Results 1 to 10 of about 13,315 (221)
New England Journal of Medicine, 2010 Graves' orbitopathy is part of an autoimmune systemic disease which compiles hyperthyroidism, orbitopathy, dermopathy and acropachy. Stimulating antibodies against the TSH receptor play the central pathogenetic role. Main symptoms of Graves' orbitopathy comprise soft tissue inflammation, proptosis impairment of ocular motility and lid retraction ...
A, Eckstein, J, Esser
exaly +7 more sources
Immunomodulators in Graves’ ophthalmopathy: a systematic review [PDF]
Frontiers in EndocrinologyBackgroundGraves’ Ophthalmopathy (GO), or thyroid eye disease, is an extrathyroidal complication of Graves’ disease, causing a significant impact on patients’ quality of life. There are consensus statements from both the American Thyroid Association (ATA)
Antoinette Yeung +10 more
doaj +2 more sources
Insulin-Like Growth Factor Pathway and the Thyroid
Frontiers in Endocrinology, 2021 The insulin-like growth factor (IGF) pathway comprises two activating ligands (IGF-I and IGF-II), two cell-surface receptors (IGF-IR and IGF-IIR), six IGF binding proteins (IGFBP) and nine IGFBP related proteins.
Terry J. Smith
doaj +1 more source
Thyroid eye disease or Graves’ orbitopathy: What name to use, and why it matters
Frontiers in Endocrinology, 2022 There is currently no universally accepted name for inflammatory disease of the eye and orbit associated with thyroid autoimmune disease. Variability in terminology impedes the evaluation of scientific literature and clinical collaboration and can affect
Lilly H. Wagner +5 more
doaj +1 more source
Extraction (DSX) from Erigeron breviscapus modulates outward potassium currents in rat retinal ganglion cells [PDF]
International Journal of Ophthalmology, 2015 AIM: To investigate the effect of DSX, an active component extracted from Erigeron breviscapus, on the voltage-gated outward K+ channel currents in rat retinal ganglion cells (RGCs) by using electrophysiological method, and to explore the possible ...
Shuo Yin +4 more
doaj +1 more source
Taiwan Journal of Ophthalmology, 2023 Thyroid eye disease (TED) is characterized by progressive orbital inflammation. In severe cases, it can lead to dysthyroid optic neuropathy (DON), involving death of retinal ganglion cells and permanent vision loss.
Lillian Chien +3 more
doaj +1 more source
Application of Proteomics Analysis and Animal Models in Optic Nerve Injury Diseases
Brain Sciences, 2023 Optic nerve damage is a common cause of blindness. Optic nerve injury is often accompanied by fundus vascular disease, retinal ganglion cell apoptosis, and changes in retinal thickness.
Zhaoyang Meng +4 more
doaj +1 more source
Overview of Graves Ophthalmopathy Literature From 1999 to 2019: Bibliometric Analysis
Interactive Journal of Medical Research, 2021 BackgroundResearch on Graves ophthalmopathy has increased remarkably over the last 2 decades; however, few statistical analyses of the data presented in these publications have been conducted.
Jiamin Cao +5 more
doaj +1 more source
Thyroid-related ophthalmopathy development in concurrence with growth hormone administration
BMC Endocrine Disorders, 2021 Background Thyroid stimulating hormone (TSH) receptor and local infiltrate lymphocytes have been considered as major pathological factors for developing thyroid-related ophthalmopathy.
Shimpei Iwata +13 more
doaj +1 more source
Altered functional connectivity of primary visual cortex in adults with strabismus and amblyopia: a resting-state fMRI study [PDF]
Journal of Integrative Neuroscience, 2022 Functional connectivity of the primary visual cortex was explored with resting functional magnetic resonance imaging among adults with strabismus and amblyopia and healthy controls.
Li-Qi Liu +8 more
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