Results 41 to 50 of about 3,956 (171)

Therapeutic targets for fibro-inflammation in Graves’ orbitopathy

Taiwan Journal of Ophthalmology
Graves’ orbitopathy (GO), a complex autoimmune disorder, remains the most common extrathyroidal manifestation of Graves’ disease. Its pathogenesis is characterized by a progressive transition from inflammation to fibrosis, leading to debilitating ocular ...
Young Jae Kang, Jin Sook Yoon
doaj   +1 more source

Trends of Eye and Adnexa‐Related Hospital Admissions in Lebanon: An Epidemiological Retrospective Study

Health Science Reports, Volume 9, Issue 4, April 2026.
ABSTRACT Background and Aim Visual impairment represents a major public health concern, affecting millions of individuals worldwide. In recent years, the global burden of eye diseases and vision impairment has continued to grow. This study aims to investigate the trends in eye and adnexa‐related hospital admissions in Lebanon from 2006 to 2019, as ...
Dany Akiki, Riwa Ibrahim, Mohammad Al Zein, Mona Bou Khdoud, Maria Maalouf, Jamal Bleik   +5 more
wiley   +1 more source

Clinical Case of the Combined Course of Diffuse Toxic Goiter and Autoimmune Ophthalmopathy

Mìžnarodnij Endokrinologìčnij Žurnal, 2014
The article presents the experience of treating a patient with diffuse toxic goiter in conjunction with autoimmune ophthalmopathy, about what the patient took thyrostatic drugs, β-blockers, systemic glucocorticoids.
Ye.N. Martsinik, T.V. Chursinova, V.N. Serdyuk, L.N. Pastarus, T.L. Krainyak   +4 more
doaj   +1 more source

Modified Deep Lateral Wall Decompression Surgery in the Treatment of Thyroid‐Associated Ophthalmopathy: A Retrospective Evaluation

Eye &ENT Research, Volume 3, Issue 1, Page 5-10, March 2026.
ABSTRACT Background Thyroid‐associated ophthalmopathy (TAO) may lead to severe exophthalmos and dysthyroid optic neuropathy (DON), which can threaten visual function. Orbital decompression surgery is often required when medical therapy is insufficient; however, traditional deep lateral wall decompression techniques remain associated with several ...
Shuo Wu, Jiahong Lao, Rongrong Ge, Zhaohui Shi, Qintai Yang   +4 more
wiley   +1 more source

COVID-associated neuro-ophthalmopathy. Issues of diagnosis and treatment

, 2022
Since the beginning of the COVID-19 pandemic, a large number of reports on extrapulmonary manifestations of the disease have appeared, sometimes focusing on complex cases and challenging diagnostic tasks.
Nikita Yu. Shalkin, Elena V. Savchenko, Igor N. Stepanov, Marina R. Kovaleva   +3 more
core  

Practical Guidelines Management of Graves Ophthalmopathy [PDF]

, 2020
Graves’ ophthalmopathy is the most common extra-thyroid manifestation in patients with Graves’ disease, based on inflammatory and autoimmune conditions in orbital tissue.
Subekti, Imam, Harbuwono, Dante Saksono, Purnamasari, Dyah, Kodrat, Henry, Soebardi, Suharko, Sidik, M, Suharko, Hernawita, Gondhowiardjo, Soehartati, Siswoyo, Alvita Dewi, Wisnu, Wismandari, Wulani, Vally, Suroyo, Indrati, Tahapary, Dicky Levenus, Tarigan, Tri Juli Edi, Kurniawan, Farid, Suardana, Gusti G, Soewondo, Pradana, Darmowidjojo, Budiman, Nusanti, Syntia, Dewiputri, Salmarezka   +19 more
core   +1 more source

Management of Graves' ophthalmopathy

, 2007
Management of Graves' ophthalmopathy is preferably done in a multidisciplinary setting. Smoking is associated with worse disease outcome. (131)I therapy for hyperthyroidism can also worsen ophthalmopathy, especially if administered during active disease ...
Wiersinga, Wilmar M.
core   +1 more source

Total Thyroidectomy for the Treatment of Recurrent Graves' Disease With Ophthalmopathy

Asian Journal of Surgery, 2008
Objective: To determine the outcome of recurrent Graves’ disease with ophthalmopathy (GO) following bilateral total thyroidectomy (TT) in patients with no history of anti-inflammatory treatment with steroids or radioactive iodine treatment. Methods: From
Ahmet Nart, Adam Uslu, Ahmet Aykas, Fatih Yüzbaşoğlu, Murat Doğan, Özgür Demirtaş, Cenk Şimşek   +6 more
doaj   +1 more source

Retinal Capillary Density Reduction Contributes to Dysthyroid Optic Neuropathy via an L‐Arginine‐NO Pathway: A Metabonomics and Clinical Trial Study

MedComm, Volume 7, Issue 3, March 2026.
Oxidative stress induces endothelial nitric oxide synthase (eNOS) uncoupling and L‐arginine depletion, reducing nitric oxide (NO) bioavailability in vascular endothelium and contributing to decreased retinal capillary density (RCD) in dysthyroid optic neuropathy (DON).
Yunhai Tu, Congcong Yan, Lu Chen, Weijie Liu, Xiaozhou Hu, Mengyuan Gao, Wei Rao, Jiayi Zhang, Junye Zhu, Hui Wu, Kang Zhang, Meng Zhou, Wencan Wu   +12 more
wiley   +1 more source

Medical management of Graves' ophthalmopathy

, 1995
In most patients with Graves' hyperthyroidism the eye signs are self-limiting and mostly subclinical. However, about one-third of the patients have clinically relevant ophthalmopathy, which can be disabling and disfiguring.
Prummel, M. F., Wiersinga, W. M.
core   +1 more source