Results 21 to 30 of about 2,528 (212)
Mapping the Technological and Pharmacological Landscape of Casearia sylvestris: An Evidence-Based Prospection for Wound Healing and Pain Management. [PDF]
Chem BiodiversTechnological prospection of Casearia sylvestris for wound healing reveals limited patent and scientific production, concentrated on topical formulations and associated analgesic and anti‐inflammatory properties. Key innovation gaps persist, including insufficient chemical and biological standardization, lack of clinical evidence, and restricted ...
Soutier LG +10 more
europepmc +2 more sources
Pharmacokinetics and Tissue Distribution in Rats After Oral Administration of Tibetan Medicine Wuwei Leze Powder. [PDF]
Chem BiodiversWuwei Leze Powder (WLP), a classic Tibetan medicine for rheumatoid arthritis, is orally administered and undergoes extensive absorption and metabolism in rats. A total of 56 plasma constituents, including 21 prototypes and 35 metabolites, are identified.
Wang P +7 more
europepmc +2 more sources
Consequences of interspecific plant hybridization on metabolic diversity in naturally occurring hybrid swarms. [PDF]
Plant JSignificance Statement Studies on the effect of hybridization on plant chemistry have mainly been conducted with crop plants and artificially created hybrids, and the few studies that have analyzed naturally occurring hybrids have either examined only a small number of plants and/or only a small number of metabolites.
Zafra-Delgado O +6 more
europepmc +2 more sources
Biomolecules, 2021 Dietary supplements based on Teucrium chamaedrys L. subsp. chamaedrys aerial parts were banned, due to the hepatotoxicity of furan-containing neo-clerodane constituents.
Simona Piccolella +5 more
doaj +1 more source
The drug likeness analysis of anti-inflammatory clerodane diterpenoids
Chinese Medicine, 2020 Inflammation is an active defense response of the body against external stimuli. Long term low-grade inflammation has been considered as a deteriorated factor for aging, cancer, neurodegeneration and metabolic disorders.
Zheling Feng +3 more
doaj +1 more source
Novel Terpenoids from the New Zealand Liverworts and
Natural Product Communications, 2010 Diethylether extracts of New Zealand liverworts Jamesoniella colorata and Bazzania novae-zelandiae were investigated to reveal novel terpenoids. The former extract afforded a new modified clerodane-type diterpenoid, and the latter gave a degraded ...
Masao Toyota +4 more
doaj +1 more source
An Unusual Bisnor-clerodane Diterpenoid from
Natural Product Communications, 2010 The stem bark of Polyalthia simiarum has yielded a new bisnor-type clerodane diterpenoid, 2-oxo-14,15-bisnor-3,11 E -kolavadien-13-one ( 1 ), and three previously known clerodane derivatives, kolavenic acid ( 2 ), 16β-hydroxycleroda-3,13(14) Z -dien-15 ...
Selina Kabir +4 more
doaj +1 more source
Four Clerodane Diterpenoids From
Natural Product Communications, 2022 A phytochemical component investigation of the bark of Ptychopetalum olacoides led to the isolation of 4 new clerodane-type diterpenoids, namely, ptycholide V ( 1 ), 7α,20-dihydroxykolavelool ( 2 ), ptycholide VI ( 3 ), and ptycholide VII ( 4 ).
Miwa Kubo +4 more
doaj +1 more source
Diterpene Lactones with Labdane, Halimane and Clerodane Frameworks
Natural Product Communications, 2011 The labdane, halimane and clerodane type diterpenoids are compounds that have been isolated in plants of several families. These molecules and their derivatives with a lactone group on the side chain or on the decaline system, have a great interest ...
Lúcia Silva +2 more
doaj +1 more source
Journal of Enzyme Inhibition and Medicinal Chemistry, 2021 Bioassay-guided fractionation of the ethyl acetate extract from Teucrium flavum subsp. glaucum, endowed with inhibitory activity towards the HIV-1 reverse transcriptase–associated RNase H function, led to the isolation of salvigenin (1), cirsimaritin (2)
Benedetta Fois +8 more
doaj +1 more source