Results 141 to 150 of about 369,950 (266)

Paternal Circadian Disruption Impairs Offspring Cognition via Sperm microRNAs

open access: yesAdvanced Science, EarlyView.
Paternal circadian disruption remodels the sperm small RNA payload, elevating miR‐92a‐3p/miR‐25‐3p levels and perturbing early embryonic gene regulatory programs. Microinjection experiments and single‐embryo transcriptomics reveal sex‐specific developmental vulnerabilities, ultimately impairing offspring hippocampal synaptic plasticity and cognition ...
Kexin Zou   +22 more
wiley   +1 more source

Dynamical-generative downscaling of climate model ensembles. [PDF]

open access: yesProc Natl Acad Sci U S A
Lopez-Gomez I   +5 more
europepmc   +1 more source

Significant impact of forcing uncertainty in a large ensemble of climate model simulations. [PDF]

open access: yesProc Natl Acad Sci U S A, 2021
Fyfe JC   +4 more
europepmc   +1 more source

Climate Modeling [PDF]

open access: yesPAGES news, 2003
Michel Crucifix, Paul Valdes
openaire   +1 more source

Adipocyte‐Derived Leptolin Enhances Energy Expenditure and Prevents Obesity

open access: yesAdvanced Science, EarlyView.
We identified a novel adipokine, which we named leptolin. In humans, leptolin levels in white adipose tissue were positively correlated with exercise and negatively associated with body mass index. We observed elevated leptolin in serum from athletes and lower leptolin in serum from obese individuals.
Jiarui Liu   +17 more
wiley   +1 more source

Climate Observations, Climate Modeling, and Climate Services

open access: yesBulletin of the American Meteorological Society, 2017
Chris Hewitt   +5 more
openaire   +1 more source

Fibronectin1‐Expressing Subicular Circuits Selectively Govern the Retrieval of Novel Object Recognition

open access: yesAdvanced Science, EarlyView.
Fibronectin 1 (FN1)‐expressing subicular subpopulations encode novel object preference and selectively govern retrieval of novel object recognition (NOR) via affecting excitability of entorhinal‐projecting circuit through large conductance Ca2+‐activated potassium (BK) channel. ABSTRACT Novel object recognition (NOR), referring to the cognitive ability
Fan Fei   +15 more
wiley   +1 more source

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