Anti-Inflammatory and Cytotoxic Activities of Clerodane-Type Diterpenes [PDF]
Molecules, 2023 The secondary metabolites of clerodane diterpenoids have been found in several plant species from various families and in other organisms. In this review, we included articles on clerodanes and neo-clerodanes with cytotoxic or anti-inflammatory activity ...
Rubria Marlen Martínez-Casares +5 more
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Ent–Clerodane Diterpenoid Inhibitors of Glucose-6-phosphatase from Croton guatemalensis Lotsy [PDF]
PlantsThe Croton genus includes a diverse group of plants with remarkable potential in natural products research, particularly due to their bioactive compounds with hypoglycemic and phytochemical significance.
Sonia Marlen Escandón-Rivera +4 more
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Seasonal and circadian rhythms of clerodane diterpenes and glycosylated flavonoids in two varieties of Casearia sylvestris Sw. (Salicaceae) [PDF]
HeliyonCasearia sylvestris Sw. (Salicaceae) is noted for its morphological and chemical plasticity and pharmacological properties. The present study investigates two of its varieties: C. sylvestris var.
Paula C.P. Bueno +5 more
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Diterpenes with Abietane and Clerodane Skeletons from the Mexican Salvia Species as Potential Bioactive Compounds [PDF]
MoleculesSalvia (Lamiaceae) is Mexico’s most diverse and widely distributed genus. It represents an important natural resource for the country, with approximately 310 species belonging to the subgenera Calosphace, Audibertia, and Heterosphace.
Nancy Ortiz-Mendoza +9 more
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Solidagoic Acids L and M: Novel Antibacterial cis-Clerodane Diterpenoids Isolated from the Inflorescences of Solidago gigantea via a Bioassay-Guided Approach [PDF]
AntibioticsBackground/Objectives: Plant secondary metabolites remain an invaluable source of novel antibacterial phytochemicals in the fight against antibiotic resistance. The medicinal plant Solidago gigantea Ait. (giant goldenrod) is an invasive species in Europe
Márton Baglyas +2 more
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Phytochemical Characterization and Integrated Biological Evaluation of Baccharis dracunculifolia DC Ethanol Extract: Antioxidant, Anti-Inflammatory and Toxicological Evidence [PDF]
PharmaceuticalsBackground/Objectives: Baccharis dracunculifolia DC. is a medicinal plant and the primary botanical source of Brazilian green propolis. This study aimed to characterize the phytochemical profile of its ethanol extract and evaluate its antioxidant, anti ...
Gustavo Ratti da Silva +14 more
doaj +2 more sources
Promising Effects of Casearins in Tumor-Bearing Mice and Antinociceptive Action against Oncologic Pain: Molecular Docking and In Vivo Findings [PDF]
PharmaceuticalsSafer analgesic drugs remain a hard challenge because of cardiovascular and/or gastrointestinal toxicity, mainly. So, this study evaluated in vivo the antiproliferative actions of a fraction with casearins (FC) from Casearia sylvestris leaves against ...
Jurandy do Nascimento Silva +13 more
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Clerodane Diterpenes and Structural Modification of 12-Oxo-Hardwickiic Acid from the Roots of Croton krabas: α‑Glucosidase Inhibitory Activity, Molecular Docking, and ADMET [PDF]
ACS OmegaSunita Uk-at +3 more
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Beilstein Journal of Organic Chemistry, 2022 The clerodane and ent-kaurane diterpenoids are two typical categories of diterpenoid natural products with complicated polycyclic carbon skeletons and significant pharmacological activities. Despite exciting advances in organic chemistry, access to these
Fang-Ru Li +4 more
doaj +1 more source
Molecules, 2022 Extensive research over the past decades has identified numerous phytochemicals that could represent an important source of anti-cancer compounds. There is an immediate need for less toxic and more effective preventive and therapeutic strategies for the ...
Rosaria Acquaviva +5 more
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