Results 41 to 50 of about 12,438,664 (296)

Deep Sequencing of FLT3‐ITD Enables Response Evaluation and Post‐Treatment Monitoring in Childhood AML: An Exploratory Study

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background An internal tandem duplication in the gene encoding Fms‐like tyrosine kinase 3 (FLT3‐ITD) is associated with high relapse risk and poor prognosis in acute myeloid leukemia (AML) and plays a crucial role in treatment decisions. Measurable residual disease (MRD) analysis of FLT3‐ITD during and after treatment has shown prognostic ...
Sofie Johansson Alm, Bea Tornberg, Erik Delsing Malmberg, Henrik Hasle, Kristian Løvvik Juul‐Dam, Lars Palmqvist, Borhan R. Saeed, Giti Shah Barkhordar, Anastasia Soboli, Anna Staffas, Jonas Abrahamsson, Linda Fogelstrand   +11 more
wiley   +1 more source

Competences of Clinical Psychologists

, 2019
Background: Politicians, societies, stakeholders, health care systems, patients, their relatives, their employers, and the general population need to know what they can expect from clinical psychologists.
ACLIPT Task Force On "Competences of Clinical Psychologists", EACLIPT Task Force On “Competences of Clinical Psychologists”, EACLIPT Task Force On "Competences of Clinical Psychologists",   +2 more
core   +1 more source

The birth and development of clinical physiology in Finland [PDF]

, 2022
The specialty of clinical physiology was established in Finland about 20 years later than in Sweden. In the early 1960s, six physicians working mainly in preclinical departments of physiology were certified as specialists in clinical physiology.
Turjanmaa Väinö, Hartiala Jaakko, Sovijärvi Anssi, Malmberg Pekka, Laitinen Tomi   +4 more
core   +1 more source

Claudin‐6 Protein Expression in Atypical Teratoid/Rhabdoid Tumors Is Strongly Enriched in the Molecular Subgroup AT/RT‐TYR

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Claudin‐6 has emerged as a promising immunotherapeutic target, yet protein‐level data in atypical teratoid/rhabdoid tumors (AT/RTs) have been inconsistent. We analyzed 36 well‐characterized AT/RT samples and found membranous claudin‐6 protein expression in 58% of cases, with striking enrichment in the molecular subgroup AT/RT‐TYR (100%) and ...
Victoria E. Fincke, Christian Thomas, Michael C. Frühwald, Pascal D. Johann, Martin Hasselblatt   +4 more
wiley   +1 more source

Time Toxicity in Wilms Tumor: Quantifying the Burden of Healthcare Interaction in the First Year After Diagnosis

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Wilms tumor (WT) treatment imposes a significant time burden on patients and their families. Time toxicity is a patient‐centered metric that quantifies the burden of healthcare interaction. We sought to define time toxicity in the first year after diagnosis of WT and hypothesized that it would increase as tumor stage and treatment ...
Caleb Q. Ashbrook, Veerain Gupta, Nicholas J. Clark, Vijay Rings, Lauren E. Corona, Douglass B. Clayton, Daniel J. Benedetti   +6 more
wiley   +1 more source

Bariatric Surgery in Clinical Practice

, 2022
obesity; disease; bariatric surgery; clinical ...

core   +1 more source

Heterogeneity in the Global Practice of Central Nervous System Staging in Pediatric Acute Lymphoblastic Leukemia

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Central nervous system (CNS) involvement in childhood acute lymphoblastic leukemia (ALL) is assessed by cell counting and cytomorphology from cerebrospinal fluid (CSF) and is used for treatment stratification worldwide. The ratio of “CNS2” patients in clinical trials ranges from 3% to 40%, with unclear prognostic significance ...
Laura Almási, Bernadett Borbála Huszti, Gábor Barna, Marko Kavcic, Janez Jazbec, Lennart Lenk, Vera Münch, Sophia Polychronopoulou, Ágnes Márk, Maria Thastrup, Lüder H. Meyer, Kjeld Schmiegelow, Cornelia Eckert, Christina Halsey, Dániel J. Erdélyi   +14 more
wiley   +1 more source

Are Hospital Pharmacists Ready for Precision Medicine in Nigerian Healthcare? Insights From a Multi‐Center Study

Health Care Science
Background Precision medicine (PM) has taken center stage in healthcare since the completion of the genomic project. Developed countries have gradually integrated PM into mainstream patient management. However, Nigeria still grapples with wide acceptance,
Goodness C. Nwokebu, Shadrach C. Eze, Prince J. Meziem, Catherine C. Eleje, Emmanuel I. Ugwu, Manuella O. Dagogo‐George, Favour O. Orisakwe, Gerald O. Ozota, Abdulmuminu Isah   +8 more
doaj   +1 more source

Clinical Pharmacogenetics Implementation Consortium (CPIC) Guideline for Dihydropyrimidine Dehydrogenase Genotype and Fluoropyrimidine Dosing: 2017 Update

, 2017
The purpose of this guideline is to provide information for the interpretation of clinical dihydropyrimidine dehydrogenase (DPYD) genotype tests so that the results can be used to guide dosing of fluoropyrimidines (5-fluorouracil and capecitabine ...
Schellens, Jan H M, Swen, Jesse J, Klein, T.E., Julia Barbarino, Kelly E. Caudle, Diasio, R.B., Caudle, K.E., Steven M. Offer, Amstutz, U., Schwab, M., Afd Pharmacoepi & Clinical Pharmacology, Barbarino, J., Schellens, J.H.M., Schwab, Matthias, Pharmacoepidemiology and Clinical Pharmacology, Linda M. Henricks, McLeod, H.L., Offer, S.M., Amstutz, Ursula, Swen, Jesse J., Jesse J. Swen, Henricks, L.M., Jan H.M. Schellens, Caudle, Kelly E, Klein, Teri E, Matthias Schwab, Barbarino, Julia, Henricks, Linda M, Robert B. Diasio, Swen, J.J., McLeod, Howard L, Howard L. McLeod, Offer, Steven M, Ursula Amstutz, Teri E. Klein, Diasio, Robert B   +35 more
core   +1 more source

Clinical Exercise Physiology Accreditation: An Audit of Existing Standards

, 2023
Background: Health professions such as clinical exercise physiology are founded on a set of standards that outline base level knowledge, skills, and competencies to define the roles and scope of practice of the profession.
Nathan E. Reeves, Carly Ryan, Ryan, Carly, Davison, Kade, Kade Davison, Reeves, Nathan E   +5 more
core   +1 more source