Results 111 to 120 of about 840,709 (301)

Fibronectin1‐Expressing Subicular Circuits Selectively Govern the Retrieval of Novel Object Recognition

Advanced Science, EarlyView.
Fibronectin 1 (FN1)‐expressing subicular subpopulations encode novel object preference and selectively govern retrieval of novel object recognition (NOR) via affecting excitability of entorhinal‐projecting circuit through large conductance Ca2+‐activated potassium (BK) channel. ABSTRACT Novel object recognition (NOR), referring to the cognitive ability
Fan Fei, Jiaying Shi, Jing Xi, Yixiang Xu, Shuye Ying, Xukun Fan, Wangjialu Lu, Zhisheng Li, Menghan Li, Yu Wang, Li Cheng, Lin Yang, Lingyu Xu, Zhong Chen, Cenglin Xu, Yi Wang   +15 more
wiley   +1 more source

Comparison of GLMM, RF and XGBoost Methods for Estimating Daily Relative Humidity in China Based on Remote Sensing Data

Remote Sensing
Relative humidity (RH) is an important meteorological factor that affects both the climate system and human activities. However, the existing observational station data are insufficient to meet the requirements of regional scale research.
Ying Yao, Ling Wu, Hongbo Liu, Wenbin Zhu   +3 more
doaj   +1 more source

Increased insolation threshold for runaway greenhouse processes on Earth like planets

, 2013
Because the solar luminosity increases over geological timescales, Earth climate is expected to warm, increasing water evaporation which, in turn, enhances the atmospheric greenhouse effect.
A Arking, A Borysow, A Bucholtz, Alizée Pottier, AP Ingersoll, B Charnay, B Van Leer, Benjamin Charnay, BJ Soden, C Goldblatt, C Goldblatt, C Richard, DMW Frierson, DO Gough, E Wolf, F Forget, F Forget, F Hourdin, F Selsis, Francois Forget, G Le Hir, GC Simpson, GL Mellor, H Le Treut, J Leconte, J Yang, JE Hansen, JF Kasting, JF Kasting, JF Kasting, Jérémy Leconte, LS Rothman, M Ishiwatari, M Komabayashi, O Boucher, OB Toon, R Wordsworth, R Wordsworth, RD Wordsworth, RK Kopparapu, Robin Wordsworth, RT Pierrehumbert, RT Pierrehumbert, RT Pierrehumbert, S Clough, S Manabe, S Nakajima, SC Sherwood, V Ramanathan, Y Abe   +49 more
core   +4 more sources

Targeting the PDK1/c‐Myc/SOX10 Signaling in Oligodendrocytes Alleviates Neuropathic Pain

Advanced Science, EarlyView.
This work reveals that oligodendrocyte homeostasis, mediated by PDK1, is a critical determinant of neuropathic pain (NPP) pathogenesis. Disruption of PDK1 in oligodendrocytes impairs SOX10‐dependent myelination programs through c‐Myc accumulation, leading to disrupted myelination and the pathophysiology of NPP.
Pingping Qiao, Lifang Guo, Guochao Yang, Chaoli Huang, He Wang, Jian‐Jun Yang, Guiquan Chen, Yimin Hu   +7 more
wiley   +1 more source

Certain questions of the acclimatization of construction workers to the conditions of a subtropical climate [PDF]

The period of active acclimatization was determined for construction workers coming into a subtropical climate. Changes were observed in metabolic processes, oxygen needs, pulse rate, arterial pressure, body and skin temperature, body weight, water ...
Babayev, A.
core   +1 more source

Dissecting the Ecological Structure of Health and Disease in the Global Gut Microbiome

Advanced Science, EarlyView.
We introduce Wiredancer, a framework that identifies three continuous ecological factors of the gut microbiota. These factors exhibit distinct patterns across health and disease, jointly capturing disrupted ecological stability and offering a new perspective for precision diagnostics and therapeutic strategies.
Baoyuan Zhu, Shuhao Chen, Yunheng Diao, Wei Wang, Yuanyuan Huang, Liqin Liang, Xiaodan Lu, Rui Han, Minxin Guo, Zhaobo Li, Shuhong Wang, Hehua Li, Chenyu Liu, Jing Zhou, Dongsheng Xiong, Xiaobo Li, Yuping Ning, Xuetao Shi, Fengchun Wu, Kai Wu   +19 more
wiley   +1 more source

BLADE‐ON‐PETIOLE Genes Enable Genetic Bottleneck Mitigation Through Cross‐Species Repurposing of Floral Persistence Traits

Advanced Science, EarlyView.
This study shows that BLADE‐ON‐PETIOLE (BOP) proteins regulate floral abscission and senescence in tomato by interacting with TFAM1 to form transcriptional condensates controlling the ARABIDOPSIS THALIANA HOMEOBOX GENE 1 (ATH1)‐mediated abscission pathway.
Nan Xiao, Qianwen Lyu, Tinghao Zhang, Yupan Zou, Yue Xie, Dandan Yang, Cao Xu, Xiaozhen Huang   +7 more
wiley   +1 more source

Altitude, latitude and climate zone as determinants of mountain hare (Lepus timidus) coat colour change. [PDF]

Ecol Evol, 2023
Stokes AW, Hofmeester TR, Thorsen NH, Odden J, Linnell JDC, Pedersen S.   +5 more
europepmc   +1 more source

Gemella morbillorum Promotes Colorectal Carcinogenesis: LPBDCP‐Mediated Invasion Activates Ras Signaling and Destabilizes p53

Advanced Science, EarlyView.
ABSTRACT Gut microbiota dysbiosis promotes colorectal cancer (CRC) tumorigenesis. A global fecal metagenomic analysis identified Gemella morbillorum as a key contributor to the CRC‐associated microbiota. Fluorescence in situ hybridization revealed that Gemella morbillorum is enriched in CRC tumor tissues compared to adjacent normal tissues.
Zhen Wang, Jia Zhang, Haojie Lu, Jingjing Ni, Shuaishuai Yang, Yuting Shi, Shuo Zhang, Pei Zhang, Li Liu   +8 more
wiley   +1 more source

Greenness and excess deaths from heat in 323 Latin American cities: Do associations vary according to climate zone or green space configuration? [PDF]

Environ Int, 2023
Schinasi LH, Bakhtsiyarava M, Sanchez BN, Kephart JL, Ju Y, Arunachalam S, Gouveia N, Teixeira Caiaffa W, O'Neill MS, Dronova I, Diez Roux AV, Rodriguez DA.   +11 more
europepmc   +1 more source