Results 151 to 160 of about 5,789,121 (307)

THE WEAKEST LINK HYPOTHESIS FOR ADAPTIVE CAPACITY: AN EMPIRICAL TEST [PDF]

open access: yes
Yohe and Tol (2001) built an indexing method for vulnerability based on the hypothesis that the adaptive capacity for any system facing a vector of external stresses could be explained by the weakest of eight underlying determinants – the so-called ...
Richard S.J. Tol, Gary W. Yohe
core   +2 more sources

GSTM4 Suppresses Prostate Cancer Progression by Targeting TRIM27‐mediated ACLY Ubiquitination and Lipid Metabolism

open access: yesAdvanced Science, EarlyView.
GSTM4 enhances the interaction between ACLY and the E3 ubiquitin ligase TRIM27, thereby increasing K48‐linked ubiquitination at the K554 site of ACLY and promoting its degradation. Consequently, GSTM4 regulates lipid synthesis, as well as the proliferation and metastasis of PCa cells, by modulating ACLY stability.
Kang‐Ping Xiong   +11 more
wiley   +1 more source

Quantum‐Trained AI Enables Inverse Design of Organic Frontier Orbitals at Billion‐Scale

open access: yesAdvanced Science, EarlyView.
Quantum‐trained AI links molecular substructures to frontier‐orbital energetics and enables interpretable screening across nearly one billion GDB‐13 molecules. By combining fragment‐ and ring‐level insights with donor–acceptor energy alignment against ITIC, the framework narrows an immense chemical space to a small set of promising candidates and ...
Yeongnam Ko, Se Jin Kim, Ki Chul Kim
wiley   +1 more source

Climate change and variability, energy and disaster management: produced risks without produced solutions: rethinking the approach [PDF]

open access: yes, 2008
Accelerated climate change and increasing climate variability is the single largest threat to the international goals of sustainable development, the Millennium Development Goals (MDGs) and disaster risk reduction.
O'Brien, Geoff   +3 more
core  

Symbiont‐Induced HSP83 Establishes Two‐Tiered Control of Antifungal Immunity in an Invasive Beetle–Fungus Complex

open access: yesAdvanced Science, EarlyView.
In an invasive beetle–fungus complex, the mutualist Leptographium procerum induces host HSP83 and modulates Toll‐dependent antifungal immunity. HSP83 mediates two‐tiered control by associating with selected fungal recognition receptors and restraining Dorsal‐driven antimicrobial peptide transcription.
Qingtai Yang   +8 more
wiley   +1 more source

Overview on Adaptive Capacity to Climate Change

open access: yesInternational Journal of Current Microbiology and Applied Sciences, 2020
openaire   +1 more source

Adaptive learning in NRM for climate change adaptation

open access: yes, 2014
Regional natural resource management (NRM) bodies across Australia are currently incorporating climate change adaptation information into their regional NRM plans, drawing on information produced from eight research clusters under the NRM Planning for ...
Low Choy, Darryl Charles   +2 more
core  

Constrained Forest Methane Sink by Thermal Adaptation of Soil Methanotrophs

open access: yesAdvanced Science, EarlyView.
Climate warming can stimulate methanotroph‐mediated CH4 oxidation in forest soils, thereby mitigating the increase in atmospheric CH4 concentrations. By integrating evidence from a macro‐climatic thermal gradient and a 70‐day incubation experiment, this study demonstrates that microbial methanotrophs can adapt to long‐term temperature changes at the ...
Baizhi Jiang   +5 more
wiley   +1 more source

Food security, risk management and climate change [PDF]

open access: yes, 2012
This report identifies major constraints to the adaptive capacity of food organisations operating in Australia. This report is about food security, climate change and risk management.
Rachel Crossley, David Michael
core  

Oral Nanomicelle‐Mediated Sequential Butyrate Production in the Intestine for Ulcerative Colitis and Immunosuppression Treatment

open access: yesAdvanced Science, EarlyView.
After oral administration, inodorous GLU‐BA self‐assembles into nanomicelles in aqueous environments to resist premature gastric adsorption. Upon reaching the intestine, endogenous esterases rapidly cleave the built‐in ester bonds in these nanomicelles to release BA and GLU, with GLU further metabolized by gut microbiota to gradually generate BA ...
Feifei Xin   +9 more
wiley   +1 more source

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