Results 61 to 70 of about 14,145,704 (295)

Clinical pharmacology of novel anticancer agents: bioanalysis - clinical pharmacokinetics - mass balance studies [PDF]

, 2016
Cancer is already among the leading causes of death worldwide and the number of new cases is expected to rise by about 70% over the next two decades. Even though the number of new cases will rise, the survival rates are also increasing due to earlier ...
Pharmacoepidemiology and Clinical Pharmacology, Nijenhuis, Cynthia M   +1 more
core  

Clinical Pharmacogenetics Implementation Consortium (CPIC) Guideline for Dihydropyrimidine Dehydrogenase Genotype and Fluoropyrimidine Dosing: 2017 Update [PDF]

, 2017
The purpose of this guideline is to provide information for the interpretation of clinical dihydropyrimidine dehydrogenase (DPYD) genotype tests so that the results can be used to guide dosing of fluoropyrimidines (5-fluorouracil and capecitabine ...
Schellens, Jan H M, Swen, Jesse J, Klein, T.E., Julia Barbarino, Kelly E. Caudle, Diasio, R.B., Caudle, K.E., Steven M. Offer, Amstutz, U., Schwab, M., Afd Pharmacoepi & Clinical Pharmacology, Barbarino, J., Schellens, J.H.M., Schwab, Matthias, Pharmacoepidemiology and Clinical Pharmacology, Linda M. Henricks, McLeod, H.L., Offer, S.M., Amstutz, Ursula, Swen, Jesse J., Jesse J. Swen, Henricks, L.M., Jan H.M. Schellens, Caudle, Kelly E, Klein, Teri E, Matthias Schwab, Barbarino, Julia, Henricks, Linda M, Robert B. Diasio, Swen, J.J., McLeod, Howard L, Howard L. McLeod, Offer, Steven M, Ursula Amstutz, Teri E. Klein, Diasio, Robert B   +35 more
core   +3 more sources

Very long-chain acyl-CoA dehydrogenase deficiency revisited: a retrospective genotype–phenotype analysis in a Saudi tertiary center

Frontiers in Genetics
IntroductionIn this retrospective study, we analyzed clinical, biochemical, and genetic data and examined correlations between prevalent variants and outcomes of very long-chain acyl-CoA dehydrogenase (VLCAD) deficiency.MethodsPatients with VLCAD ...
Suzan Suliman Alhumaidi, Fahad Abdulrahman Algaeed, Meshari Fayez Aladhadh, Sara Abdulrahman Alkaff   +3 more
doaj   +1 more source

Language, Culture, and Cancer: Qualitative Insights Into Communication Disparities Among Spanish‐Speaking Caregivers of Children With Cancer

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Latino children are projected to make up nearly one‐third of United States (US) children by 2060, and many of their caregivers speak Spanish. Prior survey research has documented communication difficulties for Spanish‐speaking caregivers of children with cancer, but contemporary qualitative data are limited.
Jenny Ruiz, Alejandra Curbelo‐Paz, Sonia Morales, Elizabeth Contreras, Amy Houtrow, Scott H. Maurer, Judy C. Chang   +6 more
wiley   +1 more source

Diagnosis and staging of patients with ovarian cancer: National Clinical Guideline No. 20 Annex 1: Systematic review of cost effectiveness

, 2018
The purpose of this systematic review was to identify and evaluate economic evidence to inform the clinical recommendations of this NCG. Review of the cost-effectiveness of health technologies enables guideline developers to explicitly consider how ...
HRB-CICER (Collaboration in Ireland for Clinical Effectiveness Reviews)
core  

Stop Smoking: National Clinical Guideline No. 28

, 2022
This National Clinical Guideline has been developed by the Stop Smoking Guideline Development Group (GDG), within the Tobacco Free Ireland Programme, Strategy & Research, Healthcare Strategy, Health Service Executive (HSE).
Department of Health (DoH), National Clinical Effectiveness Committee (NCEC)   +1 more
core  

Clinical Trials and Clinical Judgment

Journal of the American College of Cardiology, 2008
![Figure][1] Cardiovascular specialists have become justifiably proud of their commitment to evidence-based medicine and clinical trials. More large-scale randomized prospective clinical trials (RCTs) are performed in cardiology than in any other field, and contemporary practice is ...
openaire   +2 more sources

Biphasic Clinical Course of Pediatric Cytomegalovirus‐Associated Immune Thrombocytopenia: Early Poor Treatment Response but Favorable Long‐Term Outcomes

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Cytomegalovirus (CMV) is a recognized trigger of immune thrombocytopenia (ITP); however, its incidence and impact on disease course in children remain controversial. Therefore, we aimed to characterize the clinical course of pediatric patients with CMV‐associated ITP.
Oded Gilad, Ohad Atia, Osama Tanous, Dafna Brik Simon, Michal Dvori, Miriam Cohen, Tracie A. Goldberg, Efraim Bilavsky, Joanne Yacobovich, Orna Steinberg‐Shemer   +9 more
wiley   +1 more source

The Pharmacological Management of Cancer Pain in Adults Clinical Audit Tool

, 2016
The audit standards are based on the Pharmacological Management of Cancer Pain in Adults NCEC National Clinical Guideline No. 9. In developing this tool consideration has been given to the clinical issues covered by the guideline and the potential ...
National Clinical Programme for Palliative Care
core  

A conversation with Alan T. Tita, MD, PhD, Associate Dean, Global and Women’s Health, University of Alabama at Birmingham Heersink School of Medicine

Journal of Clinical and Translational Science, 2023
Clinical Research Forum
doaj   +1 more source