Results 11 to 20 of about 14,985,887 (194)
IL-11 Is Elevated and Drives the Profibrotic Phenotype Transition of Orbital Fibroblasts in Thyroid-Associated Ophthalmopathy
Frontiers in Endocrinology, 2022 Orbital fibrosis is a hallmark of tissue remodeling in thyroid-associated ophthalmopathy (TAO). Previous studies have shown that interleukin (IL)-11 plays a pivotal profibrotic role in various inflammatory and autoimmune diseases. However, the expression Pengsen Wu, Bingying Lin, Siyu Huang, Jie Meng, Fan Zhang, Min Zhou, Xiangqing Hei, Yu Ke, Huasheng Yang, Danping Huang +9 moredoaj +1 more sourceFeasibility of Conducting Comparative Effectiveness Research and Validation of a Clinical Disease Activity Score for Chronic Nonbacterial Osteomyelitis
Journal of Rheumatology, 2022 Objective Prospective comparative effectiveness research (CER) in chronic nonbacterial osteomyelitis (CNO) is lacking. Our objectives were to (1) determine the use and safety of each consensus treatment plan (CTP) regimen for CNO, (2) assess the ...Eveline Y. Wu, M. Oliver, Joshua Scheck, S. Lapidus, U. Akca, S. Yasin, S. Stern, A. Insalaco, M. Pardeo, G. Simonini, E. Marrani, Xing Wang, Bin Huang, Leonard K. Kovalick, Natalie Rosenwasser, G. Casselman, A. Liau, Yurong Shao, Claire C. Yang, D. M. Mosa, Lori B. Tucker, H. Girschick, R. Laxer, J. Akikusa, C. Hedrich, K. Onel, F. Dedeoğlu, M. Twilt, P. Ferguson, S. Ozen, Yongdong Zhao +30 moresemanticscholar +1 more sourceValidation of a score tool for measurement of histological severity in juvenile dermatomyositis and association with clinical severity of disease. [PDF]
, 2013 OBJECTIVES: To study muscle biopsy tissue from patients with juvenile dermatomyositis (JDM) in order to test the reliability of a score tool designed to quantify the severity of histological abnormalities when applied to biceps humeri in addition to ...Pilkington, Clarissa A, Varsani, Hemlata, Marie, Suely KN, Lundberg, Ingrid E, Sallum, Adriana M E, Banwell, Brenda, Sallum, Adriana ME, Corse, Andrea M, Charman, Susan C, Jacques, Thomas S, Amato, Anthony A, Bove, Kevin E, Emslie-Smith, Alison M, Marie, Suely K N, Holton, Janice L, Nennesmo, Inger, Rushing, Elisabeth J, UK Juvenile Dermatomyositis Research Group, Li, Charles K, Amato, Anthony, Minetti, Carlo, Sewry, Caroline, Wedderburn, Lucy R, Bove, KE, Banwell, B, Varsani, H, Emslie-Smith, AM, Marie, SKN, Corse, AM, Li, CK, Jacques, TS, Amato, AA, Charman, SC +32 morecore +1 more sourceUse of the painDETECT tool in rheumatoid arthritis suggests neuropathic and sensitization components in pain reporting. [PDF]
, 2014 Rheumatoid arthritis (RA) is an inflammatory autoimmune condition typified by systemic inflammation targeted toward synovial joints. Inhibition of proinflammatory networks by disease-modifying antirheumatic drugs, eg, methotrexate and biologic therapies, Sofat, N, Magan, T, Vargas, M, Ahmed, S, Harrison, A +4 morecore +1 more sourceReliability of Histologic Assessment for NAFLD and Development of an Expanded NAFLD Activity Score
Hepatology, 2022 The NASH Clinical Research Network histologic scoring system, the gold‐standard NASH histology assessment for clinical trials, has demonstrated intrarater and interrater variability.R. Pai, V. Jairath, M. Hogan, G. Zou, O. Adeyi, Q. Anstee, B. Aqel, C. Behling, Elizabeth J. Carey, A. Clouston, K. Corey, B. Feagan, D. Kleiner, Christopher Ma, S. McFarlane, M. Noureddin, V. Ratziu, Mark A. Valasek, Z. Younossi, S. Harrison, R. Loomba +20 moresemanticscholar +1 more sourceAmerican College of Rheumatology/European League Against Rheumatism Provisional Definition of Remission in Rheumatoid Arthritis for Clinical Trials [PDF]
