Quantitative MRI Assessment of Orbital Structures in Radioactive Iodine-131 Therapy for Inactive Graves' Ophthalmopathy. [PDF]
Objective The understanding regarding the role of orbital magnetic resonance imaging (MRI) in predicting the prognosis of radioactive iodine‐131 (I‐131) therapy for patients with inactive Graves’ ophthalmopathy (GO) is limited. Therefore, this study aimed to explore the application of MRI quantitative measurements of orbital structures in radioactive I‐
Wang M, Shen ZY, Wu XW.
europepmc +2 more sources
Immunomodulators in Graves’ ophthalmopathy: a systematic review [PDF]
BackgroundGraves’ Ophthalmopathy (GO), or thyroid eye disease, is an extrathyroidal complication of Graves’ disease, causing a significant impact on patients’ quality of life. There are consensus statements from both the American Thyroid Association (ATA)
Antoinette Yeung +10 more
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Clinical application of cone beam CT in intensity-modulated radiotherapy for the moderate to severe thyroid-associated ophthalmopathy. [PDF]
Abstract Background Cone beam CT (CBCT) has been reported for intensity‐modulated radiation therapy (IMRT) of various cancers due to its real‐time imaging capabilities, but studies on its application in orbital diseases, particularly moderate to severe thyroid‐associated ophthalmopathy (TAO), remain limited.
Kang D, Hu H, Ma S, Bin S.
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The Diagnostic Value of Mean Apparent Propagator-MRI in Dysthyroid Optic Neuropathy: A Quantitative Analysis of the Entire Visual Pathway. [PDF]
The diagnostic model combining orbital and intracranial MAP‐MRI parameters could significantly optimize diagnostic efficiency of dysthyroid optic neuropathy. Comprehensive MAP‐MRI parameters analysis of the entire visual pathway enables a deeper understanding of disease involvement, provides novel insights into the early accurate diagnosis and ...
Zou M +7 more
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Insulin-Like Growth Factor Pathway and the Thyroid
The insulin-like growth factor (IGF) pathway comprises two activating ligands (IGF-I and IGF-II), two cell-surface receptors (IGF-IR and IGF-IIR), six IGF binding proteins (IGFBP) and nine IGFBP related proteins.
Terry J. Smith
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Thyroid eye disease or Graves’ orbitopathy: What name to use, and why it matters
There is currently no universally accepted name for inflammatory disease of the eye and orbit associated with thyroid autoimmune disease. Variability in terminology impedes the evaluation of scientific literature and clinical collaboration and can affect
Lilly H. Wagner +5 more
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Extraction (DSX) from Erigeron breviscapus modulates outward potassium currents in rat retinal ganglion cells [PDF]
AIM: To investigate the effect of DSX, an active component extracted from Erigeron breviscapus, on the voltage-gated outward K+ channel currents in rat retinal ganglion cells (RGCs) by using electrophysiological method, and to explore the possible ...
Shuo Yin +4 more
doaj +1 more source
Thyroid eye disease (TED) is characterized by progressive orbital inflammation. In severe cases, it can lead to dysthyroid optic neuropathy (DON), involving death of retinal ganglion cells and permanent vision loss.
Lillian Chien +3 more
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Application of Proteomics Analysis and Animal Models in Optic Nerve Injury Diseases
Optic nerve damage is a common cause of blindness. Optic nerve injury is often accompanied by fundus vascular disease, retinal ganglion cell apoptosis, and changes in retinal thickness.
Zhaoyang Meng +4 more
doaj +1 more source

