Results 41 to 50 of about 10,001 (185)

Inhibitors of HIV-1 integrase from Dioscorea bulbifera [PDF]

Songklanakarin Journal of Science and Technology (SJST), 2016
A search for HIV-1 integrase (IN) inhibitors from natural sources has led to the isolation of compounds from Dioscorea bulbifera bulbils. From the bioassay-guided isolation, the chloroform fraction was then fractionated to obtain one new clerodane ...
Prapaporn Chaniad, Chatchai Wattanapiromsakul, Somsak Pianwanit, Supinya Tewtrakul   +3 more
doaj  

Antifeedant Activity of Neo-clerodane Diterpenoids from Against Colorado Potato Beetle Larvae

Natural Product Communications, 2017
Fourteen neo-clerodane diterpenoids isolated from Scutellaria altissima ( Lamiaceae ) were tested for insect antifeedant activity against Leptinotarsa decemlineata Say.
Petko I. Bozov, Yoana P. Georgieva
doaj   +1 more source

Diterpenoids from Salvia wagneriana

, 2004
From the surface exudate of the aerial parts of Salvia wagneriana, three new clerodane diterpenoids, the known hardwickiic acid and 1,10-didehydrosalviarin, were obtained. Two were bis-diterpenoids.
BISIO, ANGELA, ROMUSSI, GIOVANNI, DETOMMASI N   +2 more
core   +1 more source

Discovery of neo-Clerodane Diterpenoids from Ajuga campylantha as Neuroprotective Agents against Ferroptosis and Neuroinflammation

, 2023
Twelve new neo-clerodane diterpenoids, eight undescribed methoxy/ethoxy acetal analogues, and one new nor-iridane monoterpenoid were isolated from Ajuga campylantha.
Zhikang Zhang (6499571), Huihao Zhou (3135732), Qingyun Tan (6069671), Deyin Wu (1311384), Xing Peng (3874045), Jun Xu (45543), Qiong Gu (562902)   +6 more
core   +3 more sources

Total synthesis of 1,2,11,12E-tetradehydrohardwickiic acid

Tetrahedron Chem
Clerodane diterpenoids are a large class of natural products found in various species and exhibit a wide range of biological activities. trans-Clerodanes, which feature a trans-decalin core structure, are the most common subfamily of clerodane ...
Wenming Zhu, Duo Zhang, Yucheng Li, Ming Yang   +3 more
doaj   +1 more source

Phytochemical Study Conyza Sophiaefolia. Antiinflammatory Activity

Molecules, 2000
From the aerial parts of Conyza sophiaefolia a new alicyclic furan diterpene was isolated and characterized as an E-isomer in C6 of centipedic acid. In addition, the new clerodane type diterpene 12-epi-bacchotricuneatin A as well as two known related ...
O. S. Giordano, A. Juarez, C. E. Tonn, P. C. Rossomando, L. S. Favier, M. J. Simirgiotis   +5 more
doaj   +1 more source

Clerodane Diterpenes from Species: Distribution and a Compilation of their C NMR Spectral Data

Natural Product Communications, 2006
The present work is a review of the literature of clerodane diterpenes from Croton species. It contains a compilation of 13 C NMR data of 83 of these diterpenoids and their biological activities.
Sebastião F. Palmeira Jünior, Lucia M. Conserva, José Maria Barbosa Filho   +2 more
doaj   +1 more source

Pharmacokinetics and Tissue Distribution in Rats After Oral Administration of Tibetan Medicine Wuwei Leze Powder

Chemistry &Biodiversity, Volume 23, Issue 9, September 2026.
Wuwei Leze Powder (WLP), a classic Tibetan medicine for rheumatoid arthritis, is orally administered and undergoes extensive absorption and metabolism in rats. A total of 56 plasma constituents, including 21 prototypes and 35 metabolites, are identified.
Ping Wang, Peng Wang, YiRui Wu, ShuiYing Wu, HuiJuan Xu, WenYu Yang, Ya Tu, Chuan Liu   +7 more
wiley   +1 more source

Four New Clerodane Diterpenoids from Callicarpa pentandra

, 2016
Leaf extracts of Callicarpa pentandra provided four new clerodane-type diterpenoids (1−4), of which 1, 2, and 4 have ring-A-contracted structures. Their structures and stereochemistry were established by spectral data interpretation, and for 3 also by ...
Yuan-Jian Xu (3060102), Leslie J. Harrison (2497495), Swee-Hock Goh (3060096), Jagadese J. Vittal (1493173), Jin Xu (31283)   +4 more
core   +1 more source

Discovery of VEGFR‐2 Inhibitors From Leonurus japonicus via Integrated Genetic Authentication, Molecular Networking, and In Silico Analysis

Archiv der Pharmazie, Volume 359, Issue 8, August 2026.
Genetic authentication of Leonurus japonicus was confirmed using ITS sequencing. UHPLC‐MS/MS‐GNPS analysis and isolation led to a new labdane diterpenoid (1) and known compounds (2–6), with anti‐angiogenic activity validated by EPC assays and VEGFR‐2 docking studies.
Thiyagarajan Raviraj, Chen‐Lin Yu, Aekkhaluck Intharuksa, Shang‐Chih Lai, Vidya Febrasca Tenderly, Yen Chi Loo, Pin‐Wei Chen, Shih‐Wei Wang, Kartiko Arif Purnomo, Soundar Rajan Kulandhaivel, Sedin Renadi, Stephen Lirio, Yuan‐Bin Cheng, Yu‐Liang Yang, Tsong‐Long Hwang, Fang‐Rong Chang, Michal Korinek   +16 more
wiley   +1 more source