Results 41 to 50 of about 146,241 (297)

The relation of stair climbing behaviors with developing poor health outcomes in knee osteoarthritis

, 2023
White, Daniel K.Knee osteoarthritis (OA) impacts over 250 million adults worldwide and is a leading cause of functional limitation in older adults, such as slow walking or difficulty getting up from a chair.
Jakiela, Jason Thomas
core   +1 more source

Sport climbing competence is influenced by training frequency, experience, self-efficacy, flow, and emotional intelligence

Frontiers in Psychology
Sport climbing requires the integration of physical and cognitive abilities. The Embodied Cognition (EC) theoretical framework is increasingly applied in recreational sport research, as it emphasizes the influence of bodily experience on cognition ...
Marina Turchetto, Valentina Tomaselli, Francesca Giorgi, Silvia Leone, Irene Leo   +4 more
doaj   +1 more source

Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential

FEBS Letters, EarlyView.
Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta, Hari Baskar Balasubramanian, Amir Pasokh, Marietta Zille   +3 more
wiley   +1 more source

Climbing behavior by mice as an endpoint for preclinical assessment of drug effects in the absence and presence of pain

Frontiers in Pain Research, 2023
This study evaluated climbing in mice as a tool to assess the expression and treatment of pain-related behavioral depression in male and female ICR mice.
Edna J. Santos, Arianna N. Giddings, Farah A. Kandil, S. Stevens Negus   +3 more
doaj   +1 more source

An epithelial GPR35 isoform supports tumor‐associated transcriptional and metabolic phenotypes

FEBS Letters, EarlyView.
GPR35 generates two functionally distinct isoforms with previously unresolved roles. GPR35‐short mediates immune‐cell chemotaxis, while GPR35‐long is enriched in colorectal cancer epithelium, where it supports increased metabolism, proliferation, and tumor‐associated transcriptional programs.
Jørgen D. Rønneberg, Martine Hjeltnes, Josephine Krieger, Joshua E. Elias, Maria Stensland, Kristian Holm, Xiaojun Jiang, Chuki Khangsar, Tuula A. Nyman, Arthur Kaser, Johannes R. Hov, Tom H. Karlsen, Nicole C. Kaneider, Frode L. Jahnsen, Georg Schneditz   +14 more
wiley   +1 more source

Design and development of a pole climbing surveillance robot

, 2011
The cost of installing, monitoring and servicing a fixed camera system can be high and not all areas are in need of constant surveying. The increase in crime in urban areas emphasizes the need for a more effective and efficient surveillance system, as a ...
Barlow, Chris, Prior, Stephen D., Bell, Jonathon, Odedra, Sid, Erbil, Mehmet Ali, Karamanoglu, Mehmet   +5 more
core   +1 more source

Affordance Realization in Climbing: Learning and Transfer

Frontiers in Psychology, 2018
The aim of this study was to investigate how the affordances of an indoor climbing wall changed for intermediate climbers following a period of practice during which hold orientation was manipulated within a learning and transfer protocol.
Ludovic Seifert, Dominic Orth, Bruno Mantel, Jérémie Boulanger, Romain Hérault, Matt Dicks   +5 more
doaj   +1 more source

Sport and adventure in the Pădurea Craiului Mountains [PDF]

GeoSport for Society, 2019
The term of tourist product, as it was understood in the first decade after December, has undergone an important change of meaning, in the age of today’s tourist.
Varodi Mihaela OLĂU, Dana Ioana CRISTEA , Anca-Cristina POP, Maria GOZNER   +3 more
doaj   +1 more source

Kinematics and Aerodynamics of Dragonflies (Pantala flavescens, Libellulidae) in Climbing Flight

Frontiers in Bioengineering and Biotechnology, 2022
This study presents a detailed analysis of dragonflies’ climbing flight by integratinghigh-speed photogrammetry, three-dimensional reconstruction, and computational fluid dynamics.
Liansong Peng, Tianyu Pan, Mengzong Zheng, Shiying Song, Guanting Su, Qiushi Li, Qiushi Li, Qiushi Li   +7 more
doaj   +1 more source

Nutrient/TOR signaling controls adipose mitochondrial transcription factor A (TFAM) to regulate organismal growth in Drosophila

FEBS Letters, EarlyView.
Animals must match their growth rate to available nutrients. We show that in Drosophila larvae, the nutrient‐sensing TOR kinase controls growth by regulating levels of TFAM, a key regulator of mitochondrial function, in the adipose tissue. When nutrients are abundant, high TOR activity suppresses TFAM, lowering mitochondrial bioenergetic activity and ...
Shrivani Sriskanthadevan‐Pirahas, Shahoon Khan, Abhishek Sharma, Byoungchun Lee, Savraj S. Grewal   +4 more
wiley   +1 more source