, 2011 Remission in rheumatoid arthritis (RA) is an increasingly attainable goal, but there is no widely used definition of remission that is stringent but achievable and could be applied uniformly as an outcome measure in clinical trials.Matucci-Cerinic, M., Richards, P., American College of Rheumatology,, Robert Landewé, Pamela Richards, Alan Tyndall, Wit, M. de, Siegel, Jeffrey N., John Kirwan, Gillian Hawker, Daniel Aletaha, Simon, L.S., Dougados, Maxime, White, Barbara, Montie, Pamela, Kvien, T.K., Andrew Brown, Funovits, J., Combe, Bernard, Aletaha, Daniel, Tuyl, H.D. van, Tuulikki Sokka, Brooks, Peter, Brown, Andrew, Kirwan, J, Josef S. Smolen, Bathon, J., Suzan Verstappen, Choi, Hyon, Allaart, Cornelia F, Furst, Daniel E., Kaleb Michaud, Heijde, D. van der, van der Heijde, D., George Wells, Cornelia F Allaart, Furst, D., Landewe, R., Josef S Smolen, Brooks, Peter M., Allaart, Cornelia F., Sokka, Tuulikki, Maarten de Wit, David T. Felson, Peter Brooks, Verstappen, Suzan, Boers, M., Choi, H., Khanna, Dinesh, Khanna, D., Aletaha, D., Strand, Vibeke, Bombardieri, Stefano, Kvien, Tore K., Wolfe, F, Boers, Maarten, Stefano Bombardieri, Listing, J., Tugwell, P, Zhang, B., Joan Bathon, Lee S. Simon, Barbara White, Richards, Pamela, Wolfe, Frederick, Sokka, T., Maxime Dougados, Angela Zink, van Tuyl, Lilian H. D., van Tuyl, H.D., Hawker, G., Brown, A., Felson, David T., Paul Emery, Keystone, E., Bathon, Joan, Listing, Joachim, Verstappen, S., Zink, Angela, Combe, B., Michaud, K., Hyon Choi, Wolfe, F., Daniel Furst, Joachim Listing, Funovits, Julia, Gomez-Reino, J., de Wit, Maarten P. T., Emery, Paul, Gomez-Reino, Juan, Wells, George, Jeffrey N Siegel, Lilian H D van Tuyl, Theodore Pincus, Zink, A., Michaud, Kaleb, Marco Matucci-Cerinic, Tyndall, A., Lee S Simon, Keystone, Edward, European League Against Rheumatism,, Landewé, Robert, Emery, P., Julia Funovits, Zhang, Bi, Jeffrey N. Siegel, Maarten Boers, Van Tuyl, Lilian H D, de Wit, Maarten, Pincus, T., Hawker, Gillian, Strand, V., Edward Keystone, Frederick Wolfe, Martin-Mola, E., Pamela Montie, de Wit, M., van Tuyl, L.H.D., Tore K. Kvien, Cornelia F. Allaart, Emilio Martin-Mola, Matucci-Cerinic, Marco, Emery, P, Zhang, Bin, Tyndall, Alan, Bernard Combe, Dougados, M., Kirwan, J., David T Felson, Tugwell, Peter, Allaart, C.F., Brown, A, Juan Gomez-Reino, Vibeke Strand, Tuyl, L.H.D. van, Montie, P., Brooks, P., Peter Tugwell, Kirwan, John, Simon, Lee S., Furst, Daniel, Bombardieri, S., van der Heijde, Desirée, Dinesh Khanna, White, B., Pincus, Theodore, Wells, G., Siegel, J.N., Martin-Mola, Emilio, Tugwell, P., Felson, D.T., Desirée van der Heijde, Smolen, Josef S., Lilian H. D. van Tuyl, Smolen, J.S., Strand, V, Bin Zhang +156 morecore +2 more sourcesDevelopment of the Cold Urticaria Activity Score
, 2022 25092519Background: Cold urticaria (ColdU) is a form of inducible urticaria where cold induces wheals and/or angioedema. The burden of disease is high and linked to trigger thresholds, exposure, and avoidance.Dorothea Terhorst‐Molawi, Weller, Karsten, Altunergil, Tatjana, Tatjana Altunergil, Marcus Maurer, Brockstaedt, Maxi, Ahsan, Dalia Melina, Bernstein, J.A., Karsten Weller, Annika Gutsche, Jonathan A. Bernstein, Gutsche, Annika, Maurer, Marcus, Dalia Melina Ahsan, Altrichter, Sabine, Sabine Altrichter, Terhorst-Molawi, Dorothea, Maxi Brockstaedt +17 morecore +1 more sourceDefinition and Validation of the American College of Rheumatology 2021 Juvenile Arthritis Disease Activity Score Cutoffs for Disease Activity States in Juvenile Idiopathic Arthritis
Arthritis & Rheumatology, 2021 To develop and validate new Juvenile Arthritis Disease Activity Score 10 (JADAS10) and clinical JADAS10 (cJADAS10) cutoffs to separate the states of inactive disease (ID), minimal disease activity (MiDA), moderate disease activity (MoDA), and high ...C. Trincianti, Evert Hendrik Pieter Van Dijkhuizen, A. Alongi, M. Mazzoni, J. Swart, I. Nikishina, P. Lahdenne, L. Rutkowska-Sak, T. Avčin, P. Quartier, V. Panavienė, Y. Uziel, C. Pruunsild, V. Vargova, S. Vilaiyuk, P. Doležalová, S. Ringold, M. Garrone, N. Ruperto, A. Ravelli, A. Consolaro +20 moresemanticscholar +1 more source
