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Teprotumumab for Thyroid-Associated Ophthalmopathy [PDF]
New England Journal of Medicine, 2017 BACKGROUND: Thyroid-associated ophthalmopathy, a condition commonly associated with Graves’ disease, remains inadequately treated. Current medical therapies, which primarily consist of glucocorticoids, have limited efficacy and present safety concerns ...
Terry J Smith +2 more
exaly +8 more sources
Presence of thyroid-associated ophthalmopathy in Hashimoto’s thyroiditis [PDF]
International Journal of Ophthalmology, 2014 AIM:To determine the prevalence of ophthalmopathy in Hashimoto’s patients and to make a comparison in subgroups of patientsMETHODS:The study involved 110 Hashimoto’s thyroiditis patients and 50 control subjects attending to the endocrinology department ...
Emrah Kan +3 more
doaj +5 more sources
Thyroid-Associated Ophthalmopathy in a Hypothyroid Patient [PDF]
Acta Clinica CroaticaThyroid-associated ophthalmopathy (TAO) is an autoimmune disorder of the orbit that occurs predominantly in Grave’s hyperthyroidism, while it is an uncommon clinical finding in patients with Hashimoto’s thyroiditis (HT) and hypothyroidism.
Dorotea Filipan +4 more
doaj +4 more sources
Advances in artificial intelligence in thyroid-associated ophthalmopathy [PDF]
Frontiers in EndocrinologyThyroid-associated ophthalmopathy (TAO), also referred to as Graves’ ophthalmopathy, is a medical condition wherein ocular complications arise due to autoimmune thyroid illness.
Jing Rao, Guiqin Liu, Weihua Yang
exaly +4 more sources
Cytokines in Thyroid-Associated Ophthalmopathy
Journal of Immunology Research, 2022 Thyroid-associated ophthalmopathy (TAO), also known as thyroid eye disease (TED) or Graves’ orbitopathy (GO), is a complex autoimmune condition causing visual impairment, disfigurement, and harm to patients’ physical and mental health.
Pengbo Zhang, Huang Zhu
doaj +4 more sources
Thyroid-associated ophthalmopathy: the role of oxidative stress [PDF]
Frontiers in EndocrinologyThyroid-associated ophthalmopathy (TAO) is an autoimmune condition affecting the eyes, characterized by proptosis, extraocular muscle involvement, and in severe cases, vision impairment including diplopia, optic neuropathy, and potential blindness.
Haoyu Li
exaly +4 more sources
Thyroid-associated Ophthalmopathy
Türk Oftalmoloji Dergisi, 2017 Thyroid-associated ophthalmopathy is the most frequent extrathyroidal involvement of Graves’ disease but it sometimes occurs in euthyroid or hypothyroid patients.
Esra Şahlı, Kaan Gündüz
doaj +3 more sources
Glymphatic System Dysfunction in Thyroid-Associated Ophthalmopathy: A Multimodal MRI Study. [PDF]
CNS Neurosci TherTAO patients exhibit impaired glymphatic function, with reduced DTI‐ALPS indices and gBOLD‐CSF coupling, but unchanged choroid plexus volume. These alterations correlate with neuropsychological symptoms and sleep disturbances. Restoring glymphatic activity may offer a therapeutic approach to enhance patient outcomes.
Zhang L, Yao J, Qi Y, Luo Y, Liu J.
europepmc +2 more sources
Clinical application of cone beam CT in intensity-modulated radiotherapy for the moderate to severe thyroid-associated ophthalmopathy. [PDF]
J Appl Clin Med PhysAbstract Background Cone beam CT (CBCT) has been reported for intensity‐modulated radiation therapy (IMRT) of various cancers due to its real‐time imaging capabilities, but studies on its application in orbital diseases, particularly moderate to severe thyroid‐associated ophthalmopathy (TAO), remain limited.
Kang D, Hu H, Ma S, Bin S.
europepmc +2 more sources
Glycosaminoglycans in Thyroid-Associated Ophthalmopathy
Autoimmunity, 1992 Glycosaminoglycan (GAG) accumulation in the retrobulbar space of patients with thyroid-associated ophthalmopathy (TAO) has been documented in a number of immunohistochemical studies. In order to gain further insight into possible immunopathogenic mechanisms, the influence of humoral immunity on retrobulbar fibroblasts (RF) as GAG producing cells as ...
G Kahaly, C Stover
exaly +4 more sources