Results 41 to 50 of about 15,738,050 (291)

Thirsty country: climate change and drought in Australia [PDF]

open access: yes, 2015
This report argues that climate change is likely making drought worse in the southeast and southwest of Australia, which are some of our most populous regions. Introduction Drought has deeply affected Australia throughout its history.
Climate Council
core  

Evaluating the effect of γ‐oryzanol on MASLD pathology using a medaka fish model

open access: yesFEBS Open Bio, EarlyView.
This study explores a liver disease called MASLD, which is increasing worldwide and can lead to serious damage. Researchers used medaka fish instead of rodents to test a food compound, γ‐oryzanol. Fish fed this compound had less liver fat and healthier gut bacteria.
Yukako Ito   +7 more
wiley   +1 more source

Greenhouse Gas Forcing and Climate Feedback Signatures Identified in Hyperspectral Infrared Satellite Observations

open access: yesGeophysical Research Letters, 2023
Global greenhouse gas forcing and feedbacks are the primary causes of climate change but have limited direct observations. Here we show that continuous, stable, global, hyperspectral infrared satellite measurements (2003–2021) display decreases in ...
Shiv Priyam Raghuraman   +4 more
doaj   +1 more source

Midwestern Regional Climate Center [PDF]

open access: yes, 2001
Made available in DSpace on 2016-11-14T22:36:27Z (GMT). No. of bitstreams: 2 ISWSIEM2001-01.pdf: 146176 bytes, checksum: 791a8da476fabb8bec8c3d10ae0a0993 (MD5) license.txt: 3973 bytes, checksum: 6c1c5beee39794d995a5ff442f5bd9ab (MD5) Previous issue ...
Midwestern Regional Climate Center
core  

The C‐terminal truncated splicing variant of NK1R negatively modulates substance P‐stimulated NK1R signaling

open access: yesFEBS Open Bio, EarlyView.
The neurokinin 1 receptor exists as full‐length (NK1L) and C‐terminally truncated (NK1S) splice variants. We show that NK1S heterodimerizes with NK1L, impairing Gαq coupling and Ca2+ mobilization while enhancing β‐arrestin1 recruitment. NK1S suppresses substance P‐driven gene expression and cell migration, revealing NK1S as an endogenous biased ...
Lan Phuong Nguyen   +8 more
wiley   +1 more source

IGF2 knockout reduces but does not abolish osteosarcoma growth in vitro and in vivo

open access: yesFEBS Open Bio, EarlyView.
To test whether endogenous IGF2 promotes osteosarcoma growth, IGF2 was knocked out in Saos2 cells via CRISPR‐Cas9. KO cells showed reduced proliferation in vitro, and knockout xenografts in mice reached only ~25% of wild‐type tumor volume. Insulin‐like growth factor 2 (IGF2) is implicated in osteosarcoma, but direct functional evidence of its role is ...
Shun Yao, Marco Archetti
wiley   +1 more source

Seasonal Climate Forecasts and Risk Management Among Georgia Farmers [PDF]

open access: yes, 2008
Recent increases in the scientific robustness of seasonal climate forecasts have not led to substantial changes in farmers’ risk management strategies of actors, largely because there is poor integration of scientific forecasting into farmers’ decision ...
Hoogenhoom, G.   +13 more
core  

The Role of Calcitonin Gene‐Related Peptide in High‐Altitude Headache: A Prospective Field Study

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective High‐altitude headache (HAH) is a common neurological condition associated with rapid ascent to high altitude. The pathophysiological mechanisms underlying HAH remain incompletely understood. Calcitonin gene‐related peptide (CGRP), a neuropeptide implicated in migraine pathophysiology, may play a key role in the pathophysiology of ...
Roman Schniepp   +4 more
wiley   +1 more source

Climate Change and Climate Modeling

open access: yesEos, Transactions American Geophysical Union, 2011
In long‐established fields like fluid mechanics or quantum theory, the contents of introductory textbooks are mostly predictable: The basics are covered in more or less the same order, and while cutting‐edge research occasionally gets a look‐in (depending on the inclinations of the authors), the contents are far more frequently reworkings of previous ...
openaire   +2 more sources

Going for zero: state decarbonisation strategies for prosperity in a zero-emission world [PDF]

open access: yes, 2015
This paper explains why states should have a decarbonisation strategy and explores some key policy elements. Abstract Across the world, governments at all levels are implementing policies to reduce carbon emissions, address local air pollution, improve
Climate Institute
core  

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