STING/Type I Interferon Pathway Activation Confers Multimodal Therapeutic Benefits in Osteomyelitis
STING/type I interferon signaling counteracts osteomyelitis through coordinated control of pain, bone destruction, and abscess formation. It inhibits pathogen‐induced nociceptor activation, restrains osteoclast‐mediated bone resorption, and suppresses IL‐1β‐driven neutrophil recruitment.
Yang Chen +19 more
wiley +1 more source
Seawater Electrolysis Enables Multipathway Climate Change Mitigation through Atmospheric Carbon Dioxide Removal, Renewable Hydrogen Production, and Cement and Concrete Decarbonization. [PDF]
Chen X +20 more
europepmc +1 more source
Human water demand constrains China's feasible afforestation potential more strongly than is commonly recognized, and future climate change further intensifies this limitation. Integrating land‐use optimization with water‐saving measures substantially expands feasible afforestation area and associated carbon sinks, revealing a practical pathway to ...
Binbin Huang +5 more
wiley +1 more source
Allometric equations for orchard and vineyard trees: enhancing AFOLU-based climate change mitigation. [PDF]
Kwak M +5 more
europepmc +1 more source
Hippocampal CA2 perineuronal nets ensheathing excitatory pyramidal neurons are selectively vulnerable to repeated neonatal sevoflurane exposure. Epigenetic upregulation of MMP9 via reduced H3K27me3 disrupts PNN integrity, impairs BDNF–TrkB signaling, and causes synaptic protein loss and dendritic spine deficits, leading to persistent social and spatial
Lirong Liang +11 more
wiley +1 more source
Overcoming heuristics that hinder people's acceptance of climate-change-mitigation technologies. [PDF]
Blöbaum A +5 more
europepmc +1 more source
Huntingtin Aggregate‐Responsive Autophagy Gene Circuit Mitigates Disease Pathology in R6/2 Mice
CD98‐mediated receptor‐mediated transcytosis enables LIP‐CD98 nanocarriers to cross the blood–brain barrier and deliver ARAA to neurons. mHTT aggregates activate the 11G–NarX sensor, initiating Auto‐P and Trans‐P signaling through the VP48–NarL relay.
Jie Zhu +8 more
wiley +1 more source
Enhanced weathering of lizardite-rich sand in seawater: effects of pH and CO<sub>₂</sub> pressure on carbonate formation for climate change mitigation. [PDF]
Ali A +5 more
europepmc +1 more source
Rhizodeposition Drives One Third of Belowground Carbon Input in Agroecosystems
This study quantifies photosynthesized C allocation in the plant–soil system across six crop types: barley, wheat, maize, rice, legumes and grasses. It reports C partitioning into shoot respiration, shoot‐C, root‐C, net rhizodeposition and root‐derived CO2, providing standardized percentage averages and GPP‐derived absolute values as a robust baseline ...
Zhengjun Yan +10 more
wiley +1 more source

