Results 51 to 60 of about 25,986,593 (308)

Model consensus projections of US regional hydroclimates under greenhouse warming

open access: yesEnvironmental Research Letters, 2019
We investigate ensemble-mean (‘consensus’) values of resolution-weighted CMIP5 multi-model simulations of 1976–2005 summer regional hydroclimates, and of their projected 2070–2099 changes under three progressively more severe representative concentration
Thomas J Phillips   +2 more
doaj   +1 more source

Greenhouse Gas Forcing and Climate Feedback Signatures Identified in Hyperspectral Infrared Satellite Observations

open access: yesGeophysical Research Letters, 2023
Global greenhouse gas forcing and feedbacks are the primary causes of climate change but have limited direct observations. Here we show that continuous, stable, global, hyperspectral infrared satellite measurements (2003–2021) display decreases in ...
Shiv Priyam Raghuraman   +4 more
doaj   +1 more source

Review of the global models used within phase 1 of the Chemistry–Climate Model Initiative (CCMI)

open access: yes, 2017
We present an overview of state-of-the-art chemistry–climate and chemistry transport models that are used within phase 1 of the Chemistry–Climate Model Initia- tive (CCMI-1).
O. Morgenstern   +37 more
semanticscholar   +1 more source

Reciprocal control of viral infection and phosphoinositide dynamics

open access: yesFEBS Letters, EarlyView.
Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley   +1 more source

An unexpected alternative viologen electron mediator site in tungsten‐containing formate dehydrogenase

open access: yesFEBS Letters, EarlyView.
An unexpected alternative interaction site for ethyl viologen was identified in formate dehydrogenase 1 from Methylorubrum extorquens. Combined mutagenesis, kinetic analysis, and docking revealed that aromatic residues near an iron–sulfur cluster enable flavin mononucleotide‐independent electron transfer, offering a framework for engineering improved ...
Eleni G. Poloniataki, Yong Hwan Kim
wiley   +1 more source

Critical Southern Ocean climate model biases traced to atmospheric model cloud errors

open access: yesNature Communications, 2018
The Southern Ocean is a pivotal component of the global climate system yet it is poorly represented in climate models, with significant biases in upper-ocean temperatures, clouds and winds. Combining Atmospheric and Coupled Model Inter-comparison Project
P. Hyder   +23 more
semanticscholar   +1 more source

Epigenetic silencing of the liver‐specific lncRNA LUNAR promotes liver cancer progression via NOTCH activation

open access: yesMolecular Oncology, EarlyView.
LUNAR is a liver‐specific long noncoding RNA (lncRNA) that is highly expressed in normal liver but becomes epigenetically silenced in hepatocellular carcinoma through promoter hypermethylation. Loss of LUNAR is associated with NOTCH activation, epithelial–mesenchymal transition, and metastasis, whereas restoring LUNAR restrains metastatic progression ...
Se Ha Jang   +9 more
wiley   +1 more source

Climate change and climate modeling

open access: yesChoice Reviews Online, 2011
In long‐established fields like fluid mechanics or quantum theory, the contents of introductory textbooks are mostly predictable: The basics are covered in more or less the same order, and while cutting‐edge research occasionally gets a look‐in (depending on the inclinations of the authors), the contents are far more frequently reworkings of previous ...
openaire   +2 more sources

Projected Response of Tropical Cyclone Intensity and Intensification in a Global Climate Model

open access: yesJournal of Climate, 2018
As one of the first global coupled climate models to simulate and predict category 4 and 5 (Saffir–Simpson scale) tropical cyclones (TCs) and their interannual variations, the High-Resolution Forecast-Oriented Low Ocean Resolution (HiFLOR) model at the ...
Kieran Bhatia   +4 more
semanticscholar   +1 more source

Decreased cold‐sensing function of the transient receptor potential channel TRPM8 from tailed amphibians

open access: yesFEBS Open Bio, EarlyView.
Despite frogs avoiding low temperatures, examination of four salamander species revealed that none avoided cold and all possessed cold tolerance. Functional analysis of TRPM8, a cold sensor, showed that all salamander TRPM8s had lost their cold sensitivity.
Tadahiro Sawao   +3 more
wiley   +1 more source

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