somsak Pianwanit, Supinya Tewtrakul   +3 more
doaj  

Nanoencapsulation of Essential Oils: A Review of Current Trends and Advances in Preparation, Characterization, and Biomedical Applications

Nano Select, Volume 7, Issue 6, June 2026.
This review highlights nanoencapsulation as a powerful strategy to improve the stability, solubility, and bioavailability of essential oils. It surveys key EO‐producing plant families, major bioactive constituents, and therapeutic properties, alongside high‐ and low‐energy nanoformulation methods. Applications across pharmaceutical, cosmetic, food, and
Mateusz Guz, Awatif Belkhiri‐Baines, Krzysztof Szczepanowicz, Anna Trybala   +3 more
wiley   +1 more source

Synthesis of Ent-16-hydroxycleroda-4(18),13-dien-15,16-olide and Ent-cleroda-4(18),13-dien-15,16-olide from (+)-hardwickiic acid

Journal of the Brazilian Chemical Society, 2006
The absolute configurations of two natural diterpene butenolides were confirmed through the synthesis of ent-16-hydroxycleroda-4(18),13-dien-15,16-olide (2) and ent-cleroda-4(18),13-dien-15,16-olide (3), enantiomers of the natural products, starting from
Ide Regina M., Costa Marta, Imamura Paulo M.   +2 more
doaj  

-Clerodane Diterpenoids from

Natural Product Communications, 2014
Four neo -clerodane diterpenoids, neoajugapyrin A, scutegalerins A and B and scutecolumnin C have been isolated from the acetone extract of the aerial parts of Scutellaria galericulata .
Petko I. Bozov, Plamen N. Penchev, Josep Coll   +2 more
doaj   +1 more source

Total synthesis of 1,2,11,12E-tetradehydrohardwickiic acid

Tetrahedron Chem
Clerodane diterpenoids are a large class of natural products found in various species and exhibit a wide range of biological activities. trans-Clerodanes, which feature a trans-decalin core structure, are the most common subfamily of clerodane ...
Wenming Zhu, Duo Zhang, Yucheng Li, Ming Yang   +3 more
doaj   +1 more source

Antiproliferative Diterpenes from a sp. from the Madagascar dry forest [1]

Natural Product Communications, 2015
An ethanol extract of leaves of the plant species Malleastrum sp. collected in northern Madagascar afforded the new clerodane diterpene 18-oxo-cleroda-3,13-dien-16,15-olide ( 1 ), together with the three known clerodane diterpenes 16,18 ...
Yixi Liu, C. Houston Wiedle, Peggy J. Brodie, Martin W. Callmander, R. Rakotondrajaona, Etienne Rakotobe, Vincent E. Rasamison, David G. I. Kingston   +7 more
doaj   +1 more source

Chemical Constituents and Biological Potentials of Teucrium scordium subsp. scordioides Extracts: In Vitro Experimental and In Silico Perspectives

ChemistryOpen, Volume 15, Issue 5, May 2026.
T. scordium subsp. scordioides may represent a natural source of antioxidants and enzyme inhibitors for use in different health‐promoting formulations. This study was undertaken to examine, for the first time, the antioxidant and enzyme inhibitory properties of several extracts obtained from the aerial parts of Teucrium scordium subsp.
Bengusu Hacer Akgul, Sakina Yagi, Mehmet Veysi Cetiz, Enver Saka, Gokhan Zengin, Eulogio J. Llorent‐Martínez, Marina Gómez‐Torres, Ismail Yapıcı, Ilhami Gulcin, Evren Yıldıztugay   +9 more
wiley   +1 more source

H and C NMR Analysis of the -Clerodane Diterpenoid Scutecyprin

Natural Product Communications, 2014
The 1 H and 13 C NMR spectra of the neo -clerodane diterpenoid scutecyprin were completely assigned by using a combination of 2D NMR experiments, which included 1 H- 1 H COSY, HSQC, HMBC and NOESY sequences.
Plamen N. Penchev, Stefka R. Nachkova, Tonka A. Vasileva, Petko I. Bozov   +3 more
doaj   +1 more source

Antinociceptive and anxiolytic-like effects of a neo-clerodane diterpene from Salvia semiatrata aerial parts

Pharmaceutical Biology, 2020
Context Salvia semiatrata Zucc. (Lamiaceae) is a species used as a tranquilizer and to relieve pain in folk medicine in Santiago Huauclilla, Oaxaca, Mexico. Objective To evaluate the antinociceptive and anxiolytic-like effects of S.
Nancy Ortiz-Mendoza, Lizeth M. Zavala-Ocampo, Martha J. Martínez-Gordillo, María Eva González-Trujano, Francisco A. Basurto Peña, Iván J. Bazany-Rodríguez, José Alberto Rivera Chávez, Alejandro Dorazco-González, Eva Aguirre-Hernández   +8 more
doaj   +1 more source

neo-Clerodane diterpenoids from Teucrium alyssifolium

, 1997
Two new rearranged neo-clerodane diterpenoids, alysines D (1) and E (2), were isolated from the aerial parts of Teucrium alyssifolium.
Topcu, G, Eris, C, Ulubelen, A, A. Ulubelen, C. Eriş, G. Topcu   +5 more
core   +1 more source