Results 211 to 220 of about 17,211 (306)

Inflammation Associated With Obesity, Aging, and Amyloid Burden in Adults With Down Syndrome

Obesity, EarlyView.
ABSTRACT Objective Adults with Down syndrome (DS) often show elevated systemic inflammation, but the association with obesity, aging, and Alzheimer's disease (AD) pathology is not well understood. Methods Data were drawn from 188 nondemented adults with DS participating in the Alzheimer Biomarkers Consortium‐DS (ABC‐DS). Participants completed clinical
Victoria L. Fleming‐Batayneh, Brian C. Helsel, Lauren T. Ptomey, Benjamin L. Handen, Mark Mapstone, Melissa Petersen, Sharon J. Krinsky‐McHale, Christy L. Hom, Davneet Minhas, Weiquan Luo, Charles Laymon, Joseph H. Lee, Annie Cohen, Beau M. Ances, Adam M. Brickman, Margaret Pulsifer, H. Diana Rosas, Florencia Lai, Shahid H. Zaman, Elizabeth Head, Dana Tudorascu, Julie Price, Fredrick Schmitt, Bradley T. Christian, Ozioma Okonkwo, Sigan L. Hartley, for the Alzheimer Biomarkers Consortium‐Down Syndrome (ABC‐DS) Investigators, Beau M. Ances, Howard F. Andrews, Karen Bell, Rasmus M. Birn, Adam M. Brickman, Peter Bulova, Jeff Burns, Amrita Cheema, Kewei Chen, Bradley T. Christian, Isabel Clare, Ann D. Cohen, Eric W. Doran, Tatiana M. Foroud, Benjamin L. Handen, Jordan Harp, Sigan L. Hartley, Elizabeth Head, Denise Head, Christy Hom, Lawrence Honig, Milos D. Ikonomovic, Sterling C. Johnson, M. Ilyas Kamboh, David Keator, Julia K. Kofler, William Charles Kreisl, Sharon J. Krinsky‐McHale, Florence Lai, Patrick Lao, Charles Laymon, Joseph Hyungwoo Lee, Ira T. Lott, Victoria Lupson, Mark Mapstone, Davneet Singh Minhas, Neelesh Nadkarni, Sid O'Bryant, Deborah Pang, Melissa Petersen, Julie C. Price, Lauren Ptomey, Margaret Pulsifer, Michael S. Rafii, Herminia Diana Rosas, Frederick Schmitt, Nicole Schupf, Wayne P. Silverman, Dana L. Tudorascu, Rameshwari Tumuluru, Badri Varadarajan, Michael A. Yassa, Shahid Zaman, Fan Zhang   +80 more
wiley   +1 more source

Novel Targets for Fruit Conservation Strategies Revealed by Omics Studies: A Systematic Review and Meta-Analysis. [PDF]

Int J Food Sci
Storch TT, Pegoraro C, Quecini V, Rombaldi CV, Girardi CL.   +4 more
europepmc   +1 more source

SURMOUNT‐REAL UK: A Pragmatic Randomized Clinical Trial to Assess the Effectiveness of Tirzepatide in Adults With Obesity

Obesity, EarlyView.
ABSTRACT Objective SURMOUNT‐REAL UK will evaluate the effectiveness of tirzepatide when offered in addition to standard‐of‐care (SoC) in adults with Class I obesity (BMI ≥ 30 and ≤ 34.9 kg/m2) and without diabetes in a UK primary care setting. Methods A 5‐year, phase 4, multicenter, open‐label, pragmatic randomized clinical trial is enabled through ...
Martin K. Rutter, Julie Mount, J. Martin Gibson, Joanne Webb, Cheryl Marler, Catherine Reed, Mugdha Gore, Wenyu Ye, Elisa Gomez Valderas, John Wilding, Naveed Sattar, Melanie J. Davies, Kamlesh Khunti, Richard Haynes, Rachel L. Batterham   +14 more
wiley   +1 more source

Preoperative risk factors and their cumulative impact on nonsatisfaction after benign hysterectomy: A population-based nation-wide register study. [PDF]

Acta Obstet Gynecol Scand
Makdessi Björkström L, Fredrikson M, Borendal Wodlin N, Nilsson L, Borgfeldt C, Kjølhede P.   +5 more
europepmc   +1 more source

Impact of Life‐Context Factors on Chronic Rhinosinusitis 22‐Item Sinonasal Outcomes Test: Systematic Review + Meta‐Analysis

Otolaryngology–Head and Neck Surgery, EarlyView.
Abstract Objective Chronic rhinosinusitis (CRS) affects all sociodemographic groups. While studies have explored social determinants of health (SDOH), sociodemographics, and health behaviors, their specific effects on CRS outcomes are unclear, making tailored care difficult.
Kassandra M. Jade, George A. Scangas, Victoria S. Lee, Li‐Xing Man, Edward D. McCoul, Gabriela Guevara, Anahita Nourmahnad, John M. Reynolds, Corinna G. Levine   +8 more
wiley   +1 more source

Is hypertension negatively associated with memory performance in women during climacteric? A systematic review. [PDF]

BMC Womens Health
da Silva AP, Fávero LS, Corrêa AB, Bardella MDC, Leite LFPA, da Silva LSL, Júnior MFT, Gonçalves LDS, de Moraes C.   +8 more
europepmc   +1 more source

Alkaline Phosphatases: A Potential Cause of Variability in Therapeutic Response to Continuous Subcutaneous Foslevodopa/Foscarbidopa Infusion?

Movement Disorders, EarlyView.
Manon Auffret, Marc Vérin
wiley   +1 more source

Improvements in interoceptive sensibility, pain and functional clinical outcome measures after participation in an interdisciplinary pain management program

PM&R, EarlyView.
Abstract Background Altered interoception, the sense of signals from inside the body, is linked to chronic pain. No studies to date have examined whether interoceptive sensibility, one's self‐reported beliefs about the body and tendencies to be internally focused, changes following participation in an interdisciplinary pain management program (IPMP ...
Stephanie Voss, Shannon La Penna, Alison Yum, Neha P. Gothe, Christine M. Gagnon   +4 more
wiley   +1 more source

A self-care smartphone application for midlife women with menopausal symptoms: A proof-of-concept study. [PDF]

Digit Health
Ohsuga T, Egawa M, Tsuyuki K, Ohtsuki M, Wanjie Y, Juan S, Hinotani R, Takahashi Y, Nakayama T, Mandai M.   +9 more
europepmc   +1 more source

Endocrine therapy‐induced cancer‐related fatigue in hormone‐dependent malignancies: Mechanisms, impact, and management strategies

Precision Medical Sciences, EarlyView.
Multipathway schematic of endocrine therapy–induced cancer‐related fatigue. Endocrine interventions trigger four interacting mechanisms—neuroendocrine dysregulation, systemic inflammation, energy‐metabolic failure, and psycho‐behavioral amplification—that culminate in the multidimensional CRF phenotype.
Jiajing Jiang, Jun Lu, Sen Qin, Ruzhou Chen, Qiuchen Zhang, Lvqi He, Yubei Li, Jingyao Yan   +7 more
wiley   +1 more source