Results 21 to 30 of about 10,001 (185)

Epoxy Clerodane Diterpene Attenuates the Differentiated Adipocyte Hypertrophy and Enhances Mitochondrial Metabolism. [PDF]

ChemistryOpen
Epoxy Clerodane Diterpene (ECD) significantly reduces adipocyte hypertrophy and lipid accumulation in human mesenchymal stem cell (hMSC)‐derived adipocytes. ECD improves mitochondrial membrane potential (ΔΨm), increases thermogenic regulators (UCP‐1, PPARγC1α), decreases adipogenic markers (C/EBPα, PPARγ), and reduces inflammatory mediators (TNF‐α, NF ...
AlSedairy SA, Subash-Babu P, Alhussain MH, Binobead MA, Alshatwi AA.   +4 more
europepmc   +2 more sources

Four Clerodane Diterpenoids From

Natural Product Communications, 2022
A phytochemical component investigation of the bark of Ptychopetalum olacoides led to the isolation of 4 new clerodane-type diterpenoids, namely, ptycholide V ( 1 ), 7α,20-dihydroxykolavelool ( 2 ), ptycholide VI ( 3 ), and ptycholide VII ( 4 ).
Miwa Kubo, Hisaka Tajima, Wanxia Tang, Kenichi Harada, Yoshiyasu Fukuyama   +4 more
doaj   +1 more source

Cytotoxic clerodane diterpenoids from the roots of Casearia barteri Mast. [PDF]

RSC Adv
Tabekoueng GB, Fomo Fozing FA, Mas-Claret E, et al. Cytotoxic clerodane diterpenoids from the roots of Mast. RSC Advances. 2024;14(32):23109-23117.A study of diterpenoids as active ingredients against cancer from the active roots extract of Casearia ...
Tabekoueng GB, Fomo Fozing FA, Mas-Claret E, Langat MK, Frese M, Bissoue AN, Wansi JD, Kamdem Waffo AF, Sewald N, Lenta BN.   +9 more
europepmc   +2 more sources

A “Green” Homogenate Extraction Coupled with UHPLC-MS for the Rapid Determination of Diterpenoids in Croton Crassifolius

Molecules, 2019
Clerodane diterpenoids are the main bioactive constituents of Croton crassifolius and are proved to have multiple biological activities. However, quality control (QC) research on the constituents are rare.
Jin-Long Tian, Chi Shu, Ye Zhang, Hui-Jun Cui, Xu Xie, Xu-Long Ran, Tian-Shun Chen, Zhi-Huan Zang, Jian-Guo Liu, Bin Li   +9 more
doaj   +1 more source

Clerodane Diterpenoids from Croton crassifolius

, 2016
Seven new clerodane diterpenoids (1–7) were isolated from roots of Croton crassifolius, along with six known compounds. The structures were elucidated by extensive spectroscopic methods (IR, UV, HRESIMS, 1D NMR, and 2D NMR), and the structures of 1, 3, 4,
Jiao-Jiao Xu (1835527), Guo-Qiang Li (625328), Xia Wu (203682), Yao-Lan Li (1472815), Wen-Cai Ye (303536), Guo-Cai Wang (625329), Jia-Gui Li (2008684)   +6 more
core   +5 more sources

Efficient production of clerodane and ent-kaurane diterpenes through truncated artificial pathways in Escherichia coli

Beilstein Journal of Organic Chemistry, 2022
The clerodane and ent-kaurane diterpenoids are two typical categories of diterpenoid natural products with complicated polycyclic carbon skeletons and significant pharmacological activities. Despite exciting advances in organic chemistry, access to these
Fang-Ru Li, Xiaoxu Lin, Qian Yang, Ning-Hua Tan, Liao-Bin Dong   +4 more
doaj   +1 more source

Consequences of interspecific plant hybridization on metabolic diversity in naturally occurring hybrid swarms. [PDF]

Plant J
Significance Statement Studies on the effect of hybridization on plant chemistry have mainly been conducted with crop plants and artificially created hybrids, and the few studies that have analyzed naturally occurring hybrids have either examined only a small number of plants and/or only a small number of metabolites.
Zafra-Delgado O, Schneider F, Nakamura Y, Reichelt M, Gershenzon J, Hellwig FH, Köllner TG.   +6 more
europepmc   +2 more sources

Design and engineering of artificial biosynthetic pathways—where do we stand and where do we go?

FEBS Letters, Volume 597, Issue 23, Page 2897-2907, December 2023., 2023
Microbial production of commodity and specialty chemicals has the potential to decrease our reliance on fossil fuels and reduce the accompanying environmental effects. The scope of traditional biomanufacturing can be greatly enhanced by constructing new‐to‐nature pathways toward target chemicals.
Nika Sokolova, Bo Peng, Kristina Haslinger   +2 more
wiley   +1 more source

Cytotoxicity of clerodane diterpenoids from fresh ripe fruits of Casearia grewiifolia [PDF]

Songklanakarin Journal of Science and Technology (SJST), 2017
A new clerodane diterpene, Caseargrewiin M (1), and one known compound (2) were isolated from fresh ripe fruits of Casearia grewiifolia. The structures of all isolated compounds were evaluated on the basic 1D (1H and 13C) and 2D NMR (COSY, HSQC, HMBC ...
Thanesuan Nuanyai, Benjamat Chailap, Anumart Buakeaw, Songchan Puthong   +3 more
doaj   +1 more source

neo-Clerodane diterpenoids from Scutellaria galericulata [PDF]

China Journal of Chinese Materia Medica, 2016
By means of preparative HPTLC and column chromatography over silica gel and Sephadex LH-20, fourteen diterpenoids were isolated and purified from the whole plants of Scutellaria galericulata. Based on the physico-chemical properties and spectral data, their structures were elucidated and identified as：scutebarbatine D(1), scutolide A(2), scutolide K(3),
Kai, Xiao, Lei, Zhang, Qing-Tong, Han, Sheng-Jun, Dai   +3 more
openaire   +2 more sources