Results 31 to 40 of about 471,024 (280)

ClimbAR - An Arkansas Rock Climbing Documentary [PDF]

open access: yes, 2017
The goal of this thesis project, ‘ClimbAR’ - a rock climbing documentary - is to tell the story of a fringe sport/outdoor activity in the state of Arkansas.
Henkel, Daniel Alan
core   +2 more sources

Coordination in climbing: effect of skill, practice and constraints manipulation [PDF]

open access: yes, 2014
BACKGROUND: Climbing is a physical activity and sport involving many subdisciplines. Minimization of prolonged pauses, use of a relatively simple path through a route and smooth transitions between movements broadly define skilled coordination in ...
Brunetto, Yvonne   +4 more
core   +1 more source

Enteropathogenic E. coli shows delayed attachment and host response in human jejunum organoid‐derived monolayers compared to HeLa cells

open access: yesFEBS Letters, EarlyView.
Enteropathogenic E. coli (EPEC) infects the human intestinal epithelium, resulting in severe illness and diarrhoea. In this study, we compared the infection of cancer‐derived cell lines with human organoid‐derived models of the small intestine. We observed a delayed in attachment, inflammation and cell death on primary cells, indicating that host ...
Mastura Neyazi   +5 more
wiley   +1 more source

« Plus rien à prouver » : marche, course, escalade extrêmes

open access: yesRevue Italienne d'Etudes Françaises, 2021
Our research falls within the sphere of the linguistic disciplines, and in particular of the discourse analysis of the French school, privileging lexical data and phrasal items in the corpus we have compiled.
Mariagrazia Margarito
doaj   +1 more source

Nudged-elastic band method with two climbing images: finding transition states in complex energy landscapes [PDF]

open access: yes, 2014
The nudged-elastic band (NEB) method is modified with concomitant two climbing images (C2-NEB) to find a transition state (TS) in complex energy landscapes, such as those with serpentine minimal energy path (MEP).
Johnson, Duane   +3 more
core   +4 more sources

Plasmodium falciparum gametogenesis essential protein 1 (GEP1) is a transmission‐blocking target

open access: yesFEBS Letters, EarlyView.
This study shows Plasmodium falciparum GEP1 is vital for activating sexual stages of malarial parasites even independently of a mosquito factor. Knockout parasites completely fail gamete formation even when a phosphodiesterase inhibitor is added. Two single‐nucleotide polymorphisms (V241L and S263P) are found in 12%–20% of field samples.
Frederik Huppertz   +5 more
wiley   +1 more source

Paradise regained: older adult rock climbers turning space into place in the natural environment

open access: yesEnvigogika, 2015
At the time of writing there are over 10 million people aged over 65 living in the UK, and by 2050 the number is predicted to rise to 19 million. This expansion of the ageing population is mirrored worldwide, and over the past ten years has stimulated a ...
Mark Hickman   +2 more
doaj   +1 more source

Climbing down Gaussian peaks [PDF]

open access: yes, 2015
How likely is the high level of a continuous Gaussian random field on an Euclidean space to have a "hole" of a certain dimension and depth? Questions of this type are difficult, but in this paper we make progress on questions shedding new light in ...
Adler, Robert, Samorodnitsky, Gennady
core  

A Cre‐dependent lentiviral vector for neuron subtype‐specific expression of large proteins

open access: yesFEBS Letters, EarlyView.
We designed a versatile and modular lentivector comprising a Cre‐dependent switch and self‐cleaving 2A peptide and tested it for co‐expression of GFP and a 2.8 kb gene of interest (GOI) in mouse cortical parvalbumin (PV+) interneurons and midbrain dopamine (TH+) neurons.
Weixuan Xue   +6 more
wiley   +1 more source

Exaptation and emergence as mechanisms to cross fitness valleys during evolution: an example using simulated homing behaviour [PDF]

open access: yes, 2008
Evolution is often considered a gradual hill climbing process, slowly increasing the fitness of organisms. I investigate the evolution of homing behaviour in simulated intertidal limpets.
Richard Stafford
core   +1 more source

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