Anti-Inflammatory and Cytotoxic Activities of Clerodane-Type Diterpenes
The secondary metabolites of clerodane diterpenoids have been found in several plant species from various families and in other organisms. In this review, we included articles on clerodanes and neo-clerodanes with cytotoxic or anti-inflammatory activity ...
Rubria Marlen Martínez-Casares +5 more
doaj +2 more sources
Clerodane diterpenes from leaves of Casearia sylvestris Swartz [PDF]
Ethanolic extracts of the leaves of Casearia sylvestris yielded a novel clerodane diterpene, 15-hydroxy-3-cleroden-2-one, together with the known diterpenes (-)-hardwickiic acid, reported for the first time from this species, and casearins B and G ...
André G. dos Santos +4 more
doaj +2 more sources
13C-NMR Data of Diterpenes Isolated from Aristolochia Species
The genus Aristolochia,an important source of physiologically active compounds that belong to different chemical classes, is the subject of research in numerous pharmacological and chemical studies.
Antônio Flávio de Carvalho Alcântara +3 more
doaj +2 more sources
Solidagoic Acids L and M: Novel Antibacterial cis-Clerodane Diterpenoids Isolated from the Inflorescences of Solidago gigantea via a Bioassay-Guided Approach [PDF]
Background/Objectives: Plant secondary metabolites remain an invaluable source of novel antibacterial phytochemicals in the fight against antibiotic resistance. The medicinal plant Solidago gigantea Ait. (giant goldenrod) is an invasive species in Europe
Márton Baglyas +2 more
doaj +2 more sources
Epoxy Clerodane Diterpene Attenuates the Differentiated Adipocyte Hypertrophy and Enhances Mitochondrial Metabolism. [PDF]
Epoxy Clerodane Diterpene (ECD) significantly reduces adipocyte hypertrophy and lipid accumulation in human mesenchymal stem cell (hMSC)‐derived adipocytes. ECD improves mitochondrial membrane potential (ΔΨm), increases thermogenic regulators (UCP‐1, PPARγC1α), decreases adipogenic markers (C/EBPα, PPARγ), and reduces inflammatory mediators (TNF‐α, NF ...
AlSedairy SA +4 more
europepmc +2 more sources
Mapping the Technological and Pharmacological Landscape of Casearia sylvestris: An Evidence-Based Prospection for Wound Healing and Pain Management. [PDF]
Technological prospection of Casearia sylvestris for wound healing reveals limited patent and scientific production, concentrated on topical formulations and associated analgesic and anti‐inflammatory properties. Key innovation gaps persist, including insufficient chemical and biological standardization, lack of clinical evidence, and restricted ...
Soutier LG +10 more
europepmc +2 more sources
Clerodane Diterpenes and Structural Modification of 12-Oxo-Hardwickiic Acid from the Roots of Croton krabas: α‑Glucosidase Inhibitory Activity, Molecular Docking, and ADMET [PDF]
Sunita Uk-at +3 more
doaj +2 more sources
The clerodane and ent-kaurane diterpenoids are two typical categories of diterpenoid natural products with complicated polycyclic carbon skeletons and significant pharmacological activities. Despite exciting advances in organic chemistry, access to these
Fang-Ru Li +4 more
doaj +1 more source
neo-Clerodane Diterpenes from Salvia herbacea
Chemical investigation of the aerial parts of Salvia herbacea led to the isolation of eight new neo-clerodane diterpenes (1–8), named tehuanins A–H, and three known compounds.
Alfredo Ortega (1575316) +2 more
core +4 more sources
The use of natural antioxidants in meat products has been extensively studied. However, no reports have been found regarding the accumulation of antioxidant residues in meat products over the storage time in cold storage by LC‐DAD‐MS analysis. To manufacture of Punica granatum L.
Elahe Abedi +4 more
wiley +1 more source

