Results 71 to 80 of about 146,241 (297)
Journal of Functional Morphology and KinesiologyBackground/Objectives: Rock climbing is a multifaceted athletic activity that requires both psychological and physiological resilience. This study aimed to examine the differences in psychological factors and fatigue predictors between novice and ...
Alejandro Padilla-Crespo +2 more
doaj +1 more source
Oncogenic DMTF1β promotes cancer cell motility by regulating autophagy through ULK1 stabilization
Molecular Oncology, EarlyView.In the current study, we demonstrate that the oncogene DMTF1β regulates ULK1 stability by reducing its proteasomal degradation in cancer cells. This stabilization enables ULK1 to induce autophagy, which in turn facilitates cancer cell migration. Consequently, reduced DMTF1β levels lead to decreased autophagy and impaired cancer cell migration.
Jun Xu +13 more
wiley +1 more source
Dietary Intake, Body Composition and Iron Status in Experienced and Elite Climbers
Frontiers in Nutrition, 2020 Climbing has developed into a popular recreational and elite sport, evidenced by a growing number of licenced competition athletes, and the acceptance into the Olympic calendar for Tokyo 2020.
Edward Gibson-Smith +2 more
doaj +1 more source
Loss of proton‐sensing TDAG8 increases tumor progression in mouse models of colon cancer
Molecular Oncology, EarlyView.Loss of the pH‐sensing receptor TDAG8 accelerates colorectal cancer progression in mice. Animals lacking TDAG8 expression had increased tumor growth, DNA damage, and recruitment of tumor‐associated immune cells, including macrophages, neutrophils, and monocytes.
Ermanno Malagola +11 more
wiley +1 more source
Molecular Oncology, EarlyView.Matched spatial transcriptomics and single‐nuclei RNA‐seq were generated for anaplastic and BRAFV600E papillary thyroid cancers revealing generic and tumor‐specific states occurring in cancer cells and in the tumor microenvironment. In this context, cancer dedifferentiation mirrored organoid maturation through ordered thyroid marker gain/loss ...
Adrien Tourneur +11 more
wiley +1 more source
, 2016 The chapter, "Physiology of climbing" was written by the listed authors including Luisa V. Giles (Douglas College Faculty). This is the first book to explore in depth the science of climbing and mountaineering.
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On parallels and differences between clitic climbing and long scrambling & the economy of derivations [PDF]
, 1995 In this paper I show that Clitic Climbing (CC) in Spanish and Long Scrambling (LS) in German (and Polish) are (im-)possible out of the same environments.
Sabel, Joachim
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Human impact on the vegetation of limestone cliffs in the northern Swiss Jura mountains [PDF]
, 2006 Cliffs provide unique habitats for many specialised organisms, including chamaephytes and slowly growing trees. Drought, high temperature amplitude, scarcity of nutrients and high insolation are general characteristics of exposed limestone cliff faces.
Müller, Stefan
core +1 more source
A modular leightweight construction system for climbing robots
, 2022 S.15-19State of the art climbing robots are highly sophisticated robotic devices that have been engineered for one very specific task. This is one reason why climbing robots have not been able to penetrate the service market which demands customized but ...
Wolf, A., Schmierer, G., Schraft, R.D.
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CEACAM1 participation in breast cancer progression
Molecular Oncology, EarlyView.In invasive breast cancer (BC), CEACAM1 shifts from an apical to a uniform membranous/cytoplasmic pattern, or is lost, as tumors dedifferentiate, inversely tracking the Ki‐67 proliferative index. In MCF‐7 cells, only CEACAM1‐4L suppresses proliferation, repressing cell cycle and growth factor genes.
Mykola Lyndin +3 more
wiley +1 more source