New halimane and clerodane diterpenoids from Croton cnidophyllus [PDF]
Three new halimane furanoditerpenoids (1–3) and three new clerodane furanoditerpenoids (4–6), along with seven known terpenoids including four pimarane diterpenoids (7–10) and three norisoprenoids (11–13) were isolated from the 95% EtOH extracts of the ...
Xun Wei +5 more
doaj +4 more sources
The drug likeness analysis of anti-inflammatory clerodane diterpenoids [PDF]
Inflammation is an active defense response of the body against external stimuli. Long term low-grade inflammation has been considered as a deteriorated factor for aging, cancer, neurodegeneration and metabolic disorders.
Zheling Feng +3 more
doaj +2 more sources
Phytochemical Screening and Isolation of New Ent-Clerodane Diterpenoids from Croton guatemalensis Lotsy [PDF]
Phytochemical screening of an ethanol–water extract (EWE) from the bark of Croton guatemalensis led to the isolation and identification of eight compounds, among them: five ent-clerodane diterpenoids [junceic acid (1), 6(s)-acetoxy-15,16-diepoxy-ent ...
Sonia Marlen Escandón-Rivera +3 more
doaj +2 more sources
Bioactive Clerodane Diterpenoids from the Leaves of Casearia coriacea Vent [PDF]
Casearia coriacea Vent., an endemic plant from the Mascarene Islands, was investigated following its antiplasmodial potentialities highlighted during a previous screening.
Allison Ledoux +9 more
doaj +2 more sources
Lignans and clerodane diterpenoids from Tinospora sinensis. [PDF]
Four previously undescribed compounds including a tetrahydrofuran lignan ( 1 ), a 7,9′-dinorlignan glucoside ( 2 ), and two clerodane diterpenoid glucosides ( 3–4 ), together with 18 known compounds were isolated ...
Wen C +6 more
europepmc +4 more sources
Grewiifopenes A–K, bioactive clerodane diterpenoids from Casearia grewiifolia Vent. [PDF]
Eleven novel clerodane-type diterpenoids, grewiifopenes A–K (1–4 and 12–18), along with nine known compounds (5–11, 19, and 20) were purified from the dichloromethane extract of the twigs and stems of Casearia grewiifolia Vent. (Salicaceae).
Phanruethai Pailee +10 more
doaj +2 more sources
Clerodane Diterpenoids from Callicarpa hypoleucophylla and Their Anti-Inflammatory Activity [PDF]
Plants of the genus Callicarpa are known to possess several medicinal effects. The constituents of the Taiwan endemic plant Callicarpa hypoleucophylla have never been studied. Therefore, C. hypoleucophylla was selected for our phytochemical investigation.
Yu-Chi Lin +11 more
doaj +2 more sources
Crassifolins Q−W: Clerodane Diterpenoids From Croton crassifolius With Anti-Inflammatory and Anti-Angiogenesis Activities [PDF]
Seven new clerodane diterpenoids, crassifolins Q−W (1–7), along with five known analogues (8–12), were isolated from the roots of Croton crassifolius. Their structures were identified by comprehensive spectroscopic analysis (UV, IR, NMR, and HR-ESI-MS ...
Canjie Li +13 more
doaj +2 more sources
Total Syntheses of Clerodane Diterpenoids—A Review [PDF]
Total syntheses of clerodane diterpenoids have been reviewed from the literature since 2000.
Hisahiro Hagiwara
doaj +2 more sources
Clerodane Diterpenoids from an Edible Plant Justicia insularis: Discovery, Cytotoxicity, and Apoptosis Induction in Human Ovarian Cancer Cells [PDF]
Objectives: The toxicity of chemotherapeutic anticancer drugs is a serious issue in clinics. Drug discovery from edible and medicinal plants represents a promising approach towards finding safer anticancer therapeutics. Justicia insularis T.
Idowu E. Fadayomi +6 more
doaj +2 more sources

