Results 31 to 40 of about 369,950 (266)

Characteristics and Preliminary Investigation of the Variations in the Activity of Tibetan Plateau Vortex in Summer under the Climate Warming

open access: yesGaoyuan qixiang
Using an objectively identified dataset of Tibetan Plateau Vortex (TPV) based on three reanalysis datasets and observations, combined with the Yearbook of TPV, this study analyzes the spatiotemporal variations of TPV activity from 1979 to 2022 and their ...
Zepeng TANG, Feimin ZHANG, Chenghai WANG
doaj   +1 more source

Model consensus projections of US regional hydroclimates under greenhouse warming

open access: yesEnvironmental Research Letters, 2019
We investigate ensemble-mean (‘consensus’) values of resolution-weighted CMIP5 multi-model simulations of 1976–2005 summer regional hydroclimates, and of their projected 2070–2099 changes under three progressively more severe representative concentration
Thomas J Phillips   +2 more
doaj   +1 more source

Greenhouse Gas Forcing and Climate Feedback Signatures Identified in Hyperspectral Infrared Satellite Observations

open access: yesGeophysical Research Letters, 2023
Global greenhouse gas forcing and feedbacks are the primary causes of climate change but have limited direct observations. Here we show that continuous, stable, global, hyperspectral infrared satellite measurements (2003–2021) display decreases in ...
Shiv Priyam Raghuraman   +4 more
doaj   +1 more source

An unexpected alternative viologen electron mediator site in tungsten‐containing formate dehydrogenase

open access: yesFEBS Letters, EarlyView.
An unexpected alternative interaction site for ethyl viologen was identified in formate dehydrogenase 1 from Methylorubrum extorquens. Combined mutagenesis, kinetic analysis, and docking revealed that aromatic residues near an iron–sulfur cluster enable flavin mononucleotide‐independent electron transfer, offering a framework for engineering improved ...
Eleni G. Poloniataki, Yong Hwan Kim
wiley   +1 more source

Decreased cold‐sensing function of the transient receptor potential channel TRPM8 from tailed amphibians

open access: yesFEBS Open Bio, EarlyView.
Despite frogs avoiding low temperatures, examination of four salamander species revealed that none avoided cold and all possessed cold tolerance. Functional analysis of TRPM8, a cold sensor, showed that all salamander TRPM8s had lost their cold sensitivity.
Tadahiro Sawao   +3 more
wiley   +1 more source

Why human connection is the true metric of research success

open access: yesFEBS Open Bio, EarlyView.
Human‐centred mentorship can be shaped by mentor attributes, actions, intrinsic drive and career ambition. Drawing on reflections across Singapore and France, as well as workshop insights from FEBS‐IUBMB ENABLE 2024, this article shows that human‐centred mentorship creates the conditions for sustainable growth, well‐being and retention in research ...
Timothy Lin Yun Tan   +3 more
wiley   +1 more source

Long‐term hippocampal alterations and cognitive impairment in a murine model of surgical sepsis

open access: yesFEBS Open Bio, EarlyView.
Using a mouse model of surgical sepsis, we tested long‐term memory and analyzed the transcriptome of single cells isolated from the hippocampus. Survivor mice showed worse memory, loss of certain brain cell subpopulations, and abnormal immune cell activity—suggesting that post‐sepsis brain alterations may be linked to cognitive deficits.
Dong Seong Cho   +4 more
wiley   +1 more source

Climate change and climate modeling

open access: yesChoice Reviews Online, 2011
In long‐established fields like fluid mechanics or quantum theory, the contents of introductory textbooks are mostly predictable: The basics are covered in more or less the same order, and while cutting‐edge research occasionally gets a look‐in (depending on the inclinations of the authors), the contents are far more frequently reworkings of previous ...
openaire   +2 more sources

Early Development and Tuning of a Global Coupled Cloud Resolving Model, and its Fast Response to Increasing CO2

open access: yesTellus: Series A, Dynamic Meteorology and Oceanography, 2022
Since the dawn of functioning numerical dynamical atmosphere- and ocean models, their resolution has steadily increased, fed by an exponential growth in computational capabilities.
Thorsten Mauritsen   +10 more
doaj   +1 more source

Pharmacological inhibition of the PERK pathway modulates hepatocellular carcinoma growth and immune signaling

open access: yesFEBS Open Bio, EarlyView.
Pharmacological inhibition of PERK in a DEN‐induced mouse model of liver cancer does not reduce tumor burden but alters cellular stress signaling. Despite blocking PERK activity, downstream stress responses, including CHOP expression, remain active, suggesting compensatory mechanisms within the unfolded protein response that may influence tumor ...
Ada Lerma‐Clavero   +5 more
wiley   +1 more source

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