Metabolic dysfunction‐associated steatotic liver disease (MASLD) affects nearly one‐third of the global population and poses a significant risk of progression to cirrhosis or liver cancer. Here, we discuss the roles of hepatic dendritic cell subtypes in MASLD, highlighting their distinct contributions to disease initiation and progression, and their ...
Camilla Klaimi+3 more
wiley +1 more source
Insights into PI3K/AKT signaling in B cell development and chronic lymphocytic leukemia
This Review explores how the phosphoinositide 3‐kinase and protein kinase B pathway shapes B cell development and drives chronic lymphocytic leukemia, a common blood cancer. It examines how signaling levels affect disease progression, addresses treatment challenges, and introduces novel experimental strategies to improve therapies and patient outcomes.
Maike Buchner
wiley +1 more source
Tree pruning/inspection robot climbing mechanism design, kinematics study and intelligent control : a thesis presented in partial fulfilment of the requirements for the degree of Doctor of Philosophy in Mechatronics at Massey University, Manawatu Campus, New Zealand [PDF]
Forestry plays an important role in New Zealand’s economy as its third largest export earner. To achieve New Zealand Wood Council’s export target of $12 billion by 2022 in forest and improve the current situation that is the reduction of wood harvesting ...
Gui, Pengfei
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El rol de la inteligencia emocional en el rendimiento en escalada [PDF]
Purpose: To investigate the association between emotional intelligence (EI) and self-reported climbing ability. Methods: Redpoint climbing ability was used as an indicator of rock climbing performance and EI were assessed as ability and a trait using ...
España Romero, Vanesa+1 more
core +2 more sources
The power of microRNA regulation—insights into immunity and metabolism
MicroRNAs are emerging as crucial regulators at the intersection of metabolism and immunity. This review examines how miRNAs coordinate glucose and lipid metabolism while simultaneously modulating T‐cell development and immune responses. Moreover, it highlights how cutting‐edge artificial intelligence applications can identify miRNA biomarkers ...
Stefania Oliveto+2 more
wiley +1 more source
Lean - Mean: Tree climbing machine! [PDF]
Staying fit and healthy is essential if you are planning a long and productive climbing career. Keys to maintaining good fitness and health, along with treating injuries carefully will be discussed in this interactive session.
Harrison, Andrew
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The use of clamping grips and friction pads by tree frogs for climbing curved surfaces [PDF]
Most studies on the adhesive mechanisms of climbing animals have addressed attachment against flat surfaces, yet many animals can climb highly curved surfaces, like twigs and small branches.
Barnes, W. Jon P.+7 more
core +2 more sources
Social context prevents heat hormetic effects against mutagens during fish development
This study shows that sublethal heat stress protects fish embryos against ultraviolet radiation, a concept known as ‘hormesis’. However, chemical stress transmission between fish embryos negates this protective effect. By providing evidence for the mechanistic molecular basis of heat stress hormesis and interindividual stress communication, this study ...
Lauric Feugere+5 more
wiley +1 more source
COMPETITIVE ABILITY OF MAIZE IN MIXTURE WITH CLIMBING BEAN IN ORGANIC FARMING [PDF]
Intercropped crops represent an important production system in organic farming, especially maize/climbing bean mixture due to its high content of protein in bean seeds for human diet, and producing silage for ruminants.
Bavec, Franc+4 more
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