Cytotoxic Clerodane Diterpenes from Casearia rupestris
Four new clerodane diterpenes, casearupestrins A-D (1-4), were isolated from the leaves of Casearia rupestris. Compounds 1 and 4 were acetylated to yield 2,7-di-O-acetylcasearupestrin A (5) and 2,6-di-O-acetylcasearupestrin D (6). All compounds were evaluated for cytotoxicity against a small panel of human cancer cell lines.
Vieira-Junior, Gerardo M. +9 more
openaire +4 more sources
Mapping the Technological and Pharmacological Landscape of Casearia sylvestris: An Evidence-Based Prospection for Wound Healing and Pain Management. [PDF]
Technological prospection of Casearia sylvestris for wound healing reveals limited patent and scientific production, concentrated on topical formulations and associated analgesic and anti‐inflammatory properties. Key innovation gaps persist, including insufficient chemical and biological standardization, lack of clinical evidence, and restricted ...
Soutier LG +10 more
europepmc +2 more sources
Eperua oleifera Ducke (Fabaceae) Oilresin Chemical Composition and the Isolation of a Natural Diterpenic Acid Methyl Ester. [PDF]
Eperua oleifera (Fabaceae) oilresin presents not only diterpenic acids, but also diterpenic acid methyl ester. ABSTRACT Eperua oleifera Ducke, commonly known as “copaíba‐jacaré,” produces oilresins traditionally used in folk medicine for wound healing and as antifungal and antibacterial agents, similar to those of Copaifera species.
Ribeiro R +5 more
europepmc +2 more sources
Clerodane diterpenes: sources, structures, and biological activities [PDF]
The clerodane diterpenoids are a widespread class of secondary metabolites and have been found in several hundreds of plant species from various families and in organisms from other taxonomic groups.
Rongtao, Li +2 more
openaire +2 more sources
Diterpene Lactones with Labdane, Halimane and Clerodane Frameworks [PDF]
The labdane, halimane and clerodane type diterpenoids are compounds that have been isolated in plants of several families. These molecules and their derivatives with a lactone group on the side chain or on the decaline system, have a great interest because of their biological properties as insect antifeedant, antiviral, cytotoxic and trypanocidal.
Lúcia, Silva +2 more
openaire +2 more sources
Consequences of interspecific plant hybridization on metabolic diversity in naturally occurring hybrid swarms. [PDF]
Significance Statement Studies on the effect of hybridization on plant chemistry have mainly been conducted with crop plants and artificially created hybrids, and the few studies that have analyzed naturally occurring hybrids have either examined only a small number of plants and/or only a small number of metabolites.
Zafra-Delgado O +6 more
europepmc +2 more sources
Neo-clerodane diterpenes from Ajuga turkestanica [PDF]
The ethyl acetate extract of the aerial parts of Ajuga turkestanica afforded 6 neo-clerodane diterpenes, including two novel compounds, 14, 15-dihydroajugachin B (1) and 14-hydro-15-methoxyajugachin B (2), in addition to the known diterpenoids chamaepitin (3), ajugachin B (4), ajugapitin (5) and lupulin A (6).
Mary H, Grace +3 more
openaire +2 more sources
Clerodane-type Diterpene Glycosides from Dicranopteris pedata [PDF]
AbstractThree new clerodane-type diterpene glycosides, (5R,6S,8R,9S,10R)-6-O-[β-d-glucopyranosyl-(1 → 4)-α-l-rhamnopyranosyl]cleroda-3,13(16),14-diene (1), (5R,6S,8R,9S,10R,13S)-6-O-[β-d-glucopyranosyl-(1 → 4)-α-l-rhamnopyranosyl]-2-ox-oneocleroda-3,13-dien-15-ol (2), (5R,6S,8R,9S,10R)-6-O-[β-d-glucopyranosyl-(1 → 4)-α-l-rhamnopyranosyl]-(13E)-2 ...
Gao, Bei-Bei +6 more
openaire +2 more sources
neo-Clerodane Diterpenes from Salvia herbacea
Chemical investigation of the aerial parts of Salvia herbacea led to the isolation of eight new neo-clerodane diterpenes (1–8), named tehuanins A–H, and three known compounds.
Alfredo Ortega (1575316) +2 more
core +4 more sources
The use of natural antioxidants in meat products has been extensively studied. However, no reports have been found regarding the accumulation of antioxidant residues in meat products over the storage time in cold storage by LC‐DAD‐MS analysis. To manufacture of Punica granatum L.
Elahe Abedi +4 more
wiley +1 more source

