Results 131 to 140 of about 369,950 (266)

High Humidity Exacerbates Psoriasiform Skin Disease Relapse by Increasing Tissue‐Resident Memory T Cells via Altering Skin Microbiota

Advanced Science, EarlyView.
We demonstrated that high humidity worsened psoriasis relapse in murine psoriasiform skin inflammation by increasing skin‐resident memory CD8+ cells via upregulating IL‐15Rα on keratinocytes. The increases in IL‐15Rα and memory CD8+ cells were attributed to S. nepalensis and its metabolite ADMA in skin exposed to high humidity.
Chun‐Ling Liang, Yuchao Chen, Chuanjian Lu, Huazhen Liu, Fenglian Qin, Sisi Dai, Feifei Qiu, Haiming Chen, Weihui Lu, Jonathan S. Bromberg, Zhenhua Dai   +10 more
wiley   +1 more source

Improvement of the regional climate model with soil moisture initialization on simulations of Indian summer monsoon. [PDF]

Sci Rep
Karadan MM, Raju PVS.
europepmc   +1 more source

Malectin Alleviates Endoplasmic Reticulum Stress in Gestational Diabetes Mellitus via Glycoprotein Quality Control Mechanisms

Advanced Science, EarlyView.
Malectin alleviates high glucose‐induced ER stress and damage in placental trophoblasts, a function dependent on its six critical carbohydrate‐binding residues. In a GDM mouse model, administration of TAT‐Malectin ameliorated hyperglycemia and placental ER stress and prevented fetal macrosomia.
Jiahui Zhu, Yumeng Zhang, Ye Wang, Xiaoyu Zhu, Ailin Yuan, Weijing Yin, Huangmin Yu, Xuemin Pang, Yufeng He, Yuchen Wang, Tong Wang, Yong Li, Yunlong Si   +12 more
wiley   +1 more source

On solving coordinate problems in climate model output and other geospatial datasets. [PDF]

Open Res Eur
Cherblanc C, Grejs Petersen JP, Bunt F, Torres-Alavez JA, Mottram R.   +4 more
europepmc   +1 more source

Rainfall-runoff modelling based on global climate model and tropical rainfall measuring mission (GCM -TRMM): A case study in Hulu Terengganu catchment, Malaysia. [PDF]

Heliyon, 2023
Che Wan Zanial WN, Malek MA, Md Reba MN, Zaini N, Ahmed AN, Sherif M, Elshafie A.   +6 more
europepmc   +1 more source

Climate Change Threatens Micronutrient Density of European Winter Wheat

Advanced Science, EarlyView.
Micronutrients are vital for human health. Wheat is a major staple crop and a significant source of minerals and B‐vitamins. The impact of climate change on their content remains largely unknown. We evaluated micronutrient levels in European winter wheat grown under historical and projected climate conditions. Our findings indicate that future climates
Da Cao, Jennifer Michel, Eline Lorer, Markus Weinmann, Jacques Le Gouis, Claire Léon, Sibille Perrochon, David Alvarez, Vincent Leemans, Iñaki Balanzategui Guijarro, Jordi Moya Laraño, Sara Sánchez Moreno, Symanczik Sarah, Waibel Matthias, Hervé Vanderschuren, Cécile Thonar, Pierre Delaplace, Dominique Van Der Straeten   +17 more
wiley   +1 more source

Mesoscale Convective Systems in Northeastern North America: identification and evaluation with the convection-permitting version of the Canadian Regional Climate Model. [PDF]

Clim Dyn
Alpizar M, Di Luca A, Gachon P, Roberge F.   +3 more
europepmc   +1 more source

Assessing the impact of suppressing Southern Ocean SST variability in a coupled climate model. [PDF]

Sci Rep, 2021
Purich A, Boschat G, Liguori G.
europepmc   +1 more source

Electroacupuncture Improves the Learning and Memory by Modulating Hippocampal Glucose Metabolism through IGF1/IGF1R Signaling in Alzheimer's Disease

Advanced Science, EarlyView.
Electroacupuncture (EA) ameliorates learning and memory function in 5×FAD mice by regulating the brain glucose metabolic network. This neuroprotective effect is closely related to enhancing neuronal energy utilization via the IGF1/IGF1R signaling pathway.
Shengxiang Liang, Qingqing Zhang, Xiuxiu Wang, Lixin Peng, Xinru Ji, Jiawei Wang, Yusi Zhang, Jiayang Huang, Junchao Yang, Shiqi Zhan, Yiping Xiao, Weilin Liu, Lidian Chen   +12 more
wiley   +1 more source

Reduced cloud cover errors in a hybrid AI-climate model through equation discovery and automatic tuning. [PDF]

Sci Rep
Grundner A, Beucler T, Savre J, Lauer A, Schlund M, Eyring V.   +5 more
europepmc   +1 more source