Results 51 to 60 of about 10,569 (220)
, 1999 OBJECTIVE The relationship between the method of treatment of hyperthyroidism due to Graves' disease and the course of Graves' ophthalmopathy is debated.
BARTALENA L. +9 more
core +2 more sources
Frontiers in PediatricsBackgroundOphthalmopathy occurring in childhood can easily lead to irreversible visual impairment, and therefore a great deal of clinical and fundamental researches have been conducted in pediatric ophthalmopathy.
Qianfang Jia +7 more
doaj +1 more source
CNS Neuroscience &Therapeutics, Volume 32, Issue 2, February 2026.The diagnostic model combining orbital and intracranial MAP‐MRI parameters could significantly optimize diagnostic efficiency of dysthyroid optic neuropathy. Comprehensive MAP‐MRI parameters analysis of the entire visual pathway enables a deeper understanding of disease involvement, provides novel insights into the early accurate diagnosis and ...
Mengsha Zou +7 more
wiley +1 more source
Clinical Ophthalmology, 2015 Thayalini Shanmuganathan,1 Christian Girgis,2 Hooshang Lahooti,1 Bernard Champion,1 Jack R Wall1 1Department of Medicine, Nepean Clinical School, Nepean Hospital, The University of Sydney, Sydney, 2Department of Medicine, Westmead Millennium Institute ...
Shanmuganathan T +4 more
doaj
Teprotumumab for Thyroid Eye Disease: Efficacy and Impact on Orbital Decompression Utilization
Laryngoscope Investigative Otolaryngology, Volume 11, Issue 1, February 2026.Teprotumumab has been proven effective in thyroid eye disease and associated exophthalmos management. Since its FDA approval in 2020, teprotumumab therapy has been a popular choice for managing exophthalmos which has resulted in decreased utilization of orbital decompression surgery, from 36.8% between 2015 and 2020 to 11.1% TED patients between 2020 ...
Nitish Kumar +5 more
wiley +1 more source
Thyroid ophthalmopathy in hashimotos thyroiditis with hypothyroidism- an unusual presentation [PDF]
, 2015 Thyroid associated ophthalmopathy is an autoimmune disorder, most frequently encountered in hyperthyroid state, especially seen in Graves’ disease and is rarely associated with hypothyroidism.
Karnalli Jagannatha +3 more
core +1 more source
Therapeutic Targeting of the IGF Axis
Cells, 2019 The insulin like growth factor (IGF) axis plays a fundamental role in normal growth and development, and when deregulated makes an important contribution to disease.
Eliot Osher, Valentine M. Macaulay
doaj +1 more source
Exploring tear fluid biomarkers and the ocular surface in thyroid eye disease
Acta Ophthalmologica, Volume 104, Issue 1, Page e28-e38, February 2026.Abstract Purpose To examine ocular surface changes and inflammatory tear fluid biomarkers in patients with thyroid eye disease (TED). Methods We included 106 Graves' disease (GD) patients (36 without TED, 32 with active and 38 with inactive TED) and 106 age‐ and sex‐matched healthy subjects for ophthalmological evaluation, including ocular surface ...
Mikael Thomassen Neset +13 more
wiley +1 more source
Cross-sectional study of thyroid associated orbitopathy in a South African thyroid clinic
Journal of the Colleges of Medicine of South AfricaBackground: Thyroid-associated ophthalmopathy (TAO) is a common and debilitating manifestation of Graves’ disease (GD) associated with poor clinical outcomes including impaired quality-of-life (QoL) and socio-economic status.
Sandra De Vasconcelos +3 more
doaj +1 more source
TSHR‐Targeting Nucleic Acid Aptamer Treats Graves' Ophthalmopathy via Novel Allosteric Inhibition
Advanced Science, Volume 13, Issue 4, 19 January 2026.This study presents YC3, a novel inhibitory TSHR‐targeting aptamer, as a promising therapeutic for Graves' ophthalmopathy (GO). YC3 suppresses pathological phenotypes in human orbital fibroblasts and improves outcomes in GO mice by binding to a previously unidentified allosteric site on TSHR, demonstrating the potential of aptamers in advancing ...
Yanchen Zhang +16 more
wiley +1 more source