Results 41 to 50 of about 1,310,553 (296)

Optimized J2 Recovery for Multi‐Decadal Geophysical Studies

open access: yesGeophysical Research Letters
The time history of the Earth's dynamic oblateness, or J2, is a unique climate data record, with its estimation from satellite laser ranging (SLR) tracking data beginning in 1976.
B. D. Loomis   +6 more
doaj   +1 more source

Molecular determinants of signal transduction in tropomyosin receptor kinases

open access: yesFEBS Open Bio, EarlyView.
Tropomyosin receptor kinases control critical neuronal functions, but how do the same receptors produce diverse cellular responses? This review explores the structural mechanisms behind Trk signaling diversity, focusing on allosteric modulation and ligand bias.
Giray Enkavi
wiley   +1 more source

KLK7 overexpression promotes an aggressive phenotype and facilitates peritoneal dissemination in colorectal cancer cells

open access: yesFEBS Open Bio, EarlyView.
KLK7, a tissue kallikrein‐related peptidase, is elevated in advanced colorectal cancer and associated with shorter survival. High KLK7 levels in ascites correlate with peritoneal metastasis. In mice, KLK7 overexpression increases metastasis. In vitro, KLK7 enhances cancer cell proliferation, migration, adhesion, and spheroid formation, driving ...
Yosr Z. Haffani   +6 more
wiley   +1 more source

Understanding bio‐based polymers: A study of origins, properties, biodegradation and their impact on health and the environment

open access: yesFEBS Open Bio, EarlyView.
This review provides an overview of bio‐based polymer sources, their unique functional properties and their environmental impact, and addresses their role as sustainable alternatives. It discusses end‐of‐life options, including composting and anaerobic digestion for renewable energy.
Sabina Kolbl Repinc   +8 more
wiley   +1 more source

Tracking Motor Progression and Device‐Aided Therapy Eligibility in Parkinson's Disease

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To characterise the progression of motor symptoms and identify eligibility for device‐aided therapies in Parkinson's disease, using both the 5‐2‐1 criteria and a refined clinical definition, while examining differences across genetic subgroups.
David Ledingham   +7 more
wiley   +1 more source

Water Vapor Spectroscopy and Thermodynamics Constrain Earth's Tropopause Temperature

open access: yesAGU Advances
As Earth warms, the tropopause is expected to rise, but predictions of its temperature change are less certain. Longstanding theories employing “gray” radiation tie the tropopause temperature to outgoing longwave radiation (OLR), but this is in contrast ...
Brett A. McKim   +3 more
doaj   +1 more source

Ajuste dos simuladores de dados meteorológicos do modelo EPIC para diferentes locais do Estado de São Paulo Adjustment of the simulators of meteorological data of the EPIC model for different localities in the State of São Paulo, Brazil

open access: yesRevista Brasileira de Engenharia Agrícola e Ambiental, 2005
O modelo EPIC (Erosion Productivity Impact Calculator) foi desenvolvido para simular o efeito de estratégias de manejos agrícolas em recursos hídricos e produtividade de solos.
Angélica G. Picini   +3 more
doaj   +1 more source

The Impact of Tilburg Frailty on Poststroke Fatigue in First‐Ever Stroke Patients: A Cross‐Sectional Study With Unified Measurement Tools and Improved Statistics

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Poststroke fatigue (PSF) and frailty share substantial overlap in their manifestations, yet previous research has yielded conflicting results due to the use of heterogeneous frailty assessment tools. Objective To evaluate the independent impact of frailty on PSF using a unified measurement system (Tilburg Frailty Indicator, TFI ...
Chuan‐Bang Chen   +6 more
wiley   +1 more source

Network Localization of Fatigue in Multiple Sclerosis

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Fatigue is among the most common symptoms and one of the main factors determining the quality of life in multiple sclerosis (MS). However, the neurobiological mechanisms underlying fatigue are not fully understood. Here we studied lesion locations and their connections in individuals with MS, aiming to identify brain networks ...
Olli Likitalo   +12 more
wiley   +1 more source

Groundwater storage variability in West Africa using gravity recovery and climate experiment (GRACE) and global land data assimilation system (GLDAS) data

open access: yesEQA
The study integrates Gravity Recovery and climate Experiment (GRACE) satellite data which provides Terrestrial Water Storage with Global Land Data Assimilation System (GLDAS) which provide the hydrological components of surface water and soil moisture ...
Muhammad Magaji Ibrahim   +2 more
doaj   +1 more source

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