Results 61 to 70 of about 457,059 (295)

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Moisture tempers impairment of adult Otiorhynchus sulcatus (Coleoptera: Curculionidae) climbing ability by fluoropolymer, talc dust, and lithium grease [PDF]

, 2005
As part of a project to develop tools for the physical exclusion of flightless root weevils, adult black vine weevils (BVW), Otiorhynchus sulcatus (F.), were placed in open enclosures with smooth walls of glass, plastic or aluminum to test their ability ...
Bomford, Michael K., Vernon, Robert S.
core   +1 more source

CMB Imprints of a Pre-Inflationary Climbing Phase [PDF]

, 2012
We discuss the implications for cosmic microwave background (CMB) observables, of a class of pre-inflationary dynamics suggested by string models where SUSY is broken due to the presence of D-branes and orientifolds preserving incompatible portions of it.
, A Sagnotti, A. Fialkov, A. Kashlinsky, A. Kashlinsky, A. Sagnotti, A. Sen, B. Rathaus, C. Burgess, C. Cheung, C.J. Copi, D.E. Kaplan, D.H. Lyth, D.S. Gorbunov, E Dudas, E. Dudas, E. Kiritsis, E. Ramirez, E. Ramirez, E.D. Kovetz, F. Strocchi, for reviews see E. Dudas, G. Aldazabal, I.P. Heard, J. Polchinski, K. Becker, L. Covi ., L. Keldysh, L. Keldysh, M. Abramowitz, M. Cicoli, M. Cicoli, M. Gomez-Reino, M.B. Green, N Kitazawa, N. Arkani-Hamed, N. Itzhaki, P.K. Townsend, R. Emparan, S. Kachru, S. Kundu, S. Weinberg, S.P Patil, S.Yu. Slavyanov, WMAP collaboration   +44 more
core   +3 more sources

Identification of serum protein biomarkers for pre‐cancerous lesions associated with pancreatic ductal adenocarcinoma

Molecular Oncology, EarlyView.
This work identified serum proteins associated with pancreatic epithelial neoplasms (PanINs) and early‐stage PDAC. Proteomics screens assessed genetically engineered mice with abundant PanINs, KPC mice (Lox‐STOP‐Lox‐KrasG12D/+ Lox‐STOP‐Lox‐Trp53R172H/+ Pdx1‐Cre) before PDAC development and also early‐stage PDAC patients (n = 31), compared to benign ...
Hannah Mearns, Jaclyn S. Long, Sergio Lilla, Kelly Hodge, Marcus J. G. W. Ladds, Colin Nixon, Paula Fernández‐Palanca, Sara Zanivan, Pilar Acedo, Stephen P. Pereira, Kevin M. Ryan   +10 more
wiley   +1 more source

Genetic attenuation of ALDH1A1 increases metastatic potential and aggressiveness in colorectal cancer

Molecular Oncology, EarlyView.
Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova, Zuzana Kozovska, Ondrej Pos, Kristina Pavlov, Sachin Gulati, Peter Makovicky, Kristina Jakic, Monika Burikova, Eva Sedlackova, Barbora Svitkova, Silvia Tyciakova, Vojtech Bystry, Nicolas Blavet, Boris Tichy, Matej Hrnciar, Jaroslav Budis, Miroslav Tomas, Peter Dubovan, Georgina Kolnikova, Veronika Repaska, Nikoleta Mojzesova, Eva Zomborska, Daniel Pindak, Michal Mego, Tomas Szemes, Miroslava Matuskova   +25 more
wiley   +1 more source

Kinetic simulations of ladder climbing by electron plasma waves [PDF]

, 2017
The energy of plasma waves can be moved up and down the spectrum using chirped modulations of plasma parameters, which can be driven by external fields. Depending on whether the wave spectrum is discrete (bounded plasma) or continuous (boundless plasma),
Barth, Ido, Dodin, I. Y., Fisch, N. J., Hara, Kentaro, Kaminski, Erez   +4 more
core   +3 more sources

COMP–PMEPA1 axis promotes epithelial‐to‐mesenchymal transition in breast cancer cells

Molecular Oncology, EarlyView.
This study reveals that cartilage oligomeric matrix protein (COMP) promotes epithelial‐to‐mesenchymal transition (EMT) in breast cancer. We identify PMEPA1 (protein TMEPAI) as a novel COMP‐binding partner that mediates EMT via binding to the TSP domains of COMP, establishing the COMP–PMEPA1 axis as a key EMT driver in breast cancer.
Konstantinos S. Papadakos, Gilar Gorji‐bahri, Lejla Gradjan, Julia Zajac, Kacper Gil, Yvonne Thokozile Nduku, Anna M. Blom   +6 more
wiley   +1 more source

EDNRB‐dependent endothelin signaling reduces proliferation and promotes proneural‐to‐mesenchymal transition in gliomas

Molecular Oncology, EarlyView.
Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau, Leonor Garcia, Hugo Arnold, Antonija Hanžek, Maialen Arrieta, Laurent R Gauthier, Christine Granotier‐Beckers, François D Boussin, Amaury Herbet, Marie Hautière, Valentin Asei‐Ceschino, Clémentin Jacques, Laura Brard, Thomas Harnois, Valérie Coronas, Bruno Constantin, Aurélien Chatelier, Jean Chemin, Serge Urbach, Martial Seveno, Szimonetta Hideg, Chantal Ripoll, Kasandra Aguilar‐Cázarez, Min Zheng, Guo‐Hao Huang, Sheng‐Qing Lv, Lei Zhang, Philippe Rondard, Laurent Prezeau, Jean‐Philippe Pin, Hugues Duffau, Luc Bauchet, Valérie Rigau, Franck Denat, Charles Truillet, Didier Boquet, Jean‐Philippe Hugnot   +36 more
wiley   +1 more source

Work hands and feet in motion on the vertical ladder into the prosthesis disabled lower limb [PDF]

Pedagogìka, Psihologìâ ta Mediko-bìologìčnì Problemi Fìzičnogo Vihovannâ ì Sportu, 2012
The influence of the conditions of ascent and descent on the stairs with disabilities is shown. The study involved 12 persons with lower limb prosthetic right or left foot.
Li Yugang, Ma Haozhe, Chen Jian, Xia Yu
doaj  

Median computation in graphs using consensus strategies [PDF]

Following the Majority Strategy in graphs, other consensus strategies, namely Plurality Strategy, Hill Climbing and Steepest Ascent Hill Climbing strategies on graphs are discussed as methods for the computation of median sets of profiles.
Balakrishnan, K., Changat, M., Mulder, H.M.   +2 more
core   +1 more source