Results 201 to 210 of about 879,580 (295)

Whole Genome Resequencing Reveals the Genetic Basis of Desert Arid Climate Adaptation in Lop Sheep. [PDF]

Animals (Basel)
Yang C, Gong C, Khamili A, Li X, Gao Q, Chen H, Xiang X, Wang J, Han C, Gao Q.   +9 more
europepmc   +1 more source

MicroRNA‐375‐3p Targets Fatty Acid Synthase and Relish to Regulate Energy Allocation During Pupal Metamorphosis and Starvation

Advanced Science, EarlyView.
During pupal metamorphosis and starvation, elevated 20‐hydroxyecdysone (20E) and suppressed insulin trigger Forkhead box O (FOXO) nuclear translocation, enhancing miR‐375‐3p expression. This downregulates fatty acid synthase (FASN) and Relish, promoting lipid breakdown for energy while prioritizing antioxidant responses over immune functions to support
Peng Chen, Meiqi Cheng, Jianhui Wang, Jing Tang, Xiaoqiao Huang, Yusi Li, Huiling Zhou, Ling Zhang, Yi Dong, Chengjun Li, Bin Li   +10 more
wiley   +1 more source

Haploblocks contribute to parallel climate adaptation following global invasion of a cosmopolitan plant. [PDF]

Nat Ecol Evol
Battlay P, Hendrickson BT, Mendez-Reneau JI, Santangelo JS, Albano LJ, Wilson J, Caizergues AE, King N, Puentes A, Tudoran A, Violle C, Vasseur F, Patterson CM, Foster M, Stamps C, Innes SG, Allio R, Angeoletto F, Anstett DN, Anstett J, Bucharova A, Comerford MS, David S, Falahati-Anbaran M, Godsoe W, González-Lagos C, Gundel PE, Hood GR, Lampei C, Lara C, Lázaro-Lobo A, Silva Leandro D, Merritt TJS, Mitchell N, Mohammadi Bazargani M, Moles A, Murúa M, Paule J, Pfeiffer V, Raeymaekers JAM, Rennison DJ, Rios RS, Rowntree JK, Schneider AC, Stack Whitney K, Tamburrino Í, VanWallendael A, Kim PY, Ness RW, Johnson MTJ, Hodgins KA, Kooyers NJ.   +51 more
europepmc   +1 more source

Fermented Lacticaseibacillus Paracasei Cultures Ameliorate Colitis by Modulating Microbiota‐Derived Tryptophan Metabolism and Macrophage Polarization

Advanced Science, EarlyView.
A solid‐state fermented probiotic (PYW) is developed using wheat bran as substrate, containing high viable Lacticaseibacillus paracasei and bioactive metabolites. PYW alleviates intestinal inflammation by gut microbiota composition, enriching indole derivatives, activating aryl hydrocarbon receptor signaling, and regulating macrophage polarization. PYW
Heng Zhang, Jingzhou Sun, Xin Zheng, Huiqing Yang, Aowen Xie, Yuxuan Ding, Yuxia Mei, Jinshan Li, Yuanliang Hu, Min Ren, Yangyang Liu, Yunxiang Liang   +11 more
wiley   +1 more source

Thermal Vulnerability and Potential Cultivation Areas of Four Day-Neutral Strawberries in Chile: Implications for Climate Adaptation. [PDF]

Plants (Basel)
Sierra-Almeida A, Morales LV, Guerrero D, Hasbún RJN, Retamal L, Garrido-Bigotes A, Tamburrino Í, Maruri A.   +7 more
europepmc   +1 more source

Light Therapy Alleviates Addiction‐Related Symptoms and Reshapes Habenula and Midbrain Pathways

Advanced Science, EarlyView.
This study investigates light therapy for treating Internet Gaming Disorder (IGD). Functional MRI (fMRI) data reveal that light therapy enhances brain connectivity, particularly between the habenula and the medial orbitofrontal cortex (mOFC). These changes are associated with reduced withdrawal symptoms and addiction severity, highlighting the ...
Jinhui Li, Huiyang Huang, Cunhao Hu, Xuan Zhang, Song Lin, Xiaodan Huang, Ti‐fei Yuan, Kwok‐Fai So, Lu Huang, Chaoran Ren, Qian Tao   +10 more
wiley   +1 more source

Narratives of climate adaptation and linkages to psychosocial and nutritional health in a Zimbabwean rural community. [PDF]

World Dev Sustain
Bhatasara S, Nwosu C, Macheka L, Nyamwanza AM.   +3 more
europepmc   +1 more source

An Advanced High‐Performance Ultrafast Ammonium‐Ion Aqueous Battery Based on Dual‐Metal Redox Open Framework Molecular Magnet

Advanced Science, EarlyView.
The Prussian Blue Analogue molecular magnet KMnFeHCF is demonstrated as a high‐performance cathode for ultra‐fast aqueous ammonium‐ion batteries. A full cell using KMnFeHCF and graphite delivers ~71 mAh g−1 at 1.25 A g−1 and ~51 mAh g−1 at 2.2 A g−1, retaining 50% capacity after 1850 cycles. Its scalability, cycling stability, and low cost offer strong
Nilasha Maiti, Pramod Bhatt, Manoj K Sharma, Sher Singh Meena, Mayuresh D Mukadam, Soumen Samanta   +5 more
wiley   +1 more source

Temperature-Photoperiod Interaction in Rice Phenology for Climate Adaptation: Insights Into Glycerate-Associated Metabolic Responses. [PDF]

Physiol Plant
Lee HS, Kim JH, Jo SH, Yang SY, Baek JK, Song YS, Shon JY, Chung NJ.   +7 more
europepmc   +1 more source

Targeting Microglial CD49a Inhibits Neuroinflammation and Demonstrates Therapeutic Potential for Parkinson's Disease

Advanced Science, EarlyView.
This study shows that integrin receptor CD49a (Itga1 gene) is significantly upregulated in hyperactivated microglia and microglia‐specific knockdown of Itga1 rescues neuroinflammation and neurodegeneration in a chronic Parkinson's disease (PD) model by targeting PGAM5‐mediated mitochondrial dysfunction and NLRP3 activation. Targeted inhibition of CD49a
Huanpeng Lu, Yunmin Zhu, Xi Wang, Zelin Wu, Zijian Xu, Rongqing Chen, Yanwu Guo   +6 more
wiley   +1 more source