Paternal Circadian Disruption Impairs Offspring Cognition via Sperm microRNAs
Paternal circadian disruption remodels the sperm small RNA payload, elevating miR‐92a‐3p/miR‐25‐3p levels and perturbing early embryonic gene regulatory programs. Microinjection experiments and single‐embryo transcriptomics reveal sex‐specific developmental vulnerabilities, ultimately impairing offspring hippocampal synaptic plasticity and cognition ...
Kexin Zou +22 more
wiley +1 more source
Dynamical-generative downscaling of climate model ensembles. [PDF]
Lopez-Gomez I +5 more
europepmc +1 more source
Significant impact of forcing uncertainty in a large ensemble of climate model simulations. [PDF]
Fyfe JC +4 more
europepmc +1 more source
Adipocyte‐Derived Leptolin Enhances Energy Expenditure and Prevents Obesity
We identified a novel adipokine, which we named leptolin. In humans, leptolin levels in white adipose tissue were positively correlated with exercise and negatively associated with body mass index. We observed elevated leptolin in serum from athletes and lower leptolin in serum from obese individuals.
Jiarui Liu +17 more
wiley +1 more source
Advancing global sea ice prediction capabilities using a fully coupled climate model with integrated machine learning. [PDF]
Gregory W +6 more
europepmc +1 more source
Publisher Correction: Assessing the impact of suppressing Southern Ocean SST variability in a coupled climate model. [PDF]
Purich A +3 more
europepmc +1 more source
Climate Observations, Climate Modeling, and Climate Services
Chris Hewitt +5 more
openaire +1 more source
Fibronectin 1 (FN1)‐expressing subicular subpopulations encode novel object preference and selectively govern retrieval of novel object recognition (NOR) via affecting excitability of entorhinal‐projecting circuit through large conductance Ca2+‐activated potassium (BK) channel. ABSTRACT Novel object recognition (NOR), referring to the cognitive ability
Fan Fei +15 more
wiley +1 more source
Impacts of Climate Change on Grain Production in China, Japan, and South Korea Based on an Improved Economy-Climate Model. [PDF]
Jin H, Chou J, Wang Y, Pei H, Xu Y.
europepmc +1 more source

