Results 71 to 80 of about 87,946 (258)

Early‐life high‐fat diet exposure increases Achilles tendon stiffness and induces transcriptomic alterations

open access: yesFEBS Open Bio, EarlyView.
Early‐life exposure to a high‐fat diet altered intact Achilles tendons in rat offspring, making them thinner, stiffer, and molecularly distinct even without injury. These findings suggest that developmental high‐fat diet exposure may impair tendon quality and increase susceptibility to mechanical overload or tendon injury later in life.
Heyong Yin   +3 more
wiley   +1 more source

Pull-Up Performance Is Affected Differently by the Muscle Contraction Regimens Practiced during Training among Climbers

open access: yesBioengineering
Sport climbing performance is highly related to upper limb strength and endurance. Although finger-specific methods are widely analyzed in the literature, no study has yet quantified the effects of arm-specific training.
Laurent Vigouroux, Marine Devise
doaj   +1 more source

RoundMi: A quantitative method to analyze mitochondrial morphology in mitotic cells

open access: yesFEBS Open Bio, EarlyView.
RoundMi is a workflow for rapid analysis of mitochondrial morphology in mitotic cells. By combining adaptive preprocessing with automated segmentation and quantification, it enables accurate measurements from single focal plane images, reducing acquisition time and computational demands while remaining compatible with high‐throughput fixed and live ...
Elmira Parvindokht Bararpour   +2 more
wiley   +1 more source

Effect of an indoor climbing program on selective attention of children with autism spectrum disorder (ASD)

open access: yesHuman Movement
Purpose Children with autism spectrum disorder (ASD) focus their attention more easily through visual support. Indoor climbing requires focus and motor planning that enhance the cognitive functions and attention of children with ASD to follow specific ...
Alexandra Eleftheria Broupi   +3 more
doaj   +1 more source

Cyclic azapeptide CD36 ligand attenuates cardiac injury and reduces long‐chain fatty acid accumulation after myocardial ischemia–reperfusion in mice

open access: yesFEBS Open Bio, EarlyView.
In a murine model of myocardial ischemia and reperfusion (MI/R), the CD36 azapeptide ligand MPE‐298 reduces cardiac injury and transiently lowers left ventricular long‐chain fatty acids (LCFAs) accumulation 3 h after reperfusion, accompanied by a decrease of oxidative stress and inflammation‐associated genes' expression in the heart and adipose tissue.
Jade Gauvin   +12 more
wiley   +1 more source

The art of falling: identifying the falls scenarios associated with bouldering injuries

open access: yesFrontiers in Sports and Active Living
IntroductionBouldering has seen a significant rise in popularity, accompanied by an increase in related injuries, primarily caused by falls. To enhance prevention strategies and improve protective mats, it is crucial to understand the mechanisms behind ...
Erwan Beurienne   +9 more
doaj   +1 more source

Hydrostatic pressure activates HIF‐1α via β‐catenin to promote stemness in breast cancer cells

open access: yesFEBS Open Bio, EarlyView.
To mimic the elevated intestinal fluid pressure in breast cancers, we loaded human breast cancer cells (MCF‐7, MDA‐MB‐453, and BT‐474) to 50 mmHg hydrostatic pressure. Hydrostatic pressure exposure upregulated HIF‐1α and induced stemness in MCF‐7 and BT‐474 cells.
Da Zhai   +8 more
wiley   +1 more source

Comparison of Finger Flexor Strength and Muscle Quality Between Climbers and Non-Climbers: Influence of Sex and Grip Type

open access: yesApplied Sciences
Climbing demands exceptional isometric finger flexor strength and neuromuscular efficiency. This study aimed to compare maximum isometric strength and muscle quality (MQ) between climbers and non-climbers and examine the influence of sex and specific ...
Diego González-Martín   +4 more
doaj   +1 more source

Hyperactive ice‐binding proteins stabilize cell membranes and improve resistance to dehydration stress in Caenorhabditis elegans

open access: yesFEBS Open Bio, EarlyView.
TisIBP8, a fungal‐derived hyperactive ice‐binding protein, helps Caenorhabditis elegans survive dehydration. It localizes near cell membranes, reduces cell damage, and helps maintain membrane structure during drying. These results suggest that ice‐binding proteins can protect cells from dehydration stress as well as freezing stress.
Daiki Shimose   +9 more
wiley   +1 more source

Zoborg: On‐Demand Climbing Control for Cyborg Beetles

open access: yesAdvanced Science
Transitioning from horizontal surfaces to vertical walls is crucial for terrestrial robots to navigate complex environments. Replicating such impressive surface transitions in artificial insect‐scale robots has been particularly challenging.
Lachlan Fitzgerald   +5 more
doaj   +1 more source

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