Results 51 to 60 of about 271,979 (266)

Constraining CMIP6 estimates of Arctic Ocean temperature and salinity in 2025-2055

Frontiers in Marine Science, 2023
Global climate models (CMIP6 models) are the basis for future predictions and projections, but these models typically have large biases in their mean state of the Arctic Ocean.
Helene Reinertsen Langehaug, Hanne Sagen, A. Stallemo, Petteri Uotila, L. Rautiainen, Steffen Malskær Olsen, Marion Devilliers, Shuting Yang, E. Storheim   +8 more
doaj   +1 more source

A Depolarizing Leak in Sodium Bicarbonate Cotransporter NBCe1 Causes Brain Edema

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objectives SLC4A4 encodes electrogenic sodium bicarbonate cotransporter NBCe1, prominently expressed in kidney and brain. Recessive loss‐of‐function variants in SLC4A4 cause proximal renal tubular acidosis, no brain edema. In the brain, NBCe1 is expressed by astrocytes, where it regulates pH and mediates astrocyte volume changes.
Quinty Bisseling, Mark D. Parker, Sven Kerst, Richard A. Pasternack, Jacob Tondreau, Marjolein Breur, Gemma M. van Rooijen‐van Leeuwen, Davide Tonduti, Ettore Salsano, Alejandra Darling, Joanna A. E. van Wijk, Susanna Törnroth‐Horsefield, Marianna Bugiani, Petra J. W. Pouwels, Quinten Waisfisz, Marjo S. van der Knaap, Rogier Min   +16 more
wiley   +1 more source

The surface impacts of Arctic stratospheric ozone anomalies

Environmental Research Letters, 2014
In the Arctic stratosphere, total column ozone in the spring can vary, from year to year, by as much as 30%. This large interannual variability, however, is absent from many present-generation climate models, in which the prescribed seasonal cycle of ...
K L Smith, L M Polvani
doaj   +1 more source

The Role of Calcitonin Gene‐Related Peptide in High‐Altitude Headache: A Prospective Field Study

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective High‐altitude headache (HAH) is a common neurological condition associated with rapid ascent to high altitude. The pathophysiological mechanisms underlying HAH remain incompletely understood. Calcitonin gene‐related peptide (CGRP), a neuropeptide implicated in migraine pathophysiology, may play a key role in the pathophysiology of ...
Roman Schniepp, Ludwig Karrasch, Helena Breitenstein, Andreas Straube, Katharina Kamm   +4 more
wiley   +1 more source

Effects of Pacific Intertropical Convergence Zone precipitation bias on ENSO phase transition

Environmental Research Letters, 2014
In this study, the effect of mean precipitation bias over the Pacific Intertropical Convergence Zone (ITCZ) on the El Niño southern oscillation (ENSO) transition is examined using CMIP3 and CMIP5 archives.
Yoo-Geun Ham, Jong-Seong Kug
doaj   +1 more source

Relationship Between Neurologic Symptoms and Signs and FMR1 Genotype in Premutation Carriers

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background and Objectives Fragile X‐associated Tremor/Ataxia Syndrome (FXTAS) is the most severe late‐onset condition caused by a premutation in the FMR1 gene, characterized by expanded CGG triplet repeats of 55–200. Clinical presentations of FXTAS, including gait ataxia, kinetic tremor, cognitive decline, and rare Parkinsonism, are linked to ...
Flora Tassone, Freddy Chafota, Miguel E. Rentería, Randi J. Hagerman, Ellery Santos, Anna Atkinson, Nicholas G. Martin, Elsdon Storey, Danuta Z. Loesch   +8 more
wiley   +1 more source

Advancing Age Modulates Associations Between Cognitive Impairment and Brain Volumes in Early MS

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Introduction Cognitive impairment is common in multiple sclerosis (MS), but manifestations following the first demyelinating event are relatively unexplored. We investigated cross‐sectional associations between magnetic resonance imaging (MRI)–derived brain volumes and the presence of cognitive impairment outcomes five years after the first ...
Piriyankan Ananthavarathan, Marco Pitteri, Michael Foster, Sara Collorone, Sara Salama, Elisa Colato, Ferran Prados, Baris Kanber, Marios Yiannakas, Claudia A. M. Gandini Wheeler‐Kingshott, Indran Davagnanam, Frederik Barkhof, Declan Chard, Olga Ciccarelli, Ahmed Toosy   +14 more
wiley   +1 more source

Model performance and surface impacts of atmospheric river events in Antarctica

Discover Atmosphere
There is increasing evidence that atmospheric rivers (ARs) drive extreme precipitation and melt events across Antarctica and that these impacts are more accurately captured in high-resolution models.
Marlen Kolbe, Jose Abraham Torres Alavez, Ruth Mottram, Richard Bintanja, Eveline C. van der Linden, Martin Stendel   +5 more
doaj   +1 more source

Comparing the Effect of Semi‐Immersive Virtual Reality, Computerized Cognitive Training, and Traditional Rehabilitation on Cognitive Function in Multiple Sclerosis: A Randomized Clinical Trial

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Cognitive impairment is a common non‐motor symptom in Multiple Sclerosis (MS), negatively affecting autonomy and Quality of Life (QoL). Innovative rehabilitation strategies, such as semi‐immersive virtual reality (VR) and computerized cognitive training (CCT), may offer advantages over traditional cognitive rehabilitation (TCR ...
Maria Grazia Maggio, Desiree Latella, Lilla Bonanno, Paulo Cezar Rocha dos Santos, Marcos Maldonado‐Díaz, Meir Plotnik, Rosaria De Luca, Angelo Quartarone, Rocco Salvatore Calabrò   +8 more
wiley   +1 more source

Atmospheric rivers and winter sea ice drive recent reversal in Antarctic ice mass loss

Communications Earth & Environment
Since about 2000, the total mass of the Antarctic Ice Sheet has declined at a near-linear rate, increasing global sea levels. Since 2016, however, satellite gravimetry data reveal a slowdown in net Antarctic ice mass loss and a net mass gain since 2020 ...
Marlen Kolbe, Jose Abraham Torres Alavez, Ruth Mottram, Marwan Katurji, Richard Bintanja, Eveline C. van der Linden   +5 more
doaj   +1 more source