Context: Considerable evidence of gender, ethnicity, thyroid dysfunction, and environmental factors including smoking influencing the development and progression of thyroid eye disease (TED).
Dhakshini L Subramaniam +2 more
doaj +1 more source
Antagonistic Autoantibodies to Insulin-Like Growth Factor-1 Receptor Associate with Poor Physical Strength [PDF]
Natural autoantibodies to the IGF1 receptor (IGF1R-aAb) have been described in relation to Graves' ophthalmopathy. Other physiological roles of natural IGF1R-aAb are not known. We hypothesized that IGF1R-aAb may be related to muscle development.
Becker, Niels-Peter +7 more
core +1 more source
Thyroid Associated Ophthalmopathy
Thyroid-related immune orbitopathy (TRIO) has a variety of names previously, such as Graves’ ophthalmopathy, ophthalmic Graves’ disease, and thyroid-associated ocular disease. Although their names are different, their clinical characteristics are the same, that is, abnormal thyroid endocrine axis (endocrine hormones secreted by the thyroid, pituitary ...
Jianmin Ma, Yun Feng
+6 more sources
Extraocular muscle sampled volume in Graves' orbitopathy using 3-T fast spin-echo MRI with iterative decomposition of water and fat sequences [PDF]
Background: Current magnetic resonance imaging (MRI) techniques for measuring extraocular muscle (EOM) volume enlargement are not ideally suited for routine follow-up of Graves’ ophthalmopathy (GO) because the difficulty of segmenting the muscles at ...
BRUSCOLINI, ALICE +4 more
core +1 more source
Antigen receptor variable region repertoires expressed by T cells infiltrating thyroid, retroorbital, and pretibial tissue in Graves' disease [PDF]
To date, it has remained unclear whether T cells infiltrating thyroid, retroorbital, and pretibial tissue of patients with Graves' ophthalmopathy and pretibial dermopathy represent a primary immune response that is directed against certain antigenic ...
Heufelder, Armin E. +2 more
core +1 more source
A Genomic Point Mutation in the Extracellular Domain of the Thyrotropin Receptor in Patients with Graves’ Ophthalmopathy [PDF]
Orbital and pretibial fibroblasts are targets of autoimmune attack in Graves' ophthalmopathy (GO) and pretibial dermopathy (PTD). The fibroblast autoantigen involved in these peripheral manifestations of Graves' disease and the reason for the association
Bahn, Rebecca S. +3 more
core +1 more source
Oftalmopatía tiroidea: determinación de parámetros de actividad clínica de la oftalmopatía tiroidea como factor pronóstico de respuesta al tratamiento inmunosupresor [PDF]
Objective: To determine the usefulness of the clinical, biochemical and thyroid imaging parameters in patients with thyroid-associated ophthalmopathy, in predicting their response to immunosuppressive treatment.
Belzunce, A. (Arnaldo) +4 more
core +1 more source
Thyroid-associated ophthalmopathy (TAO) is a well-known and frequent epiphenomenon of a hyperthyroid autoimmune disease that can present with proptosis, strabismus, and diplopia.
Nicola Cavasin +3 more
doaj +1 more source
The significance of ophthalmological features in diagnosis of thyroid-associated ophthalmopathy
Background Thyroid-associated ophthalmopathy (TAO) is an autoimmune disorder. It has discriminable appearance. This study was conducted to dig the clinical significance of demographic characteristics and ophthalmologic diagram features in TAO diagnosis ...
Xiao Huang +11 more
doaj +1 more source
Epigenetics effect on pathogenesis of thyroid-associated ophthalmopathy [PDF]
Thyroid-associated ophthalmopathy (TAO) is an autoimmune disease. Recent studies have found the aberrant epigenetics in TAO, including DNA methylation, non-coding RNAs, and histone modification.
Jia-Min Cao +4 more
doaj +1 more source

