Results 31 to 40 of about 293,074 (268)

Identifying the regional emergence of climate patterns in the ARISE-SAI-1.5 simulations

open access: yesEnvironmental Research Letters, 2023
Stratospheric aerosol injection is a proposed form of solar climate invention (SCI) that could potentially reduce the amount of future warming from externally-forced climate change. However, more research is needed, as there are significant uncertainties
Zachary M Labe   +2 more
doaj   +1 more source

Long-term latitudinal effects of precipitation change in global monsoon regions

open access: yesFrontiers in Earth Science, 2022
Global paleomonsoon precipitation evolution is confined to asynchronous responses to global monsoons to shared forcings, including summer insolation, sea surface temperature, atmospheric circulation coupling, and ocean circulation.
Wangting Ye   +4 more
doaj   +1 more source

Vegetation Effects on Air Pollution: A Comprehensive Assessment for Two Italian Cities

open access: yesAtmosphere
The role of urban vegetation in urban air quality is usually assessed by considering only the pollutant removal capacity of the plants. This study aims to show, for the first time, the effects of vegetation on air pollutant concentrations through its ...
Mihaela Mircea   +9 more
doaj   +1 more source

Cold waves are getting milder in the northern midlatitudes

open access: yesEnvironmental Research Letters, 2019
The strong two-day cold wave in the midwestern United States in January 2019 again ignited the discussion as to whether cold waves are getting more severe or not as a result of Arctic amplification due to climate change.
Geert Jan van Oldenborgh   +5 more
doaj   +1 more source

Neurocognitive, School‐Based, and Quality of Life Outcomes for Youth With Sickle Cell Disease and Thalassemia: A Scoping Review

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT The medical burdens of sickle cell disease (SCD) and transfusion‐dependent β‐thalassemia (TDT) are chronic and cumulative, even in children. Yet the effects expand beyond medications and healthcare visits due to their impacts on school attendance, academic performance, and peer engagement.
Mary Ann Etling   +2 more
wiley   +1 more source

Epigenetic silencing of the liver‐specific lncRNA LUNAR promotes liver cancer progression via NOTCH activation

open access: yesMolecular Oncology, EarlyView.
LUNAR is a liver‐specific long noncoding RNA (lncRNA) that is highly expressed in normal liver but becomes epigenetically silenced in hepatocellular carcinoma through promoter hypermethylation. Loss of LUNAR is associated with NOTCH activation, epithelial–mesenchymal transition, and metastasis, whereas restoring LUNAR restrains metastatic progression ...
Se Ha Jang   +9 more
wiley   +1 more source

Extracellular matrix remodeling and immune reprogramming drive residual tumor progression of liver cancer after incomplete microwave ablation

open access: yesMolecular Oncology, EarlyView.
Incomplete microwave ablation (iMWA) of liver cancer triggers a biphasic progression in residual tumors. At Day 3, the microenvironment is characterized by acute inflammatory responses and extracellular matrix (ECM) remodeling. By Day 14, a profound shift occurs toward oncogenic signal transduction and immunosuppression, marked by macrophage ...
Yu Liu   +9 more
wiley   +1 more source

Characterization of therapeutic antibodies targeting lymphatic and vascular resistance factor for the treatment of hypervascularized and highly metastatic cancers

open access: yesMolecular Oncology, EarlyView.
LVRF (lymphatic and vascular resistance factor) is a VEGFA splice variant upregulated in response to anti‐angiogenic therapy that fosters tumor adaptation through enhanced vascularization, lymphangiogenesis, and metastatic dissemination. Targeting LVRF with fully human neutralizing antibodies disrupts these processes and limits resistant tumor growth ...
Marion David   +12 more
wiley   +1 more source

Assimilation of SO2 TROPOMI Retrievals at the European Scale with EAKF Implemented in MINNI Through DART

open access: yesAtmosphere
Air quality modeling of sulfur dioxide (SO2) concentrations remains challenging due to the high variability of both natural and anthropogenic emission sources, as well as the complexities associated with its multiphase chemistry.
Giorgia De Moliner   +7 more
doaj   +1 more source

Evaluating the effect of γ‐oryzanol on MASLD pathology using a medaka fish model

open access: yesFEBS Open Bio, EarlyView.
This study explores a liver disease called MASLD, which is increasing worldwide and can lead to serious damage. Researchers used medaka fish instead of rodents to test a food compound, γ‐oryzanol. Fish fed this compound had less liver fat and healthier gut bacteria.
Yukako Ito   +7 more
wiley   +1 more source

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