Results 31 to 40 of about 369,950 (266)
Using an objectively identified dataset of Tibetan Plateau Vortex (TPV) based on three reanalysis datasets and observations, combined with the Yearbook of TPV, this study analyzes the spatiotemporal variations of TPV activity from 1979 to 2022 and their ...
Zepeng TANG, Feimin ZHANG, Chenghai WANG
doaj +1 more source
Model consensus projections of US regional hydroclimates under greenhouse warming
We investigate ensemble-mean (‘consensus’) values of resolution-weighted CMIP5 multi-model simulations of 1976–2005 summer regional hydroclimates, and of their projected 2070–2099 changes under three progressively more severe representative concentration
Thomas J Phillips +2 more
doaj +1 more source
Global greenhouse gas forcing and feedbacks are the primary causes of climate change but have limited direct observations. Here we show that continuous, stable, global, hyperspectral infrared satellite measurements (2003–2021) display decreases in ...
Shiv Priyam Raghuraman +4 more
doaj +1 more source
An unexpected alternative interaction site for ethyl viologen was identified in formate dehydrogenase 1 from Methylorubrum extorquens. Combined mutagenesis, kinetic analysis, and docking revealed that aromatic residues near an iron–sulfur cluster enable flavin mononucleotide‐independent electron transfer, offering a framework for engineering improved ...
Eleni G. Poloniataki, Yong Hwan Kim
wiley +1 more source
Despite frogs avoiding low temperatures, examination of four salamander species revealed that none avoided cold and all possessed cold tolerance. Functional analysis of TRPM8, a cold sensor, showed that all salamander TRPM8s had lost their cold sensitivity.
Tadahiro Sawao +3 more
wiley +1 more source
Why human connection is the true metric of research success
Human‐centred mentorship can be shaped by mentor attributes, actions, intrinsic drive and career ambition. Drawing on reflections across Singapore and France, as well as workshop insights from FEBS‐IUBMB ENABLE 2024, this article shows that human‐centred mentorship creates the conditions for sustainable growth, well‐being and retention in research ...
Timothy Lin Yun Tan +3 more
wiley +1 more source
Long‐term hippocampal alterations and cognitive impairment in a murine model of surgical sepsis
Using a mouse model of surgical sepsis, we tested long‐term memory and analyzed the transcriptome of single cells isolated from the hippocampus. Survivor mice showed worse memory, loss of certain brain cell subpopulations, and abnormal immune cell activity—suggesting that post‐sepsis brain alterations may be linked to cognitive deficits.
Dong Seong Cho +4 more
wiley +1 more source
Climate change and climate modeling
In long‐established fields like fluid mechanics or quantum theory, the contents of introductory textbooks are mostly predictable: The basics are covered in more or less the same order, and while cutting‐edge research occasionally gets a look‐in (depending on the inclinations of the authors), the contents are far more frequently reworkings of previous ...
openaire +2 more sources
Since the dawn of functioning numerical dynamical atmosphere- and ocean models, their resolution has steadily increased, fed by an exponential growth in computational capabilities.
Thorsten Mauritsen +10 more
doaj +1 more source
Pharmacological inhibition of PERK in a DEN‐induced mouse model of liver cancer does not reduce tumor burden but alters cellular stress signaling. Despite blocking PERK activity, downstream stress responses, including CHOP expression, remain active, suggesting compensatory mechanisms within the unfolded protein response that may influence tumor ...
Ada Lerma‐Clavero +5 more
wiley +1 more source

