Results 41 to 50 of about 271,979 (266)

Climate Change and Climate Modeling

open access: yesEos, Transactions American Geophysical Union, 2011
In long‐established fields like fluid mechanics or quantum theory, the contents of introductory textbooks are mostly predictable: The basics are covered in more or less the same order, and while cutting‐edge research occasionally gets a look‐in (depending on the inclinations of the authors), the contents are far more frequently reworkings of previous ...
openaire   +2 more sources

Epigenetic silencing of the liver‐specific lncRNA LUNAR promotes liver cancer progression via NOTCH activation

open access: yesMolecular Oncology, EarlyView.
LUNAR is a liver‐specific long noncoding RNA (lncRNA) that is highly expressed in normal liver but becomes epigenetically silenced in hepatocellular carcinoma through promoter hypermethylation. Loss of LUNAR is associated with NOTCH activation, epithelial–mesenchymal transition, and metastasis, whereas restoring LUNAR restrains metastatic progression ...
Se Ha Jang   +9 more
wiley   +1 more source

Long‐term hippocampal alterations and cognitive impairment in a murine model of surgical sepsis

open access: yesFEBS Open Bio, EarlyView.
Using a mouse model of surgical sepsis, we tested long‐term memory and analyzed the transcriptome of single cells isolated from the hippocampus. Survivor mice showed worse memory, loss of certain brain cell subpopulations, and abnormal immune cell activity—suggesting that post‐sepsis brain alterations may be linked to cognitive deficits.
Dong Seong Cho   +4 more
wiley   +1 more source

Risk and reward of the global truffle sector under predicted climate change

open access: yesEnvironmental Research Letters, 2022
Climate change has been described as the main threat for the cultivation and growth of truffles, but hydroclimate variability and model uncertainty challenge regional projections and adaptation strategies of the emerging sector.
Tomáš Čejka   +7 more
doaj   +1 more source

Pharmacological inhibition of the PERK pathway modulates hepatocellular carcinoma growth and immune signaling

open access: yesFEBS Open Bio, EarlyView.
Pharmacological inhibition of PERK in a DEN‐induced mouse model of liver cancer does not reduce tumor burden but alters cellular stress signaling. Despite blocking PERK activity, downstream stress responses, including CHOP expression, remain active, suggesting compensatory mechanisms within the unfolded protein response that may influence tumor ...
Ada Lerma‐Clavero   +5 more
wiley   +1 more source

Attribution of extreme rainfall from Hurricane Harvey, August 2017

open access: yesEnvironmental Research Letters, 2017
During August 25–30, 2017, Hurricane Harvey stalled over Texas and caused extreme precipitation, particularly over Houston and the surrounding area on August 26–28. This resulted in extensive flooding with over 80 fatalities and large economic costs.
Geert Jan van Oldenborgh   +9 more
doaj   +1 more source

Long-period changes of the air temperature in Tatarstan and their forecast till the end of the 21st century

open access: yesЖурнал Белорусского государственного университета: География, геология, 2019
Long-term changes in air temperature on the territory of the Republic of Tatarstan in the 20th–21st centuries are considered. The periods of unambiguous changes in the surface air temperature are determined.
Yuri P. Perevedentsev   +3 more
doaj   +1 more source

Carbon Dioxide Uptake by Mortars and Concretes Made with Portuguese Cements

open access: yesApplied Sciences, 2020
As the cement industry continues to address its role in the climate crisis, Portugal’s cement industry has started to calculate its net CO2 emissions to become an entirely carbon neutral sector.
Miguel Ángel Sanjuán   +3 more
doaj   +1 more source

Evaluating the effect of γ‐oryzanol on MASLD pathology using a medaka fish model

open access: yesFEBS Open Bio, EarlyView.
This study explores a liver disease called MASLD, which is increasing worldwide and can lead to serious damage. Researchers used medaka fish instead of rodents to test a food compound, γ‐oryzanol. Fish fed this compound had less liver fat and healthier gut bacteria.
Yukako Ito   +7 more
wiley   +1 more source

Detection of Forced Change Within Combined Climate Fields Using Explainable Neural Networks

open access: yesJournal of Advances in Modeling Earth Systems, 2022
Assessing forced climate change requires the extraction of the forced signal from the background of climate noise. Traditionally, tools for extracting forced climate change signals have focused on one atmospheric variable at a time, however, using ...
Jamin K. Rader   +3 more
doaj   +1 more source

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