Two New Clerodane Diterpenes from Tinospora sagittata [PDF]
Molecules, 2016 Two new clerodane-type diterpenes, tinosporins C (1) and tinosporins D (2) were isolated from the stems of Tinospora sagittata (Oliv.), together with three known ones, columbin (3), tinophylloloside (4), and tinospinoside D (5).
Fanghao Wan, Wen-Bing Ding, Youzhi Li
exaly +5 more sources
Seasonal and circadian rhythms of clerodane diterpenes and glycosylated flavonoids in two varieties of Casearia sylvestris Sw. (Salicaceae) [PDF]
HeliyonCasearia sylvestris Sw. (Salicaceae) is noted for its morphological and chemical plasticity and pharmacological properties. The present study investigates two of its varieties: C. sylvestris var.
Paula C.P. Bueno +5 more
doaj +3 more sources
Clerodane Diterpenes from the Marine Sponge Raspailia bouryesnaultae Collected in South Brazil [PDF]
Marine Drugs, 2019 The marine sponge Raspailia bouryesnaultae, collected in South Brazil, was selected for detailed investigation considering the results of a screening that pointed to an in vitro antiproliferative effect against non-small cells of human lung cancer (A549)
Cintia Lhullier +7 more
doaj +3 more sources
Three New Clerodane Diterpenes from Polyalthia longifolia var. pendula [PDF]
Molecules, 2014 Three new clerodane diterpenes, (4→2)-abeo-cleroda-2,13E-dien-2,14-dioic acid (1), (4→2)-abeo-2,13-diformyl-cleroda-2,13E-dien-14-oic acid (2), and 16(R&S)- methoxycleroda-4(18),13-dien-15,16-olide (3), were isolated from the unripe fruit of ...
Tung-Ho Wu +11 more
doaj +3 more sources
Advances on Natural Abietane, Labdane and Clerodane Diterpenes as Anti-Cancer Agents: Sources and Mechanisms of Action [PDF]
Molecules, 2022 Extensive research over the past decades has identified numerous phytochemicals that could represent an important source of anti-cancer compounds. There is an immediate need for less toxic and more effective preventive and therapeutic strategies for the ...
Rosaria Acquaviva +5 more
doaj +2 more sources
Potential anti-hepatocellular carcinoma properties and mechanisms of action of clerodane diterpenes isolated from Polyalthia longifolia seeds [PDF]
Scientific Reports, 2022 Diterpenes are secondary metabolites that have attracted much attention due to their potential biological activities including anti-cancer potential. The aim of the current study is to assess the anticancer potential of the six known clerodane diterpenes
Vinay Bharadwaj Tatipamula +7 more
doaj +2 more sources
Flavonoids and Acid-Hydrolysis derivatives of Neo-Clerodane diterpenes from Teucrium flavum subsp. glaucum as inhibitors of the HIV-1 reverse transcriptase–associated RNase H function [PDF]
Journal of Enzyme Inhibition and Medicinal Chemistry, 2021 Bioassay-guided fractionation of the ethyl acetate extract from Teucrium flavum subsp. glaucum, endowed with inhibitory activity towards the HIV-1 reverse transcriptase–associated RNase H function, led to the isolation of salvigenin (1), cirsimaritin (2)
Benedetta Fois +8 more
doaj +2 more sources
Ent–Clerodane Diterpenoid Inhibitors of Glucose-6-phosphatase from Croton guatemalensis Lotsy [PDF]
PlantsThe Croton genus includes a diverse group of plants with remarkable potential in natural products research, particularly due to their bioactive compounds with hypoglycemic and phytochemical significance.
Sonia Marlen Escandón-Rivera +4 more
doaj +2 more sources
Ent-Clerodane Diterpenes from the Bark of Croton oligandrus Pierre ex Hutch. and Assessment of Their Cytotoxicity against Human Cancer Cell Lines [PDF]
Molecules, 2018 New clerodane diterpenes, 12-epi-megalocarpodolide D (2) and an epimeric mixture of crotonolins A (3) and B (4), were isolated from the bark of Croton oligandrus following a bioassay-guided isolation protocol. Known compounds, megalocarpodolide D (1), 12-
Stephanie Tamdem Guetchueng +5 more
doaj +2 more sources
Diterpenes with Abietane and Clerodane Skeletons from the Mexican Salvia Species as Potential Bioactive Compounds [PDF]
MoleculesSalvia (Lamiaceae) is Mexico’s most diverse and widely distributed genus. It represents an important natural resource for the country, with approximately 310 species belonging to the subgenera Calosphace, Audibertia, and Heterosphace.
Nancy Ortiz-Mendoza +9 more
